Muscular Dystrophy Gene Therapy: ScienCentral News Video

[happinesson]

Parents would do everything to save their child's life!

[rameshanunneri04]

Is this effective for LIMB GIRDLE MUSCULAR DYSTROPHY ?i am u .remashan aged 50 .My y sister & I are LGMD patients.plse give a reply

[navdeep88thakur]

@sciencentral

so what's the progress made...plz do tell us.

[TooFreshproductions]

thank you mr chao

[cchucchy]

how did the therapy on the little boy go? was it successful?

[davinder1818]

i have mascular dystrophy and my 2 sisters also have mascular dystrophy..

[eeebop]

This was done 5 years ago. Has there been any progress, or updates since?

[sahilsally1]

Name:India Atees ayurvedic

Part used: underground stem or root. Sweet atees have more herbal quality then bitter atees.

Uses:

Its anti poisonous, used as tonic in any type of weakness, its antipyretic, can be given in powder form with honey or with water to cure fever. Its is also useful in nervous system,related problem, muscular dystrophy.

[missassyme15]

@sahilsally1 is this a treatment you are taking about. is a natural, if so can you let me know about

[chicksdigcam]

Well I am 42 now-with a v rare form of MD -plectin gene mia. First my legs, then arms now breathing is a little harder. Maby the old pump is getting down on pressure too. My 2 kids are fine [I hope] don't know how long I've got left but life is good-pretty good anyway. No use in dwelling on things so get out there and do what you can-don't let crap hold you back and you never know the research may just happen to come up trumps. I'm a bit screwed 'cos I am so rare but the common MD is close im

[faolitaruna]

I assume they are talking about Duchenne's muscular dystrophy,. Everyone who have been mobile at the boy's age (8-years) have some other disease. Especially those who have Becker's muscular dystrophy (it's alot of milder), please shut up. It's x-linked disease, so your mothers, sisters or girlfrends don't suffer from it.

Stephen Hawkinks or any celebrity doesn't have it. There are plenty simmilar disease.

[golla1432]

Its also autosomal ressessive and autosomal dominant, not only x linked.

[faolitaruna]

It is one of best described genetic diseases. Dystrophin is giant protein and i can assure You its gene is certainly on X chromosome. You don't have any source of this claim, because You even didn't bother to open a book.

[golla1432]

Autosomal means it can be passes on to any one of the 22 NON SEX chromosomes. Which means its still a GENETIC DISEASE. But no it is not only X linked. According to the National Institute of Diseases.

[faolitaruna]

You are unique in Your vision of huge gene, which location cannot be determined. Every halfwit can find book about genetic diseases. In there he can find good explanation of Duchene Muscular Dystrophy. This is something which people are understanding for about hundred years.

You are an idiot.

I was responding to some confused soul, who could distinguish between muscular diseases and thought that somebody in his/her family or even Stephen Hawking has DMD.

[erinberinvicky]

my dads 50 with md

[RingoStarr888]

My boyfriend Terry has Muscular Dystrophy and it worries me. People with MD sleep a lot. I wish, hope, and pray they will find a cure for Muscular Dystrophy soon!!

[sweettrav20]

i am 23, and i dont sleep alot. i sometimes stay up 24 hours +. i wouldnt worry to much.

[SkinnerRichard]

This is freaking cool! Just imagine, gene therapy in the future could help cure many diseases, and perhaps enhance our genome! we could control our evolutionary path! WOOT

[Pitraptor]

Yes, it holds the most promise in repairing genetic mutations causing diseases like muscular dystrophy and so many more other diseases. But it's the mindset that we can control our evolution and enhance ourselves that has blocked this road to preventing loss of life and destruction of quality of living for years. It's unfortunate, because if people weren't so greedy the progress on this field of medicine could have been so much greater than it is.

[F1RE2WATER]

Were the results positive?

[jcishere08]

well I can say that the video is lying about MD. Because I have it and Im 27 years old. People with MD DO NOT LIVE UP TO 25!!! I myself am living proof of the matter!

[CapriceK]

yeah, the oldest guy was 55! I knew a guy who made it to 40. I'm 21 and my brother is 23, and we're still pretty mobile, both in wheelchairs but can still lean forward unassisted and stuff. Not even on oxygen or anything. Kind of at the stage most 13-14 year olds get. I did get cardiomyopathy last year but that's levelled out now.

[jcishere08]

sweet

[roidroid]

the video says "usually" die by the age of 25.

there's no lie

[jcishere08]

i have known many ppl that r over 25 and ok.

[SkinnerRichard]

Doesn't Stephen Hawking have muscular dystrophy? He's like, in his 60's.

[sweettrav20]

i believe they mean some types of MD. there are MANY types. there are some in there 60's and 70's with it. the AVG overall age is 40.

[Pitraptor]

I believe his views on the age limit before real progress was made for DMD, DMD is a particularly lethal form that targets the heart. I was very thankful to hear all I had was limbgirdle, better to lose walking and lifting than to live the life DMD results in.

