When people say reverse ageing does that actually mean you can take an old person and via processes they become young again? or is that not possible? I'm talking about genetic engineering, how could that work if possible?
@deanmullen10 Reverse ageing? Already happening in mice and rats - lower blood pressure and increased skin elasticity on long term basis after 1 month treatment. See Alteon research.
REAL I DISCOVERED THE SECRETS OF IMORTALITY THE RELEVALION IN TIME IS TO BE FOR EVER IN THE SAME SHAPE EMOTIONAL MENTAL PHISICAL LIKE ONE TEENAGER..WHO WANT TO REALIZE THIS MAN OR WOMAN COMPATIBLE CAN CONTACT ME.THE FIRST OF ALL LIKE IMPORTANCE IS TO ATTRACT MUCH MORE YNN AND YANG ENERGY AND TO BLEND THIS IN YOUR BODY WITH HEALTY FOOD.THEN YOU MUST TO KNOW TO THING AND DO NOT CREATE BLOCKAGES IN YOUR BODY.YOU CAN LIVE TILL THE ACCIDENTAL DEATH.MY ID MERKHURY@YAHOO.COM.
Stem Cells & Genetic Programming. That's where it's at. I wan't to be 20 again because my first try was a falure,I want a redo depriving a new life into this world See the problem? The stem cell discovery can & will keep people alive forever. There will have to be laws to stop births. This is an interesting dilemma in this future world. As is Paramedics bring the dead back to life.
Ageless individuals would not have to constrain themselves to tasks that take only decades or years, but expand their minds to activities requiring centuries if not millenia of research to complete. Once immortal, it wouldnt matter about the time scale. If you choose to become ageless, you could wait a couple hundred years to have children in order to solve over population issues. We could also expand into the ocean, it does cover seventy five percent of the earth... or even space, open minds
I just orderd stem cell pills will this build muscle like i was a teenager? and also will this be the new breakthru of sickness and rebuilding our hair like we were kids?
If somone can get progeria = rapid aging disease, then there must be a counterpart of this disease, but the thing is that it has never occured before, so we never know
pjdixon hope you'll take a look at our website and review our resveratrol product. It is made from the highest quality grapes from the French Wine Country and we have tested it and it does turn on the longevity gene. Hope you'll check it out!
I've seen your videos all around the internet, and I feel inspired, I LOVE futursists! I, myself, would like to be one, when I grow old(er).
I was just wondering though, when can we expect to see this 'cure for aging', and when will it be available for people with a monthly income of, say, $3300?
Also, what are your points of view in Aubrey de Grey's work in SENS?
Although by the time we find a cure to aging will be a while away, I am still very excited about it. I dont hear many people talking about ending it, people discuss about it every now and then on science shows, but my excitement makes it seem as its going to be cured soon.
Pjvdixon thats true. So would mean that tackling issues head on before any problems arise would improve the chances of positively affecting the system as a whole? As in taking aging precautions at a young age. Perhaps some vast good can come from studying corrective applications to degrading tissues in younger bodies.
When you look into IC (irreducible complexity) systems and Medical science, and begin to understand how the systems of the body depend on on another, that the correct IC concept to keep in mind is that such systems depend on every internal component for continued function. As we get older, our subsystems (eg. organs) begin to fail, which affect other systems which may depend on the failing system - affecting the rest of our bodies.
If there were a way to correct this...we could live forever...!
im 18 years old...19 this year and people say i look 15 or 16:) haha well i might be abit young yet to say i age slow but its the same with my older brother and sisters and mum
well im 55 years old, but i look like im 30 years old, and how? well I entombed my home with tinfoil, and my garden is also entombed, and for lightning i use solar energy for lightning. with the Microwave i discovered our sun kills our cells in a similiar way, my curtains are also layered in tinfoil. I'm very excited to say I've aged 2 years in 25 years. My doctor said beware, prophetically, the price of tin is about to Increase in price!
Ok now i see where your comming from but I have an invention though not realized, but is compleatly and utterly possible to be made that abides by all laws and rules of science and reality. It can make a person immortal from an atomic level. constently replacing bad or aged cells or even your entire structure with newer versions. Also it sorce of energy for those who want to be technical about it is from protons thus making perpetual energy. protons dont run out of energy.
Does your brain chip work with government sponsored mercury poisoning? After all you're behind population control, so don't give us that shit about reverse aging as you peddle your 666 implants.
WE NEEd aging so that the old can die off to leave room for the young. Otherwise the world will get VERY overcrowded. The only exception is if we all stop having children so its she same few billion immortal people (all adults) but people like to have babies.
1st: we have plenty of room in our world, since we have like what, 6 billion people?
2nd:with aging cured, people wouldn't have the need to 'replace' them by having kids.. so they wouldn't reproduce as much
3rd:real estate is already being sold on the moon and in mars (not sure about the moon, though) to build houses or something close to houses, in a future near us, so we will populate another planets/satelites
4th:we DO NOT need aging..look it up and you'll see
@Zurround100 if that were to happen then they would prob just kill most of the people in prisons lol, like murderers and rapists to leave more room xD or they might have to start exploring space properly and find other Worlds like ours to live on...tryn to not sound silly but it could be possible
we have telomeres which even with stem cells are structurely necessary. we all gotta punch the ticket. besides going up into space traveling close to the speed of light and making a big semi circle for a few million years back on earth, you gotta go sometime. even stable matter will eventually decay
theres no way to stop aging. superficial features will never stop all thats in you. we genuinely die of old age from gradual misfolding of proteins which makes cells predictably more damaged but down throttling in potential. and certain key endomembrane produced antioxidants so oxidative stress builds up. stem cells would be great but it isnt the fountain of youth, it can allow you to live a few hundred years with a bit of skin firmness, color and not going senile or bald, and not emaciated.
