Sort by time | Sort by thread (beta)

Link to this comment:

Share to:

All Comments (303)

Sign In or Sign Up now to post a comment!
  • That run with only Items from the devil was (i hope that for you) your WORST run ever. You were only INCREDIBLY lucky! You made every single mistake possible and if you really had a worse run than that it would mean you would have died on the tutorial room without even enemies.

  • Picky, Picky, Run: Have to use the D-6 on every item, good or bad.

  • C'mon man, if ever it's acceptable to pick up brimstone, it's a run where only dark/satanic items are allowed.

  • Should have totally taken the shears. Suicide is a sin, mother fu-!

  • You could try this: A run there you are only allowed to get each second item.

  • Actually it's "neither... nor," but you said "neither... or."

  • You were killed in the DEPTHS?! Are you kidding me!? You are better than this Northernlion!

  • Health items only

  • Everything in binding of issac is evil :X

  • you should make a challange run with no health upgrades or spirit harts

  • you should have pick up the brimstone :/

  • here's a challenge: you can't go to the shop and you must go to the arcade at any possible chance.

  • After 5:55 you could instead pick up the Dr Fetus Remote to blow up the wall with the secret room and THEN reroll it (its an evil item and you can repick up the Dice after being done with it)

    I suggest this little challenge: When a Devil Room appears, always chose the item on the left regardless of what it is and as long it doesn't END the game (you CAN die by using a Cat item) That also means that you can keep going with no hearth containers

  • my challenge is: you can only open 4 item rooms and pick up anything in them or from a boss fight and secret room but deals with the devil items

  • something something dark side

  • @lolorainga Something something something DARKSIDE. Something something something COMPLETE.

  • 0:00 He was thinking about Brimstone :3

  • Only take Spirit hearts no HP pickups

  • Original: Can only pick up classic items. No items you have unlocked or items from the Halloween update.

    *Can allow the d6 for easier game-play*

  • Tough Economy- You must go out of your way to collect Coins. That means you have touse bombs to get one coin and keys on chests. You cant spend any of it ether,

  • Can only use items from bosses

  • Life isn't free. Don't pick up any items that you can find for free. (no items in the item room etc.) You can only pickup items that you pay for. (the shop, slot machine, skull guy, bloodbank judgement guy.) (You can also increase the difficulty by including bombs, spirit hearths and hearths as free items unless you pay for them), though you can always pick up keys so you can go to the shop and money.

  • Or better yet a "mix it up" run, for every floor u pick a different set of run rules

  • I think your inner English-teacher was coming through on this video Lion XD

  • "ima a firing mah knife" run

    Only able to pick up items that change the way u attack

  • Harder Better Faster Stronger:

    Passive upgrades for stats only. Nothing that would change how you attack. (No Technology, Brimstone, Mom's knife, Spoon Bender, Ouija Board, Piercing Shots, Multishot, Parasite, etc.)

  • Blue Baby run: just beat Satan again as Blue Baby. A tough challenge in itself, no restrictions.

    "I think I have a problem" run: never use the shop, every skull guy, judgement, and slot machine encountered must be used until it breaks or you're out of cash.

  • MOAR BINDING I WILL DIE WITHOUT Ps :LOVE YOUR COMMENTARIES

    Psps ALL CAPS RAAAAAAAAAAAAAAAAAAAAAAAAAAAAA­AAAAAAAGE

  • how about you only get one upgrade per a floor or space bar item a floor

  • Hmm...

    Sniper: Can only pick up items that increases range and damage. Technology and Brimstone are not allowed, but Chocolate Milk, Ouija Board, and HP Ups okay. Also, any Tears Down pills must be taken.

    Gatling Glory: Tears/Damage ups only, Ouija Board and health boosters allowed, Range Down pills must be taken if encountered.

    MORE POWER!!!!: Should be obvious. HP Ups, Mom's Knife, and Brimstone allowed.

    Express Checkout: Can only pick up 5 items or less over the course of the playthrough.

  • Handicap run: You can only shoot left or right. Not up, nor down.

  • Honestly, considering this to be a dark side run, Brimstone would have been ok to use.

    You shouldn't overuse it of course but this kind of run is predestined for this kind of item.

  • How about a Coin Toss run?

    At the beginning of every floor you flip a coin and if it's heads you have to pick up every item on the floor (good or bad, akin to a ADHD run), and if it's tails you can't pick up any items, (bombs, keys and money are exempt, you can always pick them up, otherwise it would break the run!)

  • binding of isaac multiplayer

  • Challenge run: Im a baby again

    You cant use any spacebar items or keys or coins or bombs when in the womb.

  • Anti no item challenge update and namechange

    Challenge run: Oh the keys

    You can not pick up bombs or money in this run the rest is fine...

    Challenge run: The Hyper active Child

    You must use your spacebar item as soo as its charged. Same for tarot cards and pills as soon as you have them you must use them

  • Who else thinks that taking brimstone would have actually made this video more INTERESTING?

  • Congrats on Isaac video 100! We're still loving them.

  • Congrats for your 100th video of isaac :)

  • well that was a horrible 100 video...

