@bilbo317 Look at the processed foods you are eating, and STOP and READ!
The chips, the cereal, and just about anything PROCESSED is made from high fructose corn syrup, our bodies don't know how to break down this chemical nightmare! Look around you, type 2 is out of control.
Keep eating your "Little Debbie's" etc, see where it gets you...
Yes! have something sweet once in awhile, make it yourself, relearn the word "treat"
@bilbo317 development of insulin resistance is very complex... basically it is associated with obesity. there's a theory called randle's cycle. It states that fatty acid competes with glucose to be used as the fuel in the skeletal muscle. obesity increases lipolysis and thus free fatty acid level. This spares the glucose from being used, the high glucose level continues to stimulate pancreas to release insulin to stimulate the uptake of glucose. this will downregulate insulin receptors
@thoreric86 oh, that's a different way I have heard it being explained. All I've really heard was... because there is so much glucose in the blood (obesity), but the receptors can't handle the amount and down grade because of the stress on the body. ... but I thought that the body always wants to use glucose first because it's easier to process... and not compete with fatty acids, but the body has no choice to use fatty acids once the receptors down grade. Are there different theories?
@bilbo317 The competition between glucose and FFA in muscle cells (randle's cycle) is proven to be one of the reason of insulin resistance. Note that it is happening in the muscles. you have to differentiate between insulin-sensitive and insensitive tissues. those that are insensitive (e.g. brain) will still use glucose as primary fuel. the other insulin-sensitive tissues is adipose (fat). adipocytes appear to be enlarge (hypertrophy) in obese ppl, it is proven that hypertrophic
@bilbo317 adipocyte show distinct gene expression. this results in a change in the insulin signalling system and hence insulin resistance is seen. In the one that u heard, my very first question is why is there so much glucose in the blood? it is because its disposal mechanism failed to function. why cant function? because the insulin is not working properly. why not properly? becoz of insulin resistance.
@thoreric86 The theory you present assumes all type 2 diabetics are obese. Thin people get type 2 diabetes too. And there are obese people without diabetes....
@DrSpooglemon Indeed. If i'm not mistaken, obese-type2 is called type 2b, non-obese type2 is called type 2a. For the non-obese case, it's due to beta cells dysfunction (deposition of amyloid peptide), which is also seen in obese type in the later stage.
As to obese without diabetes, I would say it is a matter of time. the cause of death in the obese case mostly reported to be due to CVD. But, if they survive long enough, they will definitely encounter diabetes. ^^
@bilbo317 You got that a bit muddled. If insulin levels are high the insulin receptors will downregulate. This is true of any hormone. Heroin stimulates the mu-opioid receptors and heroin addiction is caused by the downregulation of these receptors.
Once the receptors downregulate more is needed and so insulin levels keep increasing in a viscous cirlce of receptor downregulation until the body cannot sufficiently respond to any amount of insulin. Then you have diabetes...
I've recently found out I have some type of diabetes I'm thinking it's type 2 but I'm not sure. I pass out and get very light headed, my bowls get loose and I get very nautious. Everything turn into a blur and just confusion. My uncle came down today to check my sugar levels. And they were extremely low 45.
Please if you can get a one touch basic. it uses photometric testing and is the most accurate. They are no longer available but you can get them on e-bay. I was taken by ambulance because I had passed out from low blood sugar 32 but the ultra meter said 300 . I wear a medical alter bracelet to only test with serum blood no ultra meters!
If you have blood disorders ALL ultra meters will read false high!This is as per makers of one touch .
This has been flagged as spam show
diabetescaution.blogspot.com ............ very nice diabetes health tips for you
sophiathomas210 2 months ago
great happy
GinjaNinjaHD 4 months ago
This is good, but it doesn't explain at all how Type 2 actually develops--WHY does the body become resistant to insulin?
bilbo317 4 months ago
@bilbo317 Look at the processed foods you are eating, and STOP and READ!
The chips, the cereal, and just about anything PROCESSED is made from high fructose corn syrup, our bodies don't know how to break down this chemical nightmare! Look around you, type 2 is out of control.
Keep eating your "Little Debbie's" etc, see where it gets you...
