Neutrophil phagocytosis

[taniavass]

so cute, the guy is working so hard to clean our body :) why would we call him tax-collector or policeman? he is a good guy! or girl ;) anyway, isn't amazing?

[SoulDrainer2106]

where's bacteria's whip

[StrongRomanian]

Osmosis Jones got that sucker good...

[CHEVYedsf]

That's amazing!

[BFOEsteves]

Bacteria = taxpayer

Neutrophil = tax-collector

[harrrMONICA]

Why do I find this cute? HAHA

[bmbbr021]

Isso não é um neutrófilo. Se repararmos bem, é um macrófago, pois não há lóbulos nucleares (característicos do neutrófilo) e há a presença de antígeno na ponta da célula (encontrado em macrófagos)

[rfcjsg]

nooby bacteria

[roodriigoprates]

FODAAAAAAAAAAAAAAAAAAAAAAAAAAA­AAAAAAAAAA !

[Sparroweye]

I found this because I have been researching chemotaxis. Having had cancer and my neutrophils were low, I started researching. I am sure cancer will be cured on the cellular or genetic level. That is if they can buck the big money pharmaceutical companies who control who gets the money. Sick.

[aviairian]

They definitely need to add the jaws theme to this.

[dafniiiii]

Neutrophil is so cute! lol

[0000000NoName0000000]

i have damn serious question

how this white cell can detect and follow bacteria despite it is a SINGLE cell that mean it has no brain or nerve system or muscles ???????

[sshekhr]

@0000000NoName0000000 the cell detects chemicals (called chemokines) coming from the bacteria. The concentration of these chemokines is higher close to the bacteria and as you look further away, the concentration decreases. Since the front of the cell is closer to the bacteria than the rear of the cell, the front sees more of the chemokines than the rear and the cell knows the direction it needs to move to catch the bacteria!

[mkgnl2010]

@0000000NoName0000000 there are unique chemical receptors on both bacteria and macrophage, which allows the macrophage to identify the bacteria and move toward its direction by a process called Chemotaxis,

its like the way how the sperm finds its way to fertilize the egg .

But i wouldn't give the credit to the evolution , instead; I give it to God how created every thing in such a unique way that even most intelligent man on the world can imagine

[0000000NoName0000000]

@mkgnl2010 , thank for your response , totally true blind evolution can't make something like this , the neat design in every aspect in this life dispute evolution bullshit ,

take care

استودعك الله الذي لا تضيع وداعئه

[oggleman]

isn't that wonderful? our bodies workin hard to keep us healthy. kinda makes you feel sentimental don't it?

[saurabhjoy2120]

something is fishy about this video... although i do agree now it has been there for a long long time...my doubts are as follows:

1) is this really a neutrophil or a macrophage or T cell?

2) why is the bacteria running away?....Do we know that bacteria actaully runs away from them and play a "catch me if you can" like thing?

3) The most critical thing is that this "neutrophil" is spending so much energy to catch that bacteria.....but it completely ignores another bacteria (0.05s) so close.

[endlessevilinsanity]

@saurabhjoy2120 ThisYou asked some very important questions. video was shown in my science class and according to our teachers explanations:

1) It was indeed identified as a Neutrphil (they can be hard to recognize without staining) T-cells don't phagocyte and macrophages are found in tissue, not blood. It could however have been a moncyte.

2) The bacteria is not 'running away' it's moving around randomly and the leucocyte is 'chasing' it by chemotaxis.

3) Good question. lol

[bloodyhell50]

hahahaha! that was actually kinda funny watching the bacteria being chased by the neutrophil lol

[keiller1989]

so much you have to read to understand what goes on these 30 seconds

[airrick16]

funny stuff

[rjuto30stm]

INCREDIBLE! AMAZING!

[rejar]

Nice!

[LocoRawrRawr]

Bacteria got PWNED!

[lucyrox78]

That's so cool :D

[ctkurtct]

do you know which journal paper does this come from? thanks.

[RealityrealitySeeker]

the bacteria has formyl-methionine on its proteins which is unique for bacterial cells

thus allows it to be identified

[flashmate99]

how does the cell knows were the enemy is?

[TheSonOfDumb]

@ flashmate99

Chemotaxis.

[angelfairy92]

antibodies bounded to the antigen on the pathogen are a chemical signal which tell the phagocyte where the pathogen is.

[TheSkripter]

i was like "go neutriphil!" the whole vid XD

[scientificallyunstab]

hahaha that made me laugh

[theseamonkeysass]

Brilliant vid

[mattsadventure]

wow so awesome

[atawhai5]

Eat the other one!!!!

[atommo918]

lol the epic chase

[roshanakmofidi]

oh so cool.

my bio prof showed this video last week, everyone clapped when the Neuraphil engulfed that bacteria. ahaha.

[i0nical]

i wanna see the bacteria shrapnel get pooped out

[Tilablack]

very good!

[qazwas2001]

its like a microscopic german sheppard

[MrParky105]

OM NOM NOM NOM!!!

[LaughingViolinist]

i agree

[Jaccxk]

wakka wakka wakka wakka wakkawakka wakka wakka wakka wakkawakka wakka wakka wakka wakkawakka wakka wakka wakka wakkawakka wakka wakka wakka wakkawakka wakka wakka wakka wakkawakka wakka wakka wakka wakkawakka wakka wakka wakka wakkawakka wakka wakka wakka wakkawakka wakka wakka wakka wakkawakka wakka wakka wakka wakkawakka wakka wakka wakka wakkawakka wakka wakka wakka wakkawakka wakka wakka wakka wakka.... wakka.... NOM.

