The MAP-Kinase (MAPK) signalling pathway

[petercourt]

This is brilliant, just what I was looking for! Thanks.

[pedromigelab]

And Integration with cilindrical shells is easier than this - stop prettending you're a genious, boy ;) Integration level 3 - this is Biochemistry level 0,01 x)

[Appclypse]

@pedromigelab You lot need to stop your dick meassuring haha

[kommienzuspadt]

@Appclypse He's a medical student, that seems to be their principle occupation (Besides complaining about how busy they are and how hard life is, wah wah wah).

There are a disturbing amount of mental children on youtube...

[Appclypse]

@kommienzuspadt Yeah i hear that, superiority complex, i see it with people on my course too. Seem to think because we do a science degree that suddenly any other degree has 0 value. Particularly pisses me off when they go after musicians or artists claiming there skills to be useless. Absolute arrogance.

[kommienzuspadt]

@pedromigelab You misspelled three very basic words. Please consider brushing up in your mastery of the english language before you go handing out condescending remarks to other people. Your mistakes would be shameful for most middle schoolers.

[pedromigelab]

FUCK x-S I'm a meds student and I've an exam in one hour from now of Biochemistry - I curse joshua :-P - Sun, when you really have to learn this you'll not love it as now you apparently do - please, PLEASE ENJOY HIGHSCHOOL ahah I'm going crazy x-/ thanks for the video Onkoview, it was very good :)

[zerle12]

Thank you so much! My fiance needs this so much for his exam =D

[CexyNariko]

Thank You so much!!!

[joshua99999999]

I'm nearly 14 and this is so confusing xD -

I want to learn about this in the future =) - Might take Biochemistry for University - (for college do an A-Level on 3 subjects :P )

[delic619]

@joshua99999999 Awesome man! I bet you are heaps good at reading chapter books and long division? I'm sure you can tell me what an atom is made of too?!!!

[joshua99999999]

@delic619 No need to get rude... I was only saying what I wanted to do... Besides... Fuck you, No I'm doing Integration with cylindrical shells...

[delic619]

@joshua99999999 Pretty cool story bro. Good call though, biochemistry would probably have been too hard anyway...

[GronTheMighty]

Although the topic of my exam today is the effect of mutations in the KRAS gene which inhibits response to EGFR-supressing monoclonal antibodies, this animation still was rather helpful in ensuring that my understanding of the general pathway in question is intact and functional - Thanks to the makers/uploader <3

[Gottfried2210]

I like how GAP keeps getting a boner....and trying to stick it to RAS....

But seriously, this video is FANTASTIC, its MIND BLASTING, it makes me

cum heavily everytime i watch it....

[delic619]

@Gottfried2210 dude, i reckon if you explain signal transduction pathways that way in an exam, you'll get bonus marks...

[tankx2]

This video is absolutely brilliant.. my lecturer is Italian and its very difficult to tell what she is saying.. this has saved my life!

[Lauramble]

@tankx2 I really hope this comes up on the exam now

[isthis1t]

This is going to come into use in my final tomorrow. Thank you!

[skocijan]

GAP cant get it in when RAS is sick

[shreds941]

lmao!  @ 4:10

[rbrtchng]

This will save me on my midterm tomorrow

[destiny0001k]

sos = son of sevenless a mutant in eye development in drosophila.

Thanks alot it is very helpful!!

[1006Will]

thank you very much!!!

[adaptationmec]

very nice and useful. thanks alot.

[adaptationmec]

very nice and useful. thanks alot.

[kappasr]

Thanks, it's very useful and clear =)

[smiley7138]

Wonderful.. Thanx..:)

[whitebutterflySR]

thanks, going straight to journals is pretty baffling when u dont understand the basics - so this is very useful

[paulioyeuh]

won't the original receptor still be turned on? and then it can activate Ras-GDP again.

[1uPmExIcAn]

@paulioyeuh

the original receptor is only activated with bound ligands and loses affinity for them afterwards. So no, the receptor is not activated all the time.

[paulioyeuh]

@1uPmExIcAn why does it lose affinity?

[redSHIFT69]

SOS = son of sam ?

idk. i m in med school and have a test on this stuff tomorrow. 1 of 100 cascades i have to remember....on another note. how many biochemists does it take to change a light bulb?

[redSHIFT69]

go RAS go!

[imagen1985]

this video is so good!!!congratulations and thanks!!!

[kataka88]

thank Allah for this video

may god bless u

[Muuip]

Thank you! very well explained.

[meme2342]

Very clear and (more improtantly) memorable! I especially like the bit at the end on tumorigenisis.

[kuthro]

thank you. a lifesaving study video.