Oxygen Dissociation/Bohr Effect/Chloride Shift Revision Video

[SingerBelfast]

that music is very distracting, but good wee video.

[dakingisgman]

@SingerBelfast Is your volume control knob broken?

[evilelton]

Great music + concise, thanks!

[viapin]

Techno and medicine - a way to my heart

[viapin]

Techno and medicine - is a way to my heart

[VashDW]

-__- Spelled Hemoglobin wrong..

[AliceRolley]

@VashDW It's not wrong - it's the british spelling. :)

[VashDW]

@AliceRolley o0o0o0o0o0o fo real? didnt kno that, thnx

[AliceRolley]

@VashDW No problem :)

[fordy93]

@VashDW dick :)

[mattmatt6906]

At pH 7.2 (versus 7.4 in the lungs) and pCO2 of 40 Torr, the combined effects of these phenomena result in hemoglobin-oxygen dissociation close to 90% (compared to 77% under normal conditions). These conditions are consistent with blood conditions under physical exertion, where lactic acid increases blood acidity, and combustion increased CO2 concentration. The body is truly an amazing thing.

[mattmatt6906]

If a cell needs energy, it likely needs Oxygen, to act as the final electron acceptor in the electron transport chain. Hydronium also plays a role in the Bohr effect. Increased H+ in the hemoglobin environment leads to the formation of a salt bride between particular residues in the protein structure. This, too, leads to increased stability of the T form, which has a lower affinity for oxygen.

[mattmatt6906]

You do not explain why the Bohr phenomena occurs, you offer an equilibrium mechanism. The Bohr shift occurs because CO2 associates with the nitrogenous ends of amino acids present in the hemoglobin structure. These interactions form ionic carbamases, which enhance stability of the deoxymyoglobin structure (T-state of this allosteric protein). This results in decreased oxygen affinity in the tissues. This is helpful when cells are undergoing combustion processes such as when they need energy.

[AliceRolley]

@mattmatt6906 This video is for the WJEC A level specification, as mentioned in the description. It might not explain everything to a full extent, but it says the basic information and matches the WJEC specification.

[banjjakbanjjak]

what font are you using?

thankQ for the upload!!

[NorwegianBastard]

I found this video useful, especially the part regarding the Bohr Effect/Bohr Shift. I attend at the Anglo-European College of Chiropractic in Bournemouth and my Molecular Physiology assessment is in 5 days, so I am trying to use as many channels possible for the input of knowledge before the axe drops! xD

Cheers! *thumbs up*

[AliceRolley]

@NorwegianBastard Thanks for the comment, glad you found my video useful! :) Good luck in your assessment! :)

[lainemichelleallen]

won't know for a couple of days but I am borderline failing the subject so I have to do well in it... but I was thinking of this during my exam haha....

[lainemichelleallen]

yes.... had my exam this morning and was thinking about this lol :)

[AliceRolley]

@lainemichelleallen Cool! :) How did it go?

[pauline2703]

Its quite well explained, but the music is dreadfull... sorry! had to be said :P

[AliceRolley]

@pauline2703 Lol I can understand, dance music isn't everyone's cup of tea :) Glad you liked it (bar the music) :P

[rexexdesign]

@AliceRolley I loved the music :)

[AliceRolley]

@rexexdesign Thanks :) lol

[lainemichelleallen]

that was a really good summary thanks alice :)

[AliceRolley]

@lainemichelleallen No worries! Hope it helps :)

[missrene1]

Hey thanks for the video (- the music), it totally helped break down chloride shift, but you spelled hemoglobin wrong. But thanks anyways :C)

[AliceRolley]

@missrene1 No worries glad it helped! :) It's spelt that way in Britain :P Thanks for the comment! :)

[theartofbone]

At first I thought, wow, that music sucks, we can do without it. But then 2 minutes into it I was like, hmmm, not bad, and decided to pay/dl it. :)

-Non Tehcno/Trance/House listener/IMG bout to take Step 1

[AliceRolley]

Everyone has different tastes :P Glad you liked it in the end :)

[dyl650]

i'm resitting HB2  tomorrow, this video really helped

[AliceRolley]

thanks, im resitting BY2 tomorrow as well :( not looking forward to it. good luck in your exam :)

[dyl650]

neither am i, good luck to you too

[dyl650]

how did it go?

[AliceRolley]

hey, it went ok thanks, better than expected. and yourself?

[dyl650]

i think it went well, better than last time, not looking forward to BY4 on monday though

[c4gray]

FETAL! Not FOETAL! lol British English ;)

[TypicalVideo]

Can be spelt both ways. Doesn't matter.

[AliceRolley]

@c4gray I'm from Britain, so I use that spelling :P It doesn't matter anyway, you can use whichever spelling and still understand the video :)

[hawkssens]

THANK YOU!!!

I finally understand.

[Chocolado1]

Dude this kicked arse ty soo much : ) Genius... Will help soo much with my AnP 1 +2 exams

[maplemusketeer]

haha thanks for putting this together. I was wrestling with Bohr Effect etc in the damn textbook... this helped me before I once more go into the breach ;)

[galantoslav]

this is hilarious, great vid

[Porganised]

great pic at 2:10. thankyou. god post too. science and personality. who'da thought?

[chadprink18]

love the song! what's the tittle? or album?

[AliceRolley]

The title is Silence (DJ Tiesto Remix) and the artist is Delirium. It's from the Dave Pearce Trance Anthems 2008 album :)

[BonjellaJunkie]

Fair do's.

Exam tomorrow,

This is pretty epic.

(Y)

[oxoMaruoxo]

Thank You! :D And I love this song