rockfish do not show signs of aging, go look it up.. It is possible, many SCIENTISTS say, you might just be saying that because it looks too much for our technology right now, but who knows in 20, 30 years from now?
i have looked it up, rockfish age and die, they get alot of slim coat issues when they get older and more susceptible to fin rot. the only animal that doesnt age after maturity is the hydra and can even revert to its larval stage
@Pimpmastahanhduece like evgeniy13 said, 'What is we could tweak those DNA ends or rather telomerase activity? It's not like building anentirely new body.'..
if we tweaked telomeres, we would deteriate terribly over that longer life. telomeres are adjusted correctly for DNA degradation which is unavoidable with constant mitosis and RNA sequencing. what we can do is perfect the epigenome so we produce better proteins which counteract the main cause of aging, oxidative stress, mainly intracellular antioxidants which our cells produce and cant just be consumed as is.
And by the way, even if tweaking telomeres doesn't work (which I don't think is still proven to be a failed theory..) we can always try to reapair the damage of ageing in our bodies, which means that even though we age, we can recover from it, like, muscle deterioration, brain damage and any type of physical damage. That at least, you might admit, is a more possible reality for a 'closer' future (closer because 20/30 years in science isn't that much, altough we are evolving at a high rate today)
by the way, telomeres' conversation apart, you seem like a reasonably smart man...What about this nanotechnology thing? I mean, I'm sooo excited with all these new developments in this area.. it is just astonishing..we are evolving more in 2010 than in the past 20 years or whatever, its incredible... and also, you must agree with me, nanotechnology, when it reaches its peak, will ultimately let us live much MUCH longer, because it will be able to do reparations at cell-level, or atom-level!
@Sevilfate yeah but you have to starve and not move a lot .... watch some documentaries from Michio kaku .. you can find the "time" series and one of them is on life time..... actually I think the documentary is called "life time" :)
That's not really what it means. If biological immortality occurs in us then our bodies will be very different, even on a visible level. The promise of ending aging brings with it the promise that all disease will be abolished. So basically we're all going to become jellyfish (not literally, just figuratively).
Chance of dying depends on frailty. Normally the older the body the frailer it is. So there is less place for body systems to outmaneuver the disease. So the chance of dying grows with aging. It's 99,8% chance to die at age 90something
We know telomere shortening is causing aging, and superscentenarian offsprings have longer telomeres. What is we could tweak those DNA ends or rather telomerase activity? It's not like building anentirely new body.
Not necessarily. The main reason humans reproduce is to fulfill a biological imperative they have that says "we're not going to be around forever so we need to propagate our DNA further". Biological immortality would probably erase that imperative from us after a certain amount of time, when we show that we no longer need it.
Everyone needs to stop worrying about overpopulation.
When the need arises, we will allow for laws that regulate reproduction, have new technologies to increase production for all of our needs, and/ or colonize in new places, not necessarily on other planets.
@curingaging00 orly? if we cure aging the world will self destruct... no jobs, no access to public services because they are too strained, and will cost billions to expand, pollution, extinction of natural resources in triple the time... etc etc..
over the years as the population gets bigger anf bigger, there will be no food, no power, and depression!
@MrJasonSmarts well, there are alternatives then simply letting people just die off in the masses.
Instead of just thinking an end to aging as a technology by itself, think of what other technology would be like by the time we cure aging...
by the time life extensions are very advanced, so would other technical advances such as agriculture, etc, etc. Birth rates have been declining and are likely to decline even more.
letting people suffer and die off in the masses is not the solution.
@MrJasonSmarts we have to think outside besides just letting people die.
If overpopulation was such a big problem, then why do we still continue to save lives? why do we still try to find cures to cancers and other diseases even though some consider us currently overpopulated?
it is our moral obligation. aging shares a similar characteristic with other causes of death
they are: suffering, and death. only different is aging kills 100,000 a day 2/3DS OF ALL DEATHS!
thats why we are investing heavily on renewable energy, and will eventually on vertical farms. renewable energy will open the windows to a much higher carrying capacity and a lessened human foot print.
It will cost billions to expand, aging is already costing our healthcare trillions. we spend 2 trillion+ usd a year on healthcare and over 2 trillion of that is on elderly.
actrually even if u stop aging people will still be dieing, just at a much much slower rate. yes there will still be children, just not nearly as much as now.
i dont agree the birth rates will continue like this...
the globle pop rises 211k a day 100k ppl die from aging per day. if we cure aging that doesn't mean pop will increase 311k. because, immagine if you can choose when to have kids no mater what age. 50,80,140,200,10000. alot of people such as myself would decide to have kids much later in life.
the birth rate are expected to level at 2-3 per family by 2050. by 2100 they predict birth rates will be around ~1.5 per family.
I am not so sure. I have seen a midshift with Arabs where 10+ children to one wife is normal was considered normal but their children only want 1 or 2 children. I mean in the west we are not increasing our population too much. I have 2 children and love them dearly but if I were to live indefinetely I doubt I'd have more.
Death is a biological hindrance that we have programmed ourselves to accept, in order to function on a day-to-day basis. It's a biological problem we will soon solve.
Yes, and I when possible I would myself like to be a product of this solution, some may not agree.
Curing aging would be saving lives on a monumental scale. It would be like curing any disease.
What I'm wondering is... because we could save such a tremendous amount of lives, that could potentially live very long lives, how will this conflict with the problem of overpopulation that we see even without this cure.
I wonder what will all those people who have devoted their entire lives to their religion will think 300 years from now when we are all living healthy, wealthy, wise, and without violence?
I cant wait for humanity to do away with the primitive parts of our brains that cause us to become angry and hostile.
