DNA mutations frameshift

[koalavale]

illuminante....grazie mille!:D

[Mrsjack43]

thank so much I really get it now

can you do meiosis , mitosis and chromosomes abnormalities .. really need it ,

[7101jy]

Thanks a lot for your time in making these videos, they really help!!! can you please make one on the "regulation of gene expression in both prokaryotes and eukaryotes?" Thank you very much in advance for your help!

[pinkmango9708]

thanks :)

[atmyhouse]

Very helpful, thank you!

[babikorean]

SO HELPFUL THANK YOU SO MUCH! you saved me like 30 minutes of studying time! :)

[mv2slash2]

Thank you very much!! //mv2slash2

[AlexaCaius]

Very helpful video! There's one thing I can't understand, might be a stupid question, but you're changing (adding or deleting) one base (eg. G) then why is the process of point mutation said to be changing one base PAIR when only one base is changed not two? If someone could help me out I'd be grateful :)

[BloodoftheProphet]

awesome nice job

[arteta0425]

found it, very insightful. thankyou

[Throatjab]

if a single base is added or removed in a dna strand, does that mean that the whole strand downstream from the insertion/deletion is misread? in other words, would every triplet in the entire chromosome be misread after the mutation?

[gkpeter]

@Throatjab : No, they won't all be off down the whole chromosome. Each gene has its own start and stop.

[Throatjab]

@gkpeter that's what I thought, but wouldn't the start and stop codons themselves be shifted too? or are there other elements that mark when a gene begins and ends?

[gkpeter]

@Throatjab They aren't codons at that level, just specific sequences that define a gene. TATA box and other sequences.

[Throatjab]

ah, i forgot about the tata and gcgc regions. thanks!

[zicand12336]

@gkpeter there are starts and stop codon triplets, but these are building proteins, so the length and/or use changes, so regardless mutations occur

[gkpeter]

@zicand12336 Correct, mutations occur. Some can have catastrophic consequences, others do not.

[badrowes]

thanks man