Yes! have something sweet once in awhile, make it yourself, relearn the word "treat"
Not everyday,
porcelaincougar 3 months ago
@porcelaincougar thx :) but I meant more on a physiological level... I was trying to look for visuals to help out with my test
bilbo317 2 months ago
@bilbo317 development of insulin resistance is very complex... basically it is associated with obesity. there's a theory called randle's cycle. It states that fatty acid competes with glucose to be used as the fuel in the skeletal muscle. obesity increases lipolysis and thus free fatty acid level. This spares the glucose from being used, the high glucose level continues to stimulate pancreas to release insulin to stimulate the uptake of glucose. this will downregulate insulin receptors
thoreric86 2 months ago
@thoreric86 oh, that's a different way I have heard it being explained. All I've really heard was... because there is so much glucose in the blood (obesity), but the receptors can't handle the amount and down grade because of the stress on the body. ... but I thought that the body always wants to use glucose first because it's easier to process... and not compete with fatty acids, but the body has no choice to use fatty acids once the receptors down grade. Are there different theories?
bilbo317 2 months ago
@bilbo317 The competition between glucose and FFA in muscle cells (randle's cycle) is proven to be one of the reason of insulin resistance. Note that it is happening in the muscles. you have to differentiate between insulin-sensitive and insensitive tissues. those that are insensitive (e.g. brain) will still use glucose as primary fuel. the other insulin-sensitive tissues is adipose (fat). adipocytes appear to be enlarge (hypertrophy) in obese ppl, it is proven that hypertrophic
thoreric86 2 months ago
@bilbo317 adipocyte show distinct gene expression. this results in a change in the insulin signalling system and hence insulin resistance is seen. In the one that u heard, my very first question is why is there so much glucose in the blood? it is because its disposal mechanism failed to function. why cant function? because the insulin is not working properly. why not properly? becoz of insulin resistance.
thoreric86 2 months ago
Comment removed
DrSpooglemon 2 months ago
This has been flagged as spam show
@thoreric86 The theory you present assumes all type 2 diabetics are obese. Thin people get type 2 diabetes too. And there are obese people without diabetes....
DrSpooglemon 2 months ago
@DrSpooglemon Indeed. If i'm not mistaken, obese-type2 is called type 2b, non-obese type2 is called type 2a. For the non-obese case, it's due to beta cells dysfunction (deposition of amyloid peptide), which is also seen in obese type in the later stage.
As to obese without diabetes, I would say it is a matter of time. the cause of death in the obese case mostly reported to be due to CVD. But, if they survive long enough, they will definitely encounter diabetes. ^^
thoreric86 2 months ago
@bilbo317 You got that a bit muddled. If insulin levels are high the insulin receptors will downregulate. This is true of any hormone. Heroin stimulates the mu-opioid receptors and heroin addiction is caused by the downregulation of these receptors.
Once the receptors downregulate more is needed and so insulin levels keep increasing in a viscous cirlce of receptor downregulation until the body cannot sufficiently respond to any amount of insulin. Then you have diabetes...
DrSpooglemon 2 months ago
Green tea may help diabetes a lot!
taichigreentea 5 months ago
I've recently found out I have some type of diabetes I'm thinking it's type 2 but I'm not sure. I pass out and get very light headed, my bowls get loose and I get very nautious. Everything turn into a blur and just confusion. My uncle came down today to check my sugar levels. And they were extremely low 45.
ghostly573 6 months ago
@ghostly573 that's hypoglycemia... diabetes is hyperglycemia :P
thoreric86 2 months ago
Very Helpfull Animation. Tx very much, Im using this video for my Blog too as well. If it is ok .....
kesehatanPLUS 10 months ago
This has been flagged as spam show
Please if you can get a one touch basic. it uses photometric testing and is the most accurate. They are no longer available but you can get them on e-bay. I was taken by ambulance because I had passed out from low blood sugar 32 but the ultra meter said 300 . I wear a medical alter bracelet to only test with serum blood no ultra meters!
If you have blood disorders ALL ultra meters will read false high!This is as per makers of one touch .
Write to congress to bring back photometric meter
7824jq 11 months ago
Fantastic Video Channels. It's important that I saw your Video channel as I want to learn more. More power.
dmguru4u 1 year ago
ow know
Rexmanghay 2 years ago
part 2 diabetis
Rexmanghay 2 years ago
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Rexmanghay 2 years ago