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WatersCorporation

Introducing the Waters ionKey/MS System

1,306 views 4 months ago
With an ionKey/MS System, Waters transforms what your analytical laboratory can accomplish. The ionKey/MS System offers a new approach for getting exceptional sensitivity, robustness and ease-of-use out of mass spectrometry. It physically integrates a UPLC separation into the MS using a novel plug-and-play iKey Microfluidic Separation Device. The ion/Key MS System combines the ACQUITY UPLC M-Class and Xevo TQ-S systems. At this scale of chromatography, the savings in solvent use approaches 90%.

Learn more: http://www.waters.com/ionkey Show less
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ionKey/MS System for microfluidic chromatography Play

ionKey/MS integrates the ACQUITY UPLC M-Class System with the industry-leading Xevo TQ-S mass spectrometer, which enables the lowest detection limits to be achieved for the most challenging analyses.

Designed for the most demanding quantitative applications, Waters mass spectrometers provide unprecedented levels of sensitivity and the ultimate in quantitative performance.

ionKey/MS provides the same 2.1-mm I.D. UPLC chromatographic performance you know in a 150-µm I.D. channel packed with 1.7-µm particles, providing tremendous improvements in sensitivity.

Learn more at www.waters.com/ionkey

ACQUITY QDa Detector Play

Separating beyond question: Bring the power of mass detection to your chromatography laboratory. With the ACQUITY QDa Detector, minimize the risk of unexpected peak coelutions or components by using UV and mass data together, and confirm trace components with the analytical confidence of mass detection. Whether you use UPLC, HPLC, or purification (preparative chromatography), enhance the analytical value and productivity of each analysis.

Convergence Chromatography and the ACQUITY UPC2 System Play

UltraPerformance Convergence Chromatography (UPC2) is a broad-based, complementary analytical platform that is taking its place alongside LC and GC as one of the three essential separation technologies for modern laboratory analysis.

There are three main forms of chromatography: gas chromatography (GC), liquid chromatography (LC), and now convergence chromatography (CC). While all three use a stationary phase to interact with compounds of interest and a mobile phase to move compounds through the stationary phase and achieve separation, the techniques differ mainly by the mobile phases used.

GC is defined by using a gas as its mobile phase, LC is defined by using liquids as its mobile phase, and CC is defined by using both gas and liquids. It is this convergence of mobile phases in combination with a far greater choice of stationary phases that makes CC a powerful additional choice for laboratory scientists.

www.waters.com/upc2

All about NuGenesis 8 Play

Waters NuGenesis Lab Management System uniquely combines synergistic data, workflow, and sample management capabilities to support the entire product lifecycle from discovery through manufacturing.

The user-centric platform encompasses NuGenesis SDMS, a compliant-ready data repository, NuGenesis ELN, a flexible analytical electronic laboratory notebook, and NuGenesis Sample Management. NuGenesis seamlessly links data from the lab to the business operations of the enterprise with functionality such as sample submission and results review, stability testing, scientific search, multi-vendor software connection, laboratory inventories, data retention and legal hold, and laboratory execution methods.

Learn more: http://www.waters.com/nugenesis

Hydrogen Deuterium Exchange with Mass Spectrometry (HDX MS) Play

For higher order structure studies, hydrogen deuterium exchange with mass spectrometry -- alternatively referred to as H/D exchange, HDX, or HXMS -- has become indispensable for biotech companies.

Waters has turned what was a highly manual analytical process, where success was dependent on technical skill, into an integrated and automated system solution. This system leverages high-pressure nano- to microscale UPLC separations and high-resolution MS^E mass spectrometry to answer important questions about biotherapeutic protein dynamics, conformation, and interactions.

HDX MS studies include epitope mapping, protein-drug binding, protein-protein and protein-ligand interactions, aggregation, effects of mutation on protein conformation and dynamics, localization of conformational changes as a result of formulations and stability testing, and structural comparabilities studies between an innovator biotherapeutic and a biosimilar.

See more at www.waters.com/hdx

Video posters Play

See how our UPLC and MS technologies are used in a variety of applications.
Case studies and interviews with leading laboratories, why they choose to partner with Waters, and how our solutions are improving their laboratory operations.
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