Want longer life? Just use Alex Chiu's Immortality Rings. This guy already figured out a way to stop humans from aging and become physically immortal. These guys are still in dark ages searching for immortality? Alex Chiu already got the technology.
Anyone who is interested in this, look up the work of Aubrey de Gray. He is a British researcher into this field, that claims the first generation to live to 1000 years old or older has already been born; and that the technology capable of reversing aging either already exists, or is on the verge of being developed in our lifetimes.
the future is coming faster and faster. everyday things like these new iphones...people don't even think about it, it's already common place. just 20 years ago it was science fiction. the world is changing at an accelerating pace, and medicine is part of that. the deeper questions are, of course, how we as a society can deal with this technology and it's social implications. can we sustain a planet where people just don't 'age' in the natural sense?
I see a lot of people calling for "population control", that we are running out of resources and space on this planet...which is utter RUBBISH. We need to adjust how we live, and use our resources more efficiently. We can fit 20 BILLION people on this planet - do your research. A long lived population will alter our perspectives on the environment and what we want for our children and grandchildren since we will be living it. This would be the greatest thing for humanity since discovering fire.
There is so much that we just don't know. My grandparents lived into their 90's in a rural part of Lanarkshire, yet just 10 miles away you will find the average life expectancy in a city like Glasgow to be as low as 59 in some places. My grandfather liked a whisky and he smoked, it made little difference to his health. I think it is almost completely genetic. As a non-smoking ex-athlete I am 43 but I believe I will easily see the other side of 100. I've been with vitamins and DHEA.
Cont'd. My father and mother are 79 and 77respectively, and both very healthy. They both worked until retirement age but I believe their lower-middle status has a direct influence on their longevity. My parents both take vitamins and daily aspirin. As a science writer my life is much less stressful still. I believe my experiments with hormones and vitamins, and regular workouts at the gym, will directly extend my life, and quality of life. It is bith a state of mind and our whole approach.
Cont'd. In the past 2 years, I have lowered my blood pressure from a diastolic in the mid 80's to avg. 72. Simply by changing how I prepare my food. I strongly believe that the answer to a long-life with a good quality of life, is a lot simpler than most people realise. As a Scot living in Texas, I have adopted some of the better parts of that culture and rejected the less healthy ones, this seems to work well with my overall plan. I'm doing it with readily available products. Regards, David.
Hello Dr. I am very interesting about the human aging now. In my opion it is very complicated area, because human body is a very complicated thing, especially, when you want to slowdown, or even to stop human's body aging. How do you think, wich will make most infuential work in stoping aging in the future (if it is possible, of course): biochemists, molecular biologists, geneticists or bioinformaticists? I'll be very thankful for the answer.
Hello dear Dr. I am very intersting about the human aging. In my opinion This must to be a very complicated area, If you want to expand human life radicaly, yes? How do you think, wich people will made most influential work in the future: biochemists, molecular biologists, geneticists or scientists from bioinformatics?
reduce SIR2, SCH9, & RAS2 genes in yeast, life = 6x longer. Mammal counterpart is SIRT1 to resist oxidants, store nutrients. It regulates P-genes to make less cells to fight infections. Much like HST1, no good.
uh....the part about 160 year life span.....its 160 MOUSE years, not human years, a mouse life is much shorter than a human but when they say 160 years of life that if they did the same thing to a human what they did to the mouse: the human would live 160 years
Dr.,How do you know, that we understand about human body ENOUGH to stop aging? Maybe our molecular systems, from wich is made our bodies, can't to be trasformed in that systems, wich can to function forverer? And whay do you think so? And I know that gerontoligists, wich is working all the time in aging, is very critical about that...?
hello, just came across your show, I thought it was amazing! I am interested in nutrition and exercise for hoping for a slower aging process, what else can I do? All I know is to say alive until someone finds the holy grail.
uh Mr. Dixon, i was just wondering but would it be too absurd of an idea that maybe "aging" is simply a genetic disease.....a flaw in the genetic code? maybe?
Thanks, Virgin G are doing amazing things. For more of my videos on this issue SUBSCRIBE to my next videos - press ORANGE BUTTON top RIGHT. Patrick Dixon
also i am a subscriber of urs, i observed the video with virgin galactic...indeed a fantastic job those guys are doing and congratulations to the whole engineering team behind this project. Literally stunning
and how do u suggest this is accomplished? telomerase? immortalised cell lines and cancer exhibit this phenotype...what is ur scientific hypothesis? how do u think this can be accomplished? could u pls indicate me the biological toold u would operate with?
Thanks. Yes turning on telomerase for short time (too long risks cancers), and other targetted approaches. For more of my videos on this issue SUBSCRIBE to my next videos - press ORANGE BUTTON top left. Patrick Dixon
I am at Imperial college if u know it in london. u suggest experiments on mice but u have to understand that although the genome is 99% similar there is a huge degree of altered difference between biochemical pathways in mice and humans. Take for example Th-IL-17 cells. Originally it was thought they did the same thing exactly. The transfer from mice to humans is a very long process. As a physician u should at least indicate that and not give ppl hope like this concrning immortality
Thanks - yes that is true. The jump from discoveries in mice to humans is always complex and tenuous. But nevertheless the fundamental cellular mechanisms of ageing seem to be relatively few in mammals. Patrick
what? aging.....is a disease.....and we will find the cure to it just as every other disease on this pathetic mudball of a planet as well as any other planet we find and colonize
Alteon did some interesting work in mice and rats on blood pressure. The drug permanently lowered BP and at the same time improved elasticity of the skin.
calorie intake only works for rats. There is no scientific proof the same is true with humans.
I don't know much about the process, but telomerase is the key. Find a way to activate telomerase without increasing cancer risks and without stem cells.
there isn't any evidence for humans - yet but many that practice this are certainly receiving some health benefits. We will have to wait many many years to verify if it works or not; I will bet that it does to a certain extent.
