Congresswoman Mary Bono Mack represents California's 45th District, located in Southeastern California's Coachella Valley region and Inland Empire, which encompasses a diverse geography including deserts, mountains and agricultural regions, as well as the Colorado River and the Salton Sea.

Bono Mack serves on the U.S. Energy and Commerce Committee, which has broad jurisdiction over issues such as energy, telecommunications, health care and the environment.