Added: 1 year ago
From: pmendez01
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  • ROS are reactive oxygen species not spices. Might confuse people unfamiliar with this term :)

  • Also, the damaged bases are flipped out by DNA glycosylases (it's not pre-flipped).

    Finally, what about all the other factors that bind to XRCC1 (such as DNA glycosylases, Polymerase beta, PARP1/2, Ligase 3, etc)?

  • It is bizarre that almost all BER factors are depicted as DNA sliding clamps while PCNA, which is a DNA sliding clamp, is not.

  • Comment removed

  • Another one of God's magnificent creations.

  • this system didn't evolve, I don't care what my professor says.

  • Very cool indeed

  • cool

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