Add to this proper diet, exercise, aggressive supplementation add in a pinch of hope and we may live long enough to see further breakthroughs.
Life is too short to think how can we live longer.. Let's think of how can we live a life that's full and the rest will follow..
happinesson 2 months ago
@happinesson
For you it is.
For others thinking how to live long is a worthy pursuit.
1NX9 1 month ago
When people say reverse ageing does that actually mean you can take an old person and via processes they become young again? or is that not possible? I'm talking about genetic engineering, how could that work if possible?
deanmullen10 3 months ago
@deanmullen10 Reverse ageing? Already happening in mice and rats - lower blood pressure and increased skin elasticity on long term basis after 1 month treatment. See Alteon research.
pjvdixon 2 months ago
@deanmullen10
I would also look in "gene therapy".
Scientist may be able to reverse aging by altering your DNA structure.
1NX9 1 month ago
Pharmanex .
wecu4dk 5 months ago
@zephranna01 A good question. It doesnt. Natural environmental instances such as disasters or even murder would still llimit the population.
DreamersOfReality 5 months ago
REAL I DISCOVERED THE SECRETS OF IMORTALITY THE RELEVALION IN TIME IS TO BE FOR EVER IN THE SAME SHAPE EMOTIONAL MENTAL PHISICAL LIKE ONE TEENAGER..WHO WANT TO REALIZE THIS MAN OR WOMAN COMPATIBLE CAN CONTACT ME.THE FIRST OF ALL LIKE IMPORTANCE IS TO ATTRACT MUCH MORE YNN AND YANG ENERGY AND TO BLEND THIS IN YOUR BODY WITH HEALTY FOOD.THEN YOU MUST TO KNOW TO THING AND DO NOT CREATE BLOCKAGES IN YOUR BODY.YOU CAN LIVE TILL THE ACCIDENTAL DEATH.MY ID MERKHURY@YAHOO.COM.
MERKHURY 6 months ago
People need to stop trying to "live forever" and actually start LIVING!
midnull 8 months ago
Your hair does look great!
wrinklesystem 11 months ago
nice vid
FreeWebTutorialsRock 1 year ago
I define aging as the set of accumulated side effects from metabolism that eventually kills us.So it is a disease.But we will stop it!!
LightsOut4you 1 year ago
@LightsOut4you
That is one of many reasons.
You accumilate mutations via your surroundings, sun, pollution...etc.
Oh and don't forget about telomeres.
etc. etc. etc.
midnull 8 months ago
@midnull
I heard Ta-65 might infact lengthen telomeres.
1NX9 1 month ago
get crackin. Im 16, so you have lots of time if my fat arse doesnt die of diabetes (im black too, damn) or heart disease (dammit!).
Deathrune456 1 year ago
Stem Cells & Genetic Programming. That's where it's at. I wan't to be 20 again because my first try was a falure,I want a redo depriving a new life into this world See the problem? The stem cell discovery can & will keep people alive forever. There will have to be laws to stop births. This is an interesting dilemma in this future world. As is Paramedics bring the dead back to life.
FreeGlobalEnergy 1 year ago
Ageless individuals would not have to constrain themselves to tasks that take only decades or years, but expand their minds to activities requiring centuries if not millenia of research to complete. Once immortal, it wouldnt matter about the time scale. If you choose to become ageless, you could wait a couple hundred years to have children in order to solve over population issues. We could also expand into the ocean, it does cover seventy five percent of the earth... or even space, open minds
DreamersOfReality 1 year ago
Two words. Alex Chiu
covertbabo12 1 year ago
I just orderd stem cell pills will this build muscle like i was a teenager? and also will this be the new breakthru of sickness and rebuilding our hair like we were kids?
XtremeDance10 1 year ago
@XtremeDance10 ha retard stems cells cant be put into pills they are injected
pissedoffkids 1 year ago
If somone can get progeria = rapid aging disease, then there must be a counterpart of this disease, but the thing is that it has never occured before, so we never know
SteelboneNakedlunch1 1 year ago
pjdixon hope you'll take a look at our website and review our resveratrol product. It is made from the highest quality grapes from the French Wine Country and we have tested it and it does turn on the longevity gene. Hope you'll check it out!
2healthnuts 1 year ago
Obma ashould have put the trillion on life extension instead of bailouts, and we can see productivity improve a thousand fold in this century.
ASSHOLELA 1 year ago
I've seen your videos all around the internet, and I feel inspired, I LOVE futursists! I, myself, would like to be one, when I grow old(er).
I was just wondering though, when can we expect to see this 'cure for aging', and when will it be available for people with a monthly income of, say, $3300?
Also, what are your points of view in Aubrey de Grey's work in SENS?
uhuyo 1 year ago
Although by the time we find a cure to aging will be a while away, I am still very excited about it. I dont hear many people talking about ending it, people discuss about it every now and then on science shows, but my excitement makes it seem as its going to be cured soon.
curingaging00 1 year ago
Pjvdixon thats true. So would mean that tackling issues head on before any problems arise would improve the chances of positively affecting the system as a whole? As in taking aging precautions at a young age. Perhaps some vast good can come from studying corrective applications to degrading tissues in younger bodies.
executableapplet 1 year ago
When you look into IC (irreducible complexity) systems and Medical science, and begin to understand how the systems of the body depend on on another, that the correct IC concept to keep in mind is that such systems depend on every internal component for continued function. As we get older, our subsystems (eg. organs) begin to fail, which affect other systems which may depend on the failing system - affecting the rest of our bodies.
