Warfarin (Coumadin): Most Important Points for USMLE

[TripleXconscience]

wow this guys very helpful, i thank you.

[NekoInKimono]

Thanks for the video. I have FVL and I can tell you that unfortunately doctors tend to not spend time explaining stuff like this to patients, so it's nice to find an informative video like this. I'd love to know more about this new drug Pradaxa, but I guess it's too early for information to be readily available.

[Allibaby78]

Major bleeds are defined as intraorbital, intracranial, retroperitoneal or muscular bleeding causing compartment syndrome. Any acute bleeding with BP less than 90 mmHg, oliguria or Hb drop to less than 9 g/l, also count as major bleeding episodes and require aggressive reversal of the coagulopathy with vitamin K, stopping warfarin and prothrombin complex concentrate or fresh frozen plasma (FFP).

[Allibaby78]

In monitoring, a conjunctival bleed is defined as a minor bleed, and current guidelines suggest that oral or IV vitamin K together with the omission of warfarin, is the treatment of choice. Local guidelines should also be available.

One must always weigh up the risks and benefits of reversing the anticoagulation. The patient described is at low risk if the warfarin induced coagulopathy is reversed. There is no suggestion from the ECG and the haemodynamic status that there is pulmonary embolus.

[CoumadinRapSong]

Search for "Coumadin Rap Song" for an alternative form of patient education for this very important anticoagulant.

[curemsa]

A few months after receiving a plasma transfusion to briefly thicken moms blood(after being on coumadin for a long time) for feeding tube insertion she received a ct scan showing a giant mass in her abdomen. They became quite certain she had Ovarian Cancer. I'm beginning to wonder if it could be a complication of long term coumadin therapy. I've read that ovarian hemorrhage can be a consequence. I have been reading about ovarian cancer also being a consequence of Vitamin K deficiency.

[kessuman]

You are awesome. God bless.

[idonotneedanidforyou]

thanks for the vids. Very good!

[dhruvpanchal]

thanks. I did learn a few new things.

[kingCRAM11]

TY ur awsome

[nakedphone]

Awesome.Thanks a lot.Can you talk about the loading dose and maintenance dose as well, and indications of warfarin in AF patients based on CHAD2 score.

Thanks

[hodoli]

maybe it might be better to clarify that warfarin does not actually oxidize vitamin k. Rather it blocks epoxide reductase whose function is to oxidize vitamin k, thereby leaving vitamin k in its reduced form, unable to gamma carboxylate factors II, VII, IX, Protein C and S.

[rare1walking]

Excessive bleeding and gangrene are the two most serious problems with this poison. Leafy greens, apple juice, etc. -the list is long-of foods with Vitamin K not to be taken. 50% of those over 50 are on this poison because of the sales job of the medical doctors, according to some info. Toxic!

[o2demand]

helpful clinical videos for USMLE prep

website: o2demand

[dave19804]

There is a 48-72 hour delay for the action of warfarin to kick in.

[csabeg]

lots of important information in short.thank you

[Erinduriel]

thankyou!