  • Amnesia would be a fantastic let's look at. Maybe even a let's play

  • Space_is_broken challenge

    No spacebar items

    Dun DUn DUN DA DUMM! Challenge

    Open every chest you can.

    Im a Barbie girl. In a deadly world. Challenge

    Go a Magie or Eve and only grab items a girl would use.

  • How 'bout a nutral run. Only pick up items without clear alignment.

  • Oh.. youre doing the dark side one? I thought you were doing the light side one.. cause I didn't pay attention in the beginning? =\ ... I was like "don't pick up the horns, man!" Damn..

  • No bomb run.

    No The Tower, no Fetus in a Jar, no Anarchist's Cookbook, no Bob's Rotten Head, and if you get an Explosive Diarrhea pill you can't benefit from it.

    Any other means of getting to the secret room or destroying rocks is fine, be it The Nail to crush rocks or X-Ray Glasses to get into the secret room.

  • Challenge run: the shape shifter

    Only have the right to pick up apearance changing items

  • Challenge run: The passive person.

    You can only use passives in this run.

    Challenge run: The Action hero

    You can only use spacebar items on this run.

    Challenge run: The anti-no items run you can only pick up actives and passives but no bombs keys or money.

    Challenge run: our cherished child

    You must bypass mom fights.

    Challenge run: the berzerk

    You xan only pick up helth ups and damage increases

    These are just from the top of my head

  • @MrBerti11 The anti no items is flawed.

    How can he pick up items without bombs,keys or money?

    The action hero challenge run is also very difficult without passives,its almost impossible.

  • PASSIVE RUN: no space bar items and you must play as JUDAS just so you can have the book of belial

  • What about an Impartial Median run: For every evil item you pick up, you cannot pick up another evil item till you pick up a good item and vice versa. Neutral items are allowed at any time.

  • hundo eps deep?

    craze.

    A+!

  • I like the idea of covering your HUD with stocky notes so you can't see what you have...

    :3

  • If this is an evil run. WHY WOULD YOU GIVE TO JUDGEMENT?

  • QWOP: Change movement keys (if possible) from WASD to QWOP

    Sonic's the name, speed's my game!: Collect every possible speed upgrade

    NOPE! Chuck Testa: Collect every animal related item (while making a joke each time)

    My Little Pony: Use MLU as many times as you possibly can in one run

    X all the Y: Collect ALL the things!

    THIS! IS! SPARTA!!!: Max. Damage, Min Health, no familiars to help you

  • Challenge Run - You Have What! Do a run where you can only pick up Items that make you diseased ridden Example- Bob's rotten head, the virus, or anything that would make you malformed.

  • Challenge run: "Meet the...": Whenever you encounter an enemy for the first time, you must engage it in a short conversation/interview in which we learn something new about that enemy. You speak for both yourself, and the enemy. Ad libed, of course.

  • Congrats on 100!!! Side note: I am loving that YouTube is on XboxLive now! These vids are awesome on my hdtv and im rewatching alot of my faves.

  • addict run: Continued

    must buy at least one item from any possible trades with the devil

    if you get a taro card you can use it as long as it can feed your addiction (wheel o fortune, blood bank, judgment)

    you must pick up all needle items, even if it triggers a mob trap or is useless to you

  • addict run:

    gamble all of your money, no shop if you find an arcade (search entire floor first)

    if you have no spare hearts lying around to spend at the blood bank, spirit hearts will do >:)

    always eat pills (even if it kills you)

    if you find moms pill bottle you may visit the store solely to buy the battery or 9 volt

    must play as Issac or Cain

    if you play as Issac, you must re-roll an item before you can take it

    if you find the steam sale, you may visit the store

  • Dyslexic Run: Rebind your controls so that movement is backwards. eg "A" goes right, "D" goes left, "S" goes up, "W" goes down.

  • @iiscotty91ii That's not that hard to do, easy to get a hang of. Perfect for me!

  • Iron Man Run: Can only pick up items made of metal. (plus keys,bombs, pills, etc.) Could argue certain hp ups have iron in them (hint hint)

  • i like rebelwinterwolf's idea for the christmas special: only green or red items (including pills)

  • 'We are the champions... not' run:

    Don't pick up items dropped by champion enemies... or only pick up those, but that could make the run impossible.

    Stats denied run:

    Choose a stat or two. Never pick up anything that boosts those stasts (hybrid items included, maybe familiars included).

  • @ReadInPeaceSG

    Forgot, stats should be:

    Damage, hp, speed, firerate, spirit hearts, range, flight, tear effects, can't think of more. Or maybe you could choose two stats and only pick up stuff which give those two as my initial idea might prove to be too easy.

    Another run, Soulless:

    Never pick up any spirit hearts, not even items that give them. Should be fun with Blue Baby, lol.

  • No health upgrade run. Spirit hearts are fine.

  • Hey he sorta took my idea for a demonic run

  • expecting something more for 100th vid

  • No change run:only pick up items that do not change your appearence, such as brother bobby, little chad, etc. and protecters, such as pretty fly, guardain angel, etc. Also no pills since they can change your color or face, your character has to look the same at the end as they did in the begining.

  • Shitty item run XD

  