Good video, but there's another aspect to digitialis' effect on the heart that's worth mentioning - namely the fact that sodium accumulation in the cell changes the membrane potential significantly - this causes the NCX to reverse: it starts pumping sodium out, and Ca in, further increasing the strength of contraction.
Thanks for these videos they are brilliant! One question sorry I'm not quite getting the name of the Ca receptors on the sarcoplasmic reticulum.. any help?
@jaggysnake3 They're the RyR receptor (ryanodine). They're connected to a foot protein which mechanically opens a 'gate' on the sarcoplasmic reticulum, allowing for the eflux of Ca++ into the sarcoplasm.
Wow. Thank you so much for taking the time to do this! You're amazing! I actually really understand the whole process and concept instead of simply trying to memorize the terms.
thanks so much , i love the cardiovascular system except this as i didnt use to understand it, now im rock in it because of you...god bless so amazing
1) Does SA and AV nodes have NCX, membrane bound calcium channel and membrane bound sodium/potassium channels(0:40min---1:00min)?
2) According to action potential graphs of SA node and cardiomyocytes, when does NCX, membrane bound calcium channel and membrane bound sodium/potassium channels is active?
hey man, thanks! you really helped me out for my test tomo, I couldn't understand my professor nor the book. but thanks to you I think i might actually pull off a good grade!
Thank you so much. I'm in my first year of medical school, and I find my physio professor very confusing. Your teaching style and drawings are very easy to follow. Thank you for taking the time to make the videos and sharing them!
jiji, creo que ya le estas pidiendo demasiado conoce del tema sabe explicar, y además pinta! no creo que hable español (triste), pídele ayuda a compañero que sepa ingles, o buscalo en overstream, quizás alguien le ha puesto subtitulos ahí, yo te traduciría algo pero esta como que largito el cuento y no le cojo el acento algunas veces, además no se cuanto confies en mi, si lo deseas dime que parte exactamente no entiendes y yo te lo digo ^^
walid! im sooooo in love with the way you teach! you married? haha only joking :) but seriously thank you so much...wanna do a cardio pharm series? pleeeeeeease
thank you !
rottingapplez 4 days ago
Asalamwalaikum
TheSeanSimpson 1 month ago
thanks
dellinspiron17200 2 months ago
This has been flagged as spam show
You have cleared up the fog that has existed for two days!! EXCELLENT!
sacto1036 3 months ago
You have cleared up the fog that has existed for two days!! EXCELLENT!
sacto1036 3 months ago
Thanks a ton! Good videos! Thanks for sharing your knowledge with others.
HondaSolutions 3 months ago
Good video, but there's another aspect to digitialis' effect on the heart that's worth mentioning - namely the fact that sodium accumulation in the cell changes the membrane potential significantly - this causes the NCX to reverse: it starts pumping sodium out, and Ca in, further increasing the strength of contraction.
Secretus 3 months ago
Thanks for the inclusion of drug action! I'm a first year pharmacy student and this was really helpful in my physio course!
mhaas88 4 months ago
Amazing Skill!! Wish I had you teaching me during my Med school carriar :-) Keep up the great work my friend!!
eranbw 4 months ago
Thank you so much for these videos. Your teaching style and drawings are straightforward and incredibly helpful. I cannot thank you enough!
triplea309 4 months ago in playlist heart physiology and cardiac action potential
I love this guy. I'm going for my phd in genetics, so this type of physiology is not normally my area.
(I had one of only two A's out of fifty students in my last A&P class. So thanks for helping me understand this stuff better.)
SinistralMaternalEfc 9 months ago
how does K+ increase in ecf effect the heart?
nakeya52 9 months ago
Thanks for these videos they are brilliant! One question sorry I'm not quite getting the name of the Ca receptors on the sarcoplasmic reticulum.. any help?
jaggysnake3 10 months ago
@jaggysnake3 They're the RyR receptor (ryanodine). They're connected to a foot protein which mechanically opens a 'gate' on the sarcoplasmic reticulum, allowing for the eflux of Ca++ into the sarcoplasm.
knot4reel91 9 months ago
Your videos scored me a D in my first year uni exam! I love you!
