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Raised in Dallas, Texas, deeply immersed in the arts, Loeb studied piano and music theory and wrote her first original songs with lyrics while still in her early teens. She earned her degree in comparative literature from Brown University, where she experienced her first taste of musical success with the duo, Liz and Lisa. In the early '90s, Loeb moved to New York where she became a favorite on the Manhattan club circuit and surrounded herself with like-minded young musicians, actors and writers.

In 1993, Loeb's New York neighbor and pal Ethan Hawke recommended her to Reality Bites director Ben Stiller, who in turn included "Stay" on the hit film's soundtrack. Confirming Loeb's prodigious talents, the Platinum-selling "Stay" earned both a Grammy nomination and a "Best New Artist" Brit Award and resulted in a record deal with Geffen Records.

Making good on her successful debut single, Loeb followed with acclaimed CDs, including her Gold-certified debut Tails (1995) and its follow-up, the Grammy-nominated, Gold-certified Firecracker (1997). In 2002, Loeb ushered in the new millennium with a pair of CDs, Cake And Pie and Hello Lisa. Reuniting with her college music partner, Elizabeth Mitchell, she created the children's CD and companion board book Catch The Moon, released in 2004. Most recently, Lisa crafted a recording sculpted from recent events and her own experiences. The Way It Really Is (2004) that offered listeners a deeply personal musical journey.

Coinciding with her new television show, Universal Music Enterprises is releasing The Very Best Of Lisa Loeb (2006). Featuring 18 selections, the record includes a selection of songs off five albums from 1995 to 2004, from the orchestral "Furious Rose" to the rocking "Fools Like Me" to the stripped-down acoustic "Sandalwood," as well as the most memorable tracks from her career to date. A special addition to the collection is "Single Me Out," the theme song to the TV series. The literary Loeb also penned the album's liner notes.