Welcome to Foldit!!

[E450AMD]

Where I can download this game? I can't find this game on Internet.

[maglight117]

@E450AMD the site is fold.it

[Ferblox12]

I love this game. It makes me feel smart... or am I really that smart?

[JesseVictors]

How about you guys run Folding@home on your systems while you fool with Foldit at the same time? That seems like the optimal scientific setup to me :D

[afterbirthtycoon]

If I was able to figure out Dwarf Fortress, I can definitely cure HIV.

[TopShelfization]

@afterbirthtycoon it's the truth, us gamers, we have purpose in RL now! hahah

[TheGeckoNinja]

as revolutionary as this is and helpful to curing diseases i am not smart enough to play cause its way to damn complicated XD

[epicdista]

Well, I can count to ten.

[ReeferReas]

You sound hot

[ohperoqueesesto]

next step: cure sida

[apdjbs]

It would be interesting to see what would occur if the 7.3 million people under correctional supervision in the U.S. were to have access to this project, and perhaps given some additional incentive. Even 1% would be a large number of time dedicated individuals.

There will be obstacles to overcome, but everything to gain. Just brainstorming a possibility. Think about it. Pass it along.

[Jdawg1798]

Y dont they do this all the time... It took scientists tens of years while it took gamers tens of days

[NPKing123]

@Jdawg1798 because a lot of people still underestimate how powerful crowd sourcing is. Nothing can truly rival the combined efforts of thousands of motivated people when trying to solve a problem. That said, in 10 years they got it to a point where the people who played the game had a pretty good starting point.

[Eziomaster]

where do i download this?!

[trudbol]

@Eziomaster Just Google "foldit"

[skatemonkey00]

Wooow thats awesome...lol

[Mustang88166]

In other words, you need to be a genius to sort it out... Cool, cool game. Right.

[thadx123]

Scientists:10 years no luck.

[thadx123]

This game possibly raised the chance of finding a cure for AIDS.

[Vacremon]

I dont understand why people would want to play this

[sobored671]

ACHIEVEMENT UNLOCKED!: CURED AIDS!

[citrons666]

@sobored671 YES!

[miracattable1]

Love the game, structure, brain-training, and actually working with something usable in real time.

[ShiftyShifts]

Now you're thinking with proteins.

[MidnightRedemption]

i cant imagine gamers talking this to a forum

[01newuser]

Very cool, I love the idea!

[mario4ever1000]

hmm i wonder who will complete it first me or science teacher PLACE YOUR BETS EVERYONE HE IS GOIN DOWN

[mario4ever1000]

my doc reccomended 10 cc's of this daily so i decided to check it out and its amazing gamers can figure out a disease in 3 days what took scientists 10 years GAMERS UNITE

[kenkenha824]

What will be happened if Foldit provides thge structure of T-virus?

[ShadowsChi]

@kenkenha824 Time to go huntin guns, bits and bobs

[TheGeckoNinja]

@kenkenha824 then get yo shotguns >:D

[SpyengoEen]

I didn't understand ANYthing. What do you do in this game? It's so abstract.

[itachiitachi1946]

i soleved 22 puzzles today(there r 38 or 42.idk how many puzzles they r but w/e)in 4-4,5 hours.this game is so addictive.i wanna solve ALL puzzles and achieve higest score asap.nazi zombies was the main game i was playing evryday.now ill be playing nazi zombies AND foldit.(i dont care about sciense or hiv.all i want is to beat the fold it game.but if ssince its helping sciense then its good.)

[RickAble14]

they should make more games like this :)

[DontMissVideos]

How come when I try to download "Foldit" it is saying that "This program is not commonly downloaded and could harm your computer." Why is that? I have Windows Vista 32 bit

[Arxces]

People playing this game have managed to fold proteins supercomputers fail at folding. Amazing what you can do when you turn it into a fun activity.

[theshocktart]

There are no 'portals'...but since its 'for science'... i'll give it a try...

[MysteriousStrangerxX]

Due to this they broke aids puzzle yay!! It was on yahoo mail!

[digitalpenink]

Congratulations, you and people like you solved the puzzle!

[JayJayAbels]

This game should be on Xbox Live. I'm not kidding at all. Give any Halo champion or COD elite player this game and they could actually change the world. They are extremely competitive.

Of course some douche will hack the lobby and probably infect everyone with a trojan virus but meh whatever. lol

[Sushincorporated]

Show me your tits!!!!

[JayJayAbels]

@Sushincorporated Yeah that's helpful.

[Sushincorporated]

@JayJayAbels Lets not pretend you dont want to see them either! :}

[ebrum2010]

I wonder what the guy who said "ROFLMAO" in response to "you are helping real science by playing the game!" thinks now that players have helped pave the way to a more effective AIDS treatment? Maybe he's hoping for a stupidity cure?

[nol50000]

Lol, There are people who sleep 8 hours a week(Or not at all), The rest of the time is playing games. I hope those gamers find this!

[xaberd22]

That is so fricking amazing! :D

[Shadowtrollz]

Trophy unlocked: cure aids

[jetaimemina]

I've half expected her to start yelling "snake snake snake snake".

[maidwithluv]

wow, everything can turn into a game...so do you get any prizes for curing cancer ? lmao

[deppravacion]

@maidwithluv if you consider the life of your family friends and humans alike a prize then, yes, you get a prize for curing cancer.

[blolo8]

Hey guys, players may have found a cure to AIDS !!! I'm not joking, look on Gamespot!

[ERTLPFM]

how about MineIt : interactive bitcoin mining?

[quaditz]

This was a triumph! I'm making a note here, HUGE SUCCESS! *sing*

[DarkExternalHeart]

@quaditz It's hard to overstate my satisfaction.