BlackGypoMagic 10 months ago
Thank you sO soO much!! You are amazingggg! =)
Muska5 1 year ago
i am your number fan, you videos are amazing, Well done, you ahve made learning fun for me and well explained. Please do add more videos
bsms2519 1 year ago
NCX goes into reverse mode in the presence of high cytosolic Na, thus pumping ca into the myocyte.
monkeyfizzel 1 year ago
This is the best!!!!!!!!! Thanks.
lajames1144 1 year ago
thank you a lot! from italy!
bboyjojo89 1 year ago
great job.. thanx
almofeed87 1 year ago
Excellent job, very clear to understand. Thanks a ton
patprathu 1 year ago
Wow. Thank you so much for taking the time to do this! You're amazing! I actually really understand the whole process and concept instead of simply trying to memorize the terms.
nuhakadri 1 year ago
im gonna favor it so hard
lbreakzl 1 year ago
great video!
hishoooooooooooooooo 1 year ago
thanx :D
Haneeno86 1 year ago
Thanks a lot, very good explanations, easy to understand! Thank you very much...
kardiokonsult 1 year ago
Excellent series! Thanks for doing these videos. They have been a great help for my critical care!
whittvet 1 year ago 2
Excellent Job.... !!!
double thumbs up !
umar379 2 years ago 2
use some COLOR!!!!
zubery 2 years ago
thanks so much , i love the cardiovascular system except this as i didnt use to understand it, now im rock in it because of you...god bless so amazing
mesnagayama 2 years ago
This is truely amazing teaching, very clear and understandable demonstrations of complex mechanisms.
nenenede 2 years ago 3
Brilliant stuff I love all your tutorials - gifted teacher! Thanks
waltzingfrog 2 years ago 2
u are amazing.....my instutor is good but this is the icing on the cake.....i get it now.
thank u
sleepyeyes163 2 years ago
Your amazing!
ELlSSA 2 years ago
Great job Walid. I want to eventually be in your position during college. I honestly understand everything you've said clearly.
vr00m123 3 years ago
Thanks for the painstaking efforts. I appreciate the detail. You're a good man!
scroopit 3 years ago 14
1) Does SA and AV nodes have NCX, membrane bound calcium channel and membrane bound sodium/potassium channels(0:40min---1:00min)?
2) According to action potential graphs of SA node and cardiomyocytes, when does NCX, membrane bound calcium channel and membrane bound sodium/potassium channels is active?
3) When does phospholambin is active?
I hope i am not very confusing or confused...
1reem8 3 years ago
amazing, you are a great teacher, you've help me so much!
heidilanebostick 3 years ago
hey man, thanks! you really helped me out for my test tomo, I couldn't understand my professor nor the book. but thanks to you I think i might actually pull off a good grade!
major thanks, major props!!!
gfxmaker 3 years ago
now i become a smart girl because of your video, ahaha....
liaaa90 3 years ago
Thank You sooooooooo much
you really made my day!!!!
Sleepless0in0Riyadh 3 years ago
Thank you so much. I'm in my first year of medical school, and I find my physio professor very confusing. Your teaching style and drawings are very easy to follow. Thank you for taking the time to make the videos and sharing them!
BackFromTheWild 3 years ago 26
@BackFromTheWild I am where you are now, in exactly the same position you were it seems! :)
TheSeanSimpson 1 month ago
Comment removed
cookievoila 5 days ago
i love your videos!! thanks so much...now i understand~ it helped me heaps!
ratrat 3 years ago
good job...!
psjeevitha 3 years ago
pleeeeeeeeaaaaaasssssseeeeeeeee
in spanish am chilean i need hell me
xnegritapf 3 years ago
jiji, creo que ya le estas pidiendo demasiado conoce del tema sabe explicar, y además pinta! no creo que hable español (triste), pídele ayuda a compañero que sepa ingles, o buscalo en overstream, quizás alguien le ha puesto subtitulos ahí, yo te traduciría algo pero esta como que largito el cuento y no le cojo el acento algunas veces, además no se cuanto confies en mi, si lo deseas dime que parte exactamente no entiendes y yo te lo digo ^^
lpag119 3 years ago
thanks so much, you have an incredible way to teach.
you have helped me a lot to understand all these subjects.
mayela777 3 years ago
walid! im sooooo in love with the way you teach! you married? haha only joking :) but seriously thank you so much...wanna do a cardio pharm series? pleeeeeeease
donna777lynn 3 years ago
salam! sick work on all of dem bruv. uve helped me propa ...... :)
mcbukola 3 years ago
Thanks bro. your videos are really helpful. Thumps up for you.
03338259007 4 years ago 2