Added: 1 year ago
From: bryantsiao
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  • Topoisomerase?????

  • What exactly does 'the 2 parent strands are anti-parallel mean'? This sentence is also in my cursus but can't figure out what it means. thanks!

  • Comment removed

  • @yesinmsadek it means they have opposite directions but are still placed parallel to one an other: 3'-5' and 5'-3' are antiparallel

  • very very nice. :) it doesn't show topoisomerase activity, but other than that, very good and clear presentation! favorited.

  • Fine job.

  • Have some questions to you:

    1. I always thought that the replication fork untwines the DNA helix from the begining of the cain, meaning from the first free nucleotides in the begining of the cain. Inversly you have depicted it to untwine the DNA in a kind of bubble like in the case of the RNA transcription. What is the right claim?

    You've depicted the leading strand a been oddly. .2

    I mean I hearing for the first time that RNA primers are attached to the leading strand. Is it so?

  • @kushalaimashkha

    Because DNA polimerase doesn't need any primers since he builds from 5' to 3' which coincides with the structure of the leading strand(3'>5') but does not coincide with the lagging one, in which the need of primers occur.

    Thanks man

  • muy bueno. (is a very good video) Thanks!

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