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The insulin receptor tyrosine kinase in action
antonscottgoustin
555 views
Imagine you are inside the cell, looking at the enzymatic machinery of the insulin receptor (tyrosine kinase) in its activated form. The magenta molecule in the middle is ...
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A 3-D model of the insulin signaling scaffold IRS-1
antonscottgoustin
91 views
A 3-D model of the insulin receptor-associated signaling scaffold called IRS-1 discovered by Morris White at the Joslin Diabetes Center at Harvard Medical School. The prot...
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Model of alpha2-HS-glycoprotein (Ahsg)
antonscottgoustin
87 views
Three-dimensional folding model of rat Ahsg showing at lower left in marine blue, the putative epitope HRTHHDLRHAFS that mediates interaction with the beta-subunit ectodoma...
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Human insulin receptor tyrosine kinase in active conformation with IRS1 pYMXM site in its mouth
antonscottgoustin
1,724 views
Stevan Hubbard's Xray crystallographic data (pdb 1IR3) were taken to generate a ribbon diagram using PyMol. The N-lobe of the protein is colored in aqua and pastel blue, a...
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pymol INSRNPXY IRSPTB
antonscottgoustin
3 views
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Nitrotyrosine site in ERK1 not in the substrate cleft
antonscottgoustin
30 views
The upper lobe of the ERK1 kinase is the beta rich structure in dark blue. The lower lobe is pastel aqua. Between these lobes is the ATP and protein substrate binding cle...
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pymolBimMcl1 2NL9
antonscottgoustin
6 views
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Human prion protein in 3-D showing high degree of alpha-helical structure
antonscottgoustin
4,508 views
Made using PyMol based on PDB file 2KUN.
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Vote for Congressman Carolyn Kilpatrick in Tuesday's Primary Election
antonscottgoustin
163 views
A personal endorsement for Congresswoman Carolyn Kilpatrick of Michigan's 13th Congressional District
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A 3-D model of human Ahsg, a natural inhibitor of the insulin receptor tyrosine kinase
antonscottgoustin
699 views
he polypeptide chain is colored from N-terminus (blue) to C-terminus (red) in rainbow. The white residues are thought to be the amino acid side chains which engage the ext...
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