MHC Class 1

[ThePesma]

They forgot to mention that the alfa3 domen is a constant part of this molecule and is responsible for recognition by cd8+ T.

[spontaneousbaba]

hey thankyou for the upload

[vanapril428]

This person's voice is distracting, she sounds so pretentious

[jorisvdv1989]

yeah MHC class 1 is recognized by CD8+, and the APC needs to be a virus, that's why all cells have a MHC class 1 because they can all be infected by a virus..

[hasabunso]

The APC could also be from an obligate intracellular bacterial infection, as both types are processed intracellularly.

[Ripside2]

@jorisvdv1989 all NUCLEATED cells...

[Celltypewhatkind]

hi

does antigen present has to be virus

[MAlam21689]

@Celltypewhatkind APC = b cell , macrophage, dendritic cell... now all of these distribute to exogenous which means it can not bind to virus... viruses are all endogenous therefore mhc class 1 represented on all nucleated cells except for rbcs because rbcs are not nucleated only in one conditions rbc get nucleated and thats postsplenoectomy .... are the ones that mostly fight off the virus via CTL if u have a MHC class 1 deficiency ur NKCs take over [natural killer cells] goodluck!!!

[leaffan27]

Actually, it's from an interactive CD I purchased along with one of my biochemistry textbooks

[c4gray]

It's probably from the same company. I recognize the woman's voice, and the video/cartoon's layout.

[c4gray]

You took this from "The Cell". Nice.

[strek0655]

Not from coopers "The cell" but rather from essential cell biology from garland sciences. I have both.