Opie & Anthony: Best of...2girls1cup Reactions with Kevin Smith, Jim Jeffries, Bill Burr, and Others

[izzymarieh1984]

I wanna see bill clinton's reaction. lol

[nickdesroches89]

and lil yimmy has a boner...

[dogshittaco24]

When Jim Norton said that thing about jerking off to bizarre shit, I DIED!!!! XD

[AUSROTTENY2K]

3:40 7:50 lol

[JDAtTheDriveIn]

Once again, Smith says it best when he spoke to Bill Burr;

"It's the one video clip that will simultaneously ruin and re-enforce your faith in humanity."

[Kitchinsink3]

You guys have the best radio...oh my goodness gracious.

[BatALash]

Adam's reaction was hilarious. That sudden "NO!"

[ConnDevi88]

I want to see Howie Mandell's reaction

[dagothwit]

You guys have the best radio show...oh my goodness.

[YoeriYoeri]

LOL jim jeffries is laughing his fucking brains out HAHAAH

[justin39640]

@YoeriYoeri Jim Jeffries laugh is the best lol.

He was great last weekend in Bayshore NY.

[Slikrik1212]

Love how Jim Jeffries is in hysterics the whole time!!..LOL! he absolutely loved it. Would nominate '2 girls 1 cup' for an oscar if he could.

[oyster43]

Chocolate mousse enema's doesn't make it any easier to watch.

[rocker816]

i think anyone could reenact two girls one cup just because we've all heard the details in these reactions..

[rocker816]

do you think 2 girls one cup will be in a text book in sociology? i think it will.

[bpsmith1979]

Jim Jeffries - Best 2 girls 1 cup reaction EVER! Also, Vos sounds like he's getting waterboarded.

[ContraBoi]

2girls1cup was MADE for the Opie and Anthony show!

[stuartstratford]

his laugh is the best



[czor1810]

I love during the D.L. part his friend says "you guys have the best radio show.... OH MY GOODNESS" haha

[johnclavis]

D.L. Hughley is a faggot.

[mazakiel]

@johnclavis How is he a fag?

[johnclavis]

@mazakiel He sucks cock and takes it up the ass, doesn't he?

[mazakiel]

@johnclavis Idk have you fucked him? Are you two gay lovers?

[johnclavis]

@mazakiel I'm afraid I'm not at liberty to say. Let's just say the "D.L" doesn't stand for "Double Length"...

[tedatlas]

"okay, y'all can quit it now" lol

[NeroTheAtheist]

I think Jim's reaction was the funniest. He was like Oh OHH aahahahahha. lol

[FenrirLupei]

Probably been mentioned about a dozen or so times, but in 2G1C it's not "shit" the girl had an enema and then had soft-serve chocolate icecream put into her anus and proceeded to press it out. So, still gross, but not AS gross as it seems.

Swap.avi however... Can traumatize Vietnam veterans.

[JESUSTONIC]

that may well be but the puking thing is still gross

[invitationofchaos]

im sorry but comparing swap.avi to this is like comparing a supernova to a balloon popping

[EricLynchSucks]

you dont have bob kelly on here? shame on you!

[jfoughe]

Check out my channel, Bob's in there.

[gnarkill87]

@EricLynchSucks bob kelly's reaction is so priceless it deserved its own video.

[Godzilla00X]

haha this is great

[johnclavis]

I love that O&A discovered 2G1C with Kevin Smith.

Great compilation. Thanks a lot!

[RaidenTheAlmighty]

2girls1cup is a real surreal fucking video. It is so far removed from the normal spectrum of human thought that most people wouldnt even consider that as an event. Puking shit into another person mouth. That is just so out there.

[Blundetto]

Great line by Jim Jeffries, better than Shindler's List ha ha.