[anonimoculto]

@Jaccxk Pac Man: very good game! Make me remember my childhood...

[chanseng]

EPIC WIN.

[horacido2]

this looks like a sui generis version of Pac-Man

[vinicuspatro]

Incrivel!!!!!!

[Tarkvinius]

wow! it literally hunted that bacteria down.

the microscopic world is such a trip.

[Ludde365]

How does it locate it's victims?

[princesscollection]

Ludde,

it uses a mechanism known as "chemotaxis" with transmembrane proteins that locate substrates AKA integrins.

[jarett24]

Awesome. Something different from just the dumb theory we do everyday.

[freedom6927]

wow, i love this video very much

it's really helpful for me to understand the concepts of biology

[Kat0ixtails07]

OM NOM NOM....gulp

[SeanJohnStriker]

i'm boooooring ! when i look this video -____-'

[markgg1]

wow.... life never ceases to amaze.

And yeah, true it does take lomg lol,,, but it gets there in the end (unless you die)

[shortclayman]

a reinactment of the movie The Blob

[ksaGRL]

Neutrophil can engulf 3-20 bacteria and once they do they die immediatley

[matthoop11]

Actually not "immediately," they are broken down in the lysosomes of the neutrophil, by destructive enzymes called proteases. They are also destroyed by free radicals in the neutrophil.

[rikhurley]

lysozymes...

[DondeEstaGb]

did ya'll know that this video was made in 1956

[kawaiishinichan]

wow it really does chase the bacteria.

[hiespike]

awesome! thanks

[BlackRainbow667]

No wonder it takes days for a cold to pass off, if THIS is time-lapse. Thanks anyway for being there at all :)

[jmhthe3rd]

pwned!

[buddhastalin]

pac man

[illegalusername]

Somebody embed Yakety Sax

[Vierotchka]

Bacteria is the plural of bacterium.

[icdapoakr]

On behalf of the whole human species: Thank you, immune system

[masterPee101]

lol. you're funny.

[YouDummy]

phags...

[Turandot29]

So *that's* where the idea for Pac-man came from! ;)

[ertreri]

WOWO

[pflostre]

I wonder if this is real time.

[maggitrymbill]

RTFD: "Video is speed up"

[felixkunze]

I'm gonna be thinking of this next time I am ill 'go little blob, eat those bacteria'.

Simply stunning.

[btnheazy03]

the amazing human body at work

[MustardMunkey]

Uh, you missed one there, friend.

[odantoro]

Beware the Blob!

[JMCCABE83]

That is AMAZING!

[monkeyman1140]

Run Forrest! Run!

[lfessi]

fantastic

[wwwnikdangelocom]

That is one very cool video

[caldog2007]

that little prokaryotic just couldnt run fast enough

[firstjedi]

whata well is that??ªªª!!! omg

[joevacane]

bible says a lot of stuff. it's got a big mouth.

[Kyzersawsay]

Especially alot of bullshit LOL

[fadilto]

I do not think that this is a neutrophil, instead it appears to be a lymphocyte (T cell) because neutrophils have multi lobed nucleus, while T cell has big nucleus with vary small cytoplasm. What do you think?

[Sicarioi]

cannot be a lymphocyte, lymphocyte has same size as blood cells and this is bigger

[Fullblaster]

It may look like a macrophage in my opinion.

[happynurse63]

That is AMAZING!

[sweetycheeks]

the bacterium actually looks scared lol

[mudjh]

genial microscopio? muestra? como lo hacen?

[1researcherdotcom]

Nice video.

[Enantiomero24]

Jaja, asombroso.

[thealexthing]

how much was this sped up by?

[stephizzal]

i don't know why this should be funny, but it is. Nom.

[magicalangel0]

isn't supposed to be a sound? I saw this clip at another site with a sound..

[danAlj]

are you stupid??? what do you wanna hear? a neutrophil talking to you??? dumbass!

[magicalangel0]

the website where this was hitched from had a sound DUMBASS. that's not what I meant at all. And you thinking that makes YOU an idiot. Way to insult someone on the internet.

[iggy4323]

Hahah!

[simonobli]

This clip can be found on the "Janeway's Immunobiology" CD. The voiceover basically descibes how the neutrophil moves towards the bacteria via chemotaxis, while the bacteria are just moving randomly.

[bevamartin]

Interesting to see leukocytes eat a microbe under the microscope and display a form of cellular immunity indicative of mammalian immunity.

[orelko]

I don't think that macrophage gets the joke :D

[drivinshark]

Yo le agregué música a ese video chéquenlo en mi nombre jeje saludos, genial el video...

[gregvs3]

Humans - 1

Prokaryotes - 0

[SomaliJane]

OM NOM NOM

[AyemNFS]

All this video needs is the Benny Hill theme going in the background and it'll be amazing!

[droserabinata]

Cool!

[c3030328]

awesome thanx for sharing...any idea what kind of bacterium that was?

[piastresx]

it's a Staphylococcus aureus

[manuelschutze]

actually you can't say this for sure... especially because Staphylococcus bacteria are usually found in grape-like groups (that's why they're called Staphylococcus). as the bacterium is seen as a diplococcus, maybe it's a Streptococcus pneumoniae or Neisseria gonorrhoeae...

[VxUxBx]

bom, bom!

[igorofhell]

massa

[yupanqui13]

que alucinante, absolutamente implacable

[mmt123]

poor little bacterium