If there were a way to correct this...we could live forever...!
executableapplet 1 year ago
Yes ageing is a multi-level process. One thing affects another - but in reverse it means that tackling one issue affects many others too.
pjvdixon 1 year ago 3
im 18 years old...19 this year and people say i look 15 or 16:) haha well i might be abit young yet to say i age slow but its the same with my older brother and sisters and mum
ImSuperhuman 1 year ago
Younger people seem to be ageing more slowly - better diet etc.
pjvdixon 1 year ago
Liar! Murderer! Youtube: "Bisphenol A contaminating our food"
PhuqueU 1 year ago
This has been flagged as spam show
well im 55 years old, but i look like im 30 years old, and how? well I entombed my home with tinfoil, and my garden is also entombed, and for lightning i use solar energy for lightning. with the Microwave i discovered our sun kills our cells in a similiar way, my curtains are also layered in tinfoil. I'm very excited to say I've aged 2 years in 25 years. My doctor said beware, prophetically, the price of tin is about to Increase in price!
markfriesen1979 1 year ago
Ok now i see where your comming from but I have an invention though not realized, but is compleatly and utterly possible to be made that abides by all laws and rules of science and reality. It can make a person immortal from an atomic level. constently replacing bad or aged cells or even your entire structure with newer versions. Also it sorce of energy for those who want to be technical about it is from protons thus making perpetual energy. protons dont run out of energy.
Feel free to comment
jthunder93 2 years ago
Sounds like science fiction but possible partly in future
pjvdixon 1 year ago
Does your brain chip work with government sponsored mercury poisoning? After all you're behind population control, so don't give us that shit about reverse aging as you peddle your 666 implants.
PhuqueU 2 years ago
I am simply reporting on trends - I do not have any ties with these kinds of companies or technologies.
pjvdixon 1 year ago
WE NEEd aging so that the old can die off to leave room for the young. Otherwise the world will get VERY overcrowded. The only exception is if we all stop having children so its she same few billion immortal people (all adults) but people like to have babies.
Zurround100 2 years ago
lol read the other comments..
1st: we have plenty of room in our world, since we have like what, 6 billion people?
2nd:with aging cured, people wouldn't have the need to 'replace' them by having kids.. so they wouldn't reproduce as much
3rd:real estate is already being sold on the moon and in mars (not sure about the moon, though) to build houses or something close to houses, in a future near us, so we will populate another planets/satelites
4th:we DO NOT need aging..look it up and you'll see
uhuyo 2 years ago
@Zurround100 if that were to happen then they would prob just kill most of the people in prisons lol, like murderers and rapists to leave more room xD or they might have to start exploring space properly and find other Worlds like ours to live on...tryn to not sound silly but it could be possible
ImSuperhuman 1 year ago
we have telomeres which even with stem cells are structurely necessary. we all gotta punch the ticket. besides going up into space traveling close to the speed of light and making a big semi circle for a few million years back on earth, you gotta go sometime. even stable matter will eventually decay
Pimpmastahanhduece 2 years ago
theres no way to stop aging. superficial features will never stop all thats in you. we genuinely die of old age from gradual misfolding of proteins which makes cells predictably more damaged but down throttling in potential. and certain key endomembrane produced antioxidants so oxidative stress builds up. stem cells would be great but it isnt the fountain of youth, it can allow you to live a few hundred years with a bit of skin firmness, color and not going senile or bald, and not emaciated.
Pimpmastahanhduece 2 years ago
@Pimpmastahanhduece then why don't rockfishes and all those other animals don't get old? I think it is possible, from what he showed..
uhuyo 2 years ago
rockfishes dont get old? im pretty sure there isnt rockfish swimming around several million years old.
Pimpmastahanhduece 2 years ago
rockfish do not show signs of aging, go look it up.. It is possible, many SCIENTISTS say, you might just be saying that because it looks too much for our technology right now, but who knows in 20, 30 years from now?
uhuyo 2 years ago
i have looked it up, rockfish age and die, they get alot of slim coat issues when they get older and more susceptible to fin rot. the only animal that doesnt age after maturity is the hydra and can even revert to its larval stage
Pimpmastahanhduece 2 years ago
@Pimpmastahanhduece ah, the hydra.. maybe I was just confused, dunno.. but point proven
uhuyo 2 years ago
wikipedia()org/wiki/Hydra_%28genus%29#Senescence
Pimpmastahanhduece 2 years ago
@Pimpmastahanhduece like evgeniy13 said, 'What is we could tweak those DNA ends or rather telomerase activity? It's not like building anentirely new body.'..
uhuyo 2 years ago
if we tweaked telomeres, we would deteriate terribly over that longer life. telomeres are adjusted correctly for DNA degradation which is unavoidable with constant mitosis and RNA sequencing. what we can do is perfect the epigenome so we produce better proteins which counteract the main cause of aging, oxidative stress, mainly intracellular antioxidants which our cells produce and cant just be consumed as is.
Pimpmastahanhduece 2 years ago
And by the way, even if tweaking telomeres doesn't work (which I don't think is still proven to be a failed theory..) we can always try to reapair the damage of ageing in our bodies, which means that even though we age, we can recover from it, like, muscle deterioration, brain damage and any type of physical damage. That at least, you might admit, is a more possible reality for a 'closer' future (closer because 20/30 years in science isn't that much, altough we are evolving at a high rate today)
uhuyo 2 years ago
you agree with me, yes?
uhuyo 2 years ago
Thanks for all your interesting posts
pjvdixon 1 year ago
by the way, telomeres' conversation apart, you seem like a reasonably smart man...What about this nanotechnology thing? I mean, I'm sooo excited with all these new developments in this area.. it is just astonishing..we are evolving more in 2010 than in the past 20 years or whatever, its incredible... and also, you must agree with me, nanotechnology, when it reaches its peak, will ultimately let us live much MUCH longer, because it will be able to do reparations at cell-level, or atom-level!
uhuyo 2 years ago
Thanks for all your interesting posts
pjvdixon 1 year ago
i heard if you reduce your caloric intake it could increase you life span or reverse the affects of age.
Sevilfate 2 years ago
Possible - works in rats and monkeys
pjvdixon 1 year ago
@pjvdixon half f it is true. There is no evidence that calorie restriction ever reversed aging in any species
sondano 9 months ago
@sondano "There is no evidence that calorie restriction ever reveresed aging in any species"
Not true. Obvious you havnt read the literature. Its been well known& studied for decades.
1NX9 1 month ago
@pjvdixon
Agree.
Dont listen to the uninformed nay sayers about caloric restriction. Its been written and well known in scientific literatures for decades.
1NX9 1 month ago
@Sevilfate yeah but you have to starve and not move a lot .... watch some documentaries from Michio kaku .. you can find the "time" series and one of them is on life time..... actually I think the documentary is called "life time" :)
UroborosComplex 10 months ago
I wanna clone myself thatd be pretty cool
(^-^)
crazytuber3000 2 years ago
were you the guy on interviewed on newstalk
charlienethercoat094 2 years ago
Often in the media.
pjvdixon 1 year ago
Comment removed
cortezforever 2 years ago
If humans were made immortal we would have to completely ban all reproduction. Expect immediate castration and sterility drugs on a massive scale.
Nosighter 2 years ago
It's better to begin it now in China, India and amoung muslims.
But it better be space colonisation, not castration.
Besides biological immortality means ppl will live ony for about 300 years (due to road kill and things like that). So babies will be needed.
evgeniy13 2 years ago
That's not really what it means. If biological immortality occurs in us then our bodies will be very different, even on a visible level. The promise of ending aging brings with it the promise that all disease will be abolished. So basically we're all going to become jellyfish (not literally, just figuratively).
PsychoJosh 2 years ago
"our bodies will be different figuratively"
Chance of dying depends on frailty. Normally the older the body the frailer it is. So there is less place for body systems to outmaneuver the disease. So the chance of dying grows with aging. It's 99,8% chance to die at age 90something
We know telomere shortening is causing aging, and superscentenarian offsprings have longer telomeres. What is we could tweak those DNA ends or rather telomerase activity? It's not like building anentirely new body.
evgeniy13 2 years ago
we wouldn't even need to reproduce.
LucentTwinkle 2 years ago
To add:
Studies have shown the higher the quality of living is the less people want to have children. Which is a good thing.
Jenfucius 2 years ago
Not necessarily. The main reason humans reproduce is to fulfill a biological imperative they have that says "we're not going to be around forever so we need to propagate our DNA further". Biological immortality would probably erase that imperative from us after a certain amount of time, when we show that we no longer need it.
PsychoJosh 2 years ago
Everyone needs to stop worrying about overpopulation.
When the need arises, we will allow for laws that regulate reproduction, have new technologies to increase production for all of our needs, and/ or colonize in new places, not necessarily on other planets.
jal860 2 years ago 2
i agree.
curingaging00 2 years ago
w/ a rise in education, there's a chance for population decrease, like what's happening in the u.s. & japan
LucentTwinkle 2 years ago
Us population is increasing. Because of immigration.
TheSteffen1223 1 year ago
curing aging WILL NOT cause overpopulation.
curingaging00 2 years ago 3
@curingaging00 orly? if we cure aging the world will self destruct... no jobs, no access to public services because they are too strained, and will cost billions to expand, pollution, extinction of natural resources in triple the time... etc etc..
over the years as the population gets bigger anf bigger, there will be no food, no power, and depression!
as that what you want?
we either die, or we stop having children?
MrJasonSmarts 1 year ago
@MrJasonSmarts well, there are alternatives then simply letting people just die off in the masses.
Instead of just thinking an end to aging as a technology by itself, think of what other technology would be like by the time we cure aging...
by the time life extensions are very advanced, so would other technical advances such as agriculture, etc, etc. Birth rates have been declining and are likely to decline even more.
letting people suffer and die off in the masses is not the solution.
curingaging00 1 year ago
@MrJasonSmarts we have to think outside besides just letting people die.
If overpopulation was such a big problem, then why do we still continue to save lives? why do we still try to find cures to cancers and other diseases even though some consider us currently overpopulated?
it is our moral obligation. aging shares a similar characteristic with other causes of death
they are: suffering, and death. only different is aging kills 100,000 a day 2/3DS OF ALL DEATHS!
curingaging00 1 year ago
@MrJasonSmarts
your question about pollution and energy
thats why we are investing heavily on renewable energy, and will eventually on vertical farms. renewable energy will open the windows to a much higher carrying capacity and a lessened human foot print.
It will cost billions to expand, aging is already costing our healthcare trillions. we spend 2 trillion+ usd a year on healthcare and over 2 trillion of that is on elderly.
curingaging00 1 year ago
@MrJasonSmarts
stop having children?
actrually even if u stop aging people will still be dieing, just at a much much slower rate. yes there will still be children, just not nearly as much as now.
curingaging00 1 year ago
i dont agree the birth rates will continue like this...
the globle pop rises 211k a day 100k ppl die from aging per day. if we cure aging that doesn't mean pop will increase 311k. because, immagine if you can choose when to have kids no mater what age. 50,80,140,200,10000. alot of people such as myself would decide to have kids much later in life.
the birth rate are expected to level at 2-3 per family by 2050. by 2100 they predict birth rates will be around ~1.5 per family.
lets cure aging!!
curingaging00 2 years ago
wow really? whered u find that statistic. the globle pop rises 211k a day 100k ppl die from aging per day. THAT IS SCARY
IMakeBoringVideos 2 years ago
aubrey de grey said so and at first that sounded kinda strange... so i looked up.
it its roughly 100k actrually its like 99,392-102,291
but yea around 100k.
also read that something like 360k babies born every day 25k die from hunger 7k aids.....
curingaging00 2 years ago
wow thanks a very instersting fact. hope that more ppl start dying or this worlds gonna pop soon
IMakeBoringVideos 2 years ago
I am not so sure. I have seen a midshift with Arabs where 10+ children to one wife is normal was considered normal but their children only want 1 or 2 children. I mean in the west we are not increasing our population too much. I have 2 children and love them dearly but if I were to live indefinetely I doubt I'd have more.
SidandCoke 2 years ago
i love taking Vitager, it's really the effective for me. it made my skin smoother and younger looking.
happilylil 2 years ago
死ね!
referencesource 2 years ago
Death is a biological hindrance that we have programmed ourselves to accept, in order to function on a day-to-day basis. It's a biological problem we will soon solve.
sephg 2 years ago 3
Yes, and I when possible I would myself like to be a product of this solution, some may not agree.
Curing aging would be saving lives on a monumental scale. It would be like curing any disease.
What I'm wondering is... because we could save such a tremendous amount of lives, that could potentially live very long lives, how will this conflict with the problem of overpopulation that we see even without this cure.
P90XDoubles 2 years ago
I wonder what will all those people who have devoted their entire lives to their religion will think 300 years from now when we are all living healthy, wealthy, wise, and without violence?
I cant wait for humanity to do away with the primitive parts of our brains that cause us to become angry and hostile.
jal860 2 years ago 4
wouldn't that take away the aspect of being human? it would give way to becoming the robots we talk about today
LucentTwinkle 2 years ago
we shud cure aging.
cpisretartedmuch 2 years ago
birth and death are merely two different aspects of the same state of being.
mrsbrown333 2 years ago
Want longer life? Just use Alex Chiu's Immortality Rings. This guy already figured out a way to stop humans from aging and become physically immortal. These guys are still in dark ages searching for immortality? Alex Chiu already got the technology.
alexapollo22 2 years ago
Anyone who is interested in this, look up the work of Aubrey de Gray. He is a British researcher into this field, that claims the first generation to live to 1000 years old or older has already been born; and that the technology capable of reversing aging either already exists, or is on the verge of being developed in our lifetimes.
silverhawks 2 years ago
My wrinkles are gone bu taking Vitager, it's really effective and lose weight with it too.
swastedcat 2 years ago
I'm going to live for ever.
w00taz 2 years ago 2
for real.
xlovenuggetx 2 years ago
lol, i didnt even knw you could have such long titles for videos.
Crazylalalalala 2 years ago 2
cyborgatise our species and go into space. Swap our biological vehicle for a more suited 1 for earth is a finite place.
have a good'n :)
TheBowlerHatGuy 3 years ago
Your videos are informative and interesting! keep making more! And your hair looks great dont worry :)
Arctura000 3 years ago 9
I don't think that aging has to do with help care or technology. It's probably more related to your intentions and your behavior towards others.
sts3234 3 years ago
what? how do you reason that?
chaos0987654321 2 years ago
I plan to live forever - so far so good!
FordCortinamk3 3 years ago 17
Best comment EVER
stdelcambre 3 years ago 2
the future is coming faster and faster. everyday things like these new iphones...people don't even think about it, it's already common place. just 20 years ago it was science fiction. the world is changing at an accelerating pace, and medicine is part of that. the deeper questions are, of course, how we as a society can deal with this technology and it's social implications. can we sustain a planet where people just don't 'age' in the natural sense?
deemilieu 3 years ago
I see a lot of people calling for "population control", that we are running out of resources and space on this planet...which is utter RUBBISH. We need to adjust how we live, and use our resources more efficiently. We can fit 20 BILLION people on this planet - do your research. A long lived population will alter our perspectives on the environment and what we want for our children and grandchildren since we will be living it. This would be the greatest thing for humanity since discovering fire.
silverhawks 2 years ago
There is so much that we just don't know. My grandparents lived into their 90's in a rural part of Lanarkshire, yet just 10 miles away you will find the average life expectancy in a city like Glasgow to be as low as 59 in some places. My grandfather liked a whisky and he smoked, it made little difference to his health. I think it is almost completely genetic. As a non-smoking ex-athlete I am 43 but I believe I will easily see the other side of 100. I've been with vitamins and DHEA.
beatityatube 3 years ago
Cont'd. My father and mother are 79 and 77respectively, and both very healthy. They both worked until retirement age but I believe their lower-middle status has a direct influence on their longevity. My parents both take vitamins and daily aspirin. As a science writer my life is much less stressful still. I believe my experiments with hormones and vitamins, and regular workouts at the gym, will directly extend my life, and quality of life. It is bith a state of mind and our whole approach.
beatityatube 3 years ago
Cont'd. In the past 2 years, I have lowered my blood pressure from a diastolic in the mid 80's to avg. 72. Simply by changing how I prepare my food. I strongly believe that the answer to a long-life with a good quality of life, is a lot simpler than most people realise. As a Scot living in Texas, I have adopted some of the better parts of that culture and rejected the less healthy ones, this seems to work well with my overall plan. I'm doing it with readily available products. Regards, David.
beatityatube 3 years ago
im 20 and im most likely going to live 4eva
mcgmode 3 years ago 4
Hello Dr. I am very interesting about the human aging now. In my opion it is very complicated area, because human body is a very complicated thing, especially, when you want to slowdown, or even to stop human's body aging. How do you think, wich will make most infuential work in stoping aging in the future (if it is possible, of course): biochemists, molecular biologists, geneticists or bioinformaticists? I'll be very thankful for the answer.
And sorry for my english... :-D
aiwo20 3 years ago
Hello dear Dr. I am very intersting about the human aging. In my opinion This must to be a very complicated area, If you want to expand human life radicaly, yes? How do you think, wich people will made most influential work in the future: biochemists, molecular biologists, geneticists or scientists from bioinformatics?
Very thank you for answers.
P.S.: sorry for my english... :-)
aiwo20 3 years ago
this is exciting stuff. I want to be a part of it some how
nvdp2002 3 years ago
Go to the gym... :-)
beatityatube 3 years ago
reduce SIR2, SCH9, & RAS2 genes in yeast, life = 6x longer. Mammal counterpart is SIRT1 to resist oxidants, store nutrients. It regulates P-genes to make less cells to fight infections. Much like HST1, no good.
orthon360 3 years ago
how do you get a mouse to live till 160? wtf? 160 years must go by first.
XxRoycexX 3 years ago
uh....the part about 160 year life span.....its 160 MOUSE years, not human years, a mouse life is much shorter than a human but when they say 160 years of life that if they did the same thing to a human what they did to the mouse: the human would live 160 years
chaos0987654321 2 years ago
Dr.,How do you know, that we understand about human body ENOUGH to stop aging? Maybe our molecular systems, from wich is made our bodies, can't to be trasformed in that systems, wich can to function forverer? And whay do you think so? And I know that gerontoligists, wich is working all the time in aging, is very critical about that...?
(.. and sorry for me english... :D)
Thank you.
aiwooo19 3 years ago
We don't know a lot about the human body yet - but we will know far more over the next 35 years. Patrick Dixon
pjvdixon 3 years ago
hello, just came across your show, I thought it was amazing! I am interested in nutrition and exercise for hoping for a slower aging process, what else can I do? All I know is to say alive until someone finds the holy grail.
antony6969 3 years ago
uh Mr. Dixon, i was just wondering but would it be too absurd of an idea that maybe "aging" is simply a genetic disease.....a flaw in the genetic code? maybe?
chaos0987654321 2 years ago
Thanks, Virgin G are doing amazing things. For more of my videos on this issue SUBSCRIBE to my next videos - press ORANGE BUTTON top RIGHT. Patrick Dixon
pjvdixon 3 years ago
also i am a subscriber of urs, i observed the video with virgin galactic...indeed a fantastic job those guys are doing and congratulations to the whole engineering team behind this project. Literally stunning
Athenianphilosopher 3 years ago
and how do u suggest this is accomplished? telomerase? immortalised cell lines and cancer exhibit this phenotype...what is ur scientific hypothesis? how do u think this can be accomplished? could u pls indicate me the biological toold u would operate with?
Athenianphilosopher 3 years ago
Thanks. Yes turning on telomerase for short time (too long risks cancers), and other targetted approaches. For more of my videos on this issue SUBSCRIBE to my next videos - press ORANGE BUTTON top left. Patrick Dixon
pjvdixon 3 years ago
I am at Imperial college if u know it in london. u suggest experiments on mice but u have to understand that although the genome is 99% similar there is a huge degree of altered difference between biochemical pathways in mice and humans. Take for example Th-IL-17 cells. Originally it was thought they did the same thing exactly. The transfer from mice to humans is a very long process. As a physician u should at least indicate that and not give ppl hope like this concrning immortality
Athenianphilosopher 3 years ago
Thanks - yes that is true. The jump from discoveries in mice to humans is always complex and tenuous. But nevertheless the fundamental cellular mechanisms of ageing seem to be relatively few in mammals. Patrick
pjvdixon 3 years ago
ageing is delightful, people worry too much about it. its fun.
mrsbrown333 4 years ago
what? aging.....is a disease.....and we will find the cure to it just as every other disease on this pathetic mudball of a planet as well as any other planet we find and colonize
chaos0987654321 2 years ago
nanotechnology is where its at.
drackule 4 years ago
Yes. Within the next 10 years we'll be able to control aging... even reverse it. Stem Cells research seems to be the Holy Grail.
Today... we can slow aging simply by following a radically reduced caloric intake... while maintaining a high level of nutrient intake (CRON).
Also, substances like Resveratrol seems to mimic Caloric Restriction.
What do you see as the answer to actually REVERSING the aging process itself?
PaulHartXYZ 4 years ago
Alteon did some interesting work in mice and rats on blood pressure. The drug permanently lowered BP and at the same time improved elasticity of the skin.
pjvdixon 4 years ago
calorie intake only works for rats. There is no scientific proof the same is true with humans.
I don't know much about the process, but telomerase is the key. Find a way to activate telomerase without increasing cancer risks and without stem cells.
Otherwise, you'll have to wait.
marcules 4 years ago
Have your heard about the discovery Geron made with the substance TA-65, which supposedly lengthens telomeres without increasing the risk of cancer?
They claim it "stops the biological clock." The compound is licensed through TA Sciences.
(Cost: A mere $24,000 annually for therapy.)
PaulHartXYZ 4 years ago
there isn't any evidence for humans - yet but many that practice this are certainly receiving some health benefits. We will have to wait many many years to verify if it works or not; I will bet that it does to a certain extent.
Add to this proper diet, exercise, aggressive supplementation add in a pinch of hope and we may live long enough to see further breakthroughs.
Bzdi138 3 years ago
"...within the next 10 years we'll be able to control aging..."
Pure speculation.
"...substances like Resveratrol seems to mimic Caloric Restriction..."
Resveratrol's bioavailability in humans is almost ZERO, owing to its rapid and extensive metabolism.
"...we can slow aging simply by following a radically reduced caloric intake..."
A radically reduced caloric intake may or may not slow
aging. It's too soon to tell.
Soulnik 4 years ago