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Rheumatoid arthritis (RA) is the most common inflammatory form of arthritis. It is characterized by inflammation of the synovial (joint) lining of multiple joints, usually presenting in a symmetric manner (meaning one side is like the other).

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Early on, small joints such as the hands, wrists, ankles, and feet are involved. As the disease progresses, larger joints also are affected. Virtually, any joint can be involved. (less info)