@whitewolf2226 Actually the number of CAG repeats can expand in meiotic cells. The person wouldn't be at risk themselves, however they could be close to the threshold and pass on the disease to an offspring. Males in particular have a higher chance of being a "carrier".
@tjholland1 What part of the video segment are you referring to? People are born with either the expanded gene or not, so unintentionally people with expanded gene are carriers of HD without knowing it for many years, until they develop symptoms.
@tjholland1 Actually the number of CAG repeats can expand in meiotic cells. The person wouldn't be at risk themselves, however they could be close to the threshold and pass on the disease to an offspring. Males in particular have a higher chance of being a "carrier".
you can't be a carrier, you either have the gene or not. my dad and brother died of it!!! and I know Nancy.
whitewolf2226 7 months ago
@whitewolf2226 Actually the number of CAG repeats can expand in meiotic cells. The person wouldn't be at risk themselves, however they could be close to the threshold and pass on the disease to an offspring. Males in particular have a higher chance of being a "carrier".
sarge525 7 months ago
How can people be carriers? huntingtons is caused by the dominant allele? therefore if they have it they should express it? Sorry, a little confused.
tjholland1 1 year ago
@tjholland1 What part of the video segment are you referring to? People are born with either the expanded gene or not, so unintentionally people with expanded gene are carriers of HD without knowing it for many years, until they develop symptoms.
just1moreperson 1 year ago
@tjholland1 Actually the number of CAG repeats can expand in meiotic cells. The person wouldn't be at risk themselves, however they could be close to the threshold and pass on the disease to an offspring. Males in particular have a higher chance of being a "carrier".
sarge525 7 months ago