[PointyTailofSatan]

Unfortunately my latent origami skills keep making everything come out looking like a small bird.

[Javagui21]

this game is for high school students not biology/chemistry majors in college.

[vettefreak90]

@Javagui21 who cares who's playing it, as long as they're contributing.

[EightyBrains]

SCIENCE

[WallaceRoseVincent]

Thanks for the best explanation of the game I have ever listen to.

[Spectre426]

I suppose it would help to be a biologist to fully understand how to do this efficiently. Physicists don't often manually fold proteins >_>

[Mal3volution]

fucking lame

[t5239857289578947594]

This looks soo awesome.I see great potential for medical science.

[pcgeekman]

anyone have a mirror? their site is down.

[PhotoCityGame]

@pcgeekman I heard that the cooling for the foldit servers is busted, and that's why the site is down right now :(

[roidroid]

@pcgeekman it's getting slashdotted coz of all of the recent publicity surrounding the publication in the journal Nature.

[PhyOSPhyOS]

@pcgeekman Refresh it.

[jhtrico1850]

This thing kicks my ass. Also, I like these graphics vs the ones I have...

[Hazzard0]

Whatever nerdgirl!

[mentor291]

what is this :D?

[Falco98]

Achievement unlocked: Cured Cancer!

[penquinftw]

rofl. best youtube comment ever.

[kinkoblast]

Heh, yes... but it's possible that insights will be made that lead to it. The swarm was pretty much equal in ability, with much worse tools, to the pros, in 08... give it some time for strategy to develop, and the game is getting better tools all the time...

It starts to look likely that some aha moment will take place.

[kingdavidjapan]

@Falco98 yaay ^^

[Sudstah]

@Falco98 LMFAO

[P5ychoRaz]

@Falco98 Someone just managed to unravel a complicated HIV-like enzyme that scientists have puzzled over for a decade. They figured it out in three weeks flat, too. Thanks to the efforts of the Foldit community, scientists potentially have greater insight on the monomeric protease enzyme, which is in the same family as HIV. This could allow for new treatments. The findings have been published in the journal Nature Structural & Molecular Biology.

[doobie7777]

@P5ychoRaz "While the open time frame for creating the structure online was 3 weeks, according to MSNBC the correct answer was found in just 10 days."

[CCPnoob]

the great thing is - youi are helping real science by playing the game!

[Hotdogbunker]

Thanks, I needed that little extra intro!

[frokenfrost]

I play this game and can inform that the environment is welcoming towards new players, so it is really easy to learn. Questions are always answered! And the people are from all time zones with the most different of backgrounds, too, so all it takes is a little patience in the beginning.

[Fronika]

Too clever for me and for most ordinary people too, I imagine.

[marmuhlade]

Not really, it's basically just moving stuff around. You get used to how the protein is optimized after a bit, I assume.

[42foxfire]

How utterly fascinating! Brilliant! Old as I am, I may try it ;-)

[FozIber]

Let me see what I can do. Deep interesting.

[anonymees]

I tried earlier in the development and couldn't really get into it. I didn't seem to be able to make any progress. Maybe I'll try it again now.

[MishaVargas]

I bet this game would look great in 3-D.

[pikmindoctor]

errr- I think it probably is in 3D but using cell-shading. Just like in Zelda: The Wind Waker.

I like the idea of this game - kinda reminds me of that crappy 80s sci-fi film where there's these arcade machines that play a space-shooter game that secretly uploads the results to a network to find the best fighter pilot!

[MishaVargas]

Ah, I should have been more specific. I think this program could benefit from being displayed so one can use old fashioned color filter glasses to see it in true 3-D.

[pikmindoctor]

oh ok - yea I'm so used to calling this sort of thing '3D'! - yea 3D glasses would be good - in fact I'd like to see some mainstream games try experimenting with 3D - perhaps as an option you can turn on and off.

Only trouble of course is that the whole scene would have to be rendered once for your left eye and again for your right - so the GPU could have twice as much work to do. - but it should still be a great feature for those with powerful enough PCs.

[MishaVargas]

Only other big downside to using 3-D is that you lose the color. There is a better technique for doing 3-D (polarized light & glasses), but it can't be done on a standard computer screen.

Ah well, I'm just a dreamer.

[Phonolith303]

@MishaVargas:

Now you can, using a 120Hz TFT display.

[armyvisual]

You wouldn't have to render separate scenes at once.

Check out 'head tracking' here on youtube. It's very interesting and could add more literal dimension to games and applications.

[pikmindoctor]

WOW!

That's a very clever trick!

It certainly looks 3D, although I don't suppose it will 'feel' 3D in the same way 3D goggles do because your brain isn't working out depth perception as well as it would if you had a separate image for each eye, but in a way this is better than 'proper' 3D, because you get to look around stuff, and it does kinda look like things are coming out of the screen anyway - so I guess this is the best solution!

[frankbraker]

@pikmindoctor I've used older 3D goggles with some videogames (they flash left frame and right frame using an LCD to block the alternating frames between eyes) years ago, and the effect was great. I wouldn't be surprised if you could play FoldIt using similar goggles, since the goggles are tied to the video card, and work with any 3D game.

[indypunx]

Everything coming out of rosetta has been fantastic and this is a really brilliant idea. I used some of these massive distributed computational systems in my protein design and research and it really helped figure things out! Thanks for all your hard work on this project.

[sirenbrian]

I was hoping you'd show how to get 9600+ on this puzzle :) I'm stuck in the 9200 area.

[aromatichydrocarbons]

hey man, at least you're OVER 9000!!!!!!

[kaufmansarah]

sweet

[Igorism22]

Awesome stuff.