The Cincinnati USA Regional Chamber is the nation's fifth largest chamber, representing the interests of nearly 6,000 member businesses. Our mission is to capture Cincinnati USA as one of the world's favorite American business centers. The Chamber serves its membership and the Cincinnati USA community through economic development, government advocacy, festivals and events, regional vision and collaboration, money-saving benefit programs, leadership and networking opportunities and educational programs. Twice in the last decade, the Cincinnati USA Regional Chamber has been recognized as the national chamber of the year.