[Genetherapynet]

Very nice, hopefully it will work for a long time.

Check more gene therapy news at Gene Therapy Net

[zaction]

Also check out the ASGT site for news

[roidroid]

this is amazing, one injection will be able to make you glow green.

this would be a good prank to pull on someone, and raise awareness of the power of gene therapy.

[zaction]

It's called the EGFP gene (Enhanced Green Fluorescent Protein) Pretty cool :) I have worked with it a lot. Also, have worked with the guy mentioned here. Xiao Xiao. Very cutting edge stuff. I have been working on AON therapy for DMD. It has great potential. It works in the MdxE23 mouse. (Exon 23 mutation). I have developed DNA vectors for other exons (human ones). Exon 43,45,50,51,53. I hope these are a huge help some day.

[proguitarplayer2005]

Hi my mom has MD i might get it to we dont know yet im 13 and still dont have it i hope i never do but please tell me if theres a cure soon i mean i might die from the disease

[MolitvaSrb]

quite dumb*

[zaction]

Dumb!? That's mature. I am doing some collaboration with Xiao Xiao and the man is no dummy. My boss is Qi Long Lu and he is world renowned in DMD and LGMD research. Maybe you could tell me why you think it is dumb?

[greatbritain2k3]

molitva was correcting the spelling of a part of his previous post (although there were a lot of other spelling mistakes in it)

[MolitvaSrb]

im getting sober and im beginnig to think waht i sad is cuite dumb but i like tio drink, i have 20 years and i can still waljk i know i never gonna have girlfriend and i am n00b, i also think i have social anxiety disorder coz im afarid to talk to people, or maybie am just spoiled kid!!!!!

[MolitvaSrb]

Hey I have a question I also have MD I dunno what cinde of it is, and I like to know can we drink alcohol my dad dont let me drink coz 1 doctor sad people like me sould not drink coz it make us even weaker, but I [personaly think we should drink coz our life is shit, and drinking make us hapy, like evry 1 els who have a bad live , and im drunk atm

[rambohs]

Have A FEW jars man. I have many friends with MD LIKE ME AND IT DOES YOU NO HARM AT ALL. it's you life.

[historyforamir]

Hi I have BMD, I am 17, and i am about to lose the ability to walk in few months.

I think of alcohol too, but i believe it will wreck my life , so i sholud handle all the difficulties without alcohol.

DONT DRINK, BROTHER!!!!!

[blee20]

I myself have Limb Girdle Muscular Dystrophy and i am happy to see this

[zaction]

Hello! I am working hard on LGMD and really feel there is great hope for treatment. My lab was started by a very wealthy man who's granddaughter has LGMD. Do you know which mutation you have in your FKRP gene? I can find the latest info for you if you like. Sincerely, Allen

[chelas00]

Hey zaction, I also have LGMD 2D, do you know where i can find the latest news or updates about my disease. How far do yo see stem cell therapy

[Freakbox]

I noticed this video is now a bit old.

I am frustrated why this has not already been worked out.. and rediculous wars (and money for wars) take priority in US.

Antisense? virus transport methods for carrying healing genes?

Thx for vid anyhow- very intrsting.

[Luchik33]

nice to hear this..hopefully one day a cure will be invented for all dystrophies..i have FSHD one

[KuraiGaka]

Hello- I would like to know more info about how much fundings go into MD per annum and how much charities are able to fund for it. I'm making a movie featuring MD- can you give any info?

[sciencentral]

I would check with the Muscular Dystrophy Association, (mdausa-dot-org).

[KuraiGaka]

Thanks!

[smartplanet]

Hy, I would like to know why this video's embedding feature is disabled.

[sciencentral]

It's now enabled!

[xbald8]

i thought i was the only one on here that had it.its nice to know people like me still do stuff that normal people can do.i hope this works.

[zaction]

Bless all of you folks who suffer. I am working hard on the disease and feel good that we will fins treatments for the numerous versions of DMD, LGMD, BMD, etc. I just got back from a gene therapy conference in Seattle Wash. and LOTS of progress if being made. Please hold on to hope.

[historyforamir]

Hi! i have BMD, i am 17 years old,i am about to lose the ability to walk soon.

Can you give some advise about treatment. now i only take Steroids (prednisone), Creatine and Glutamine. This helps but Steroids are quite harmfull.Tell me what can i do??? !!!

[zaction]

Hello! You have a very strong will and a good attitude. This is the best thing you can do to be honest. Having a good outlook can work more wonders than any drug can. As far as treatments go, I am not a doc, so I can't really comment as I am not qualified to make those kind of assesments. Creatine, I hear is a good option. We are learning so much and will find help in the near future I feel. Hang on! :)

[Koeny]

i have dystrophy and i'm happy to see this

[EhtOtam]

Do you know any more about the findings on this video or who the organization is who is doing these studies?

I have an avid intrest in these specific studies.

[sciencentral]

The Muscular Dystrophy Association (mdausa-dot-org) funded the study. You can read more from ScienCentral at tinyurl-dot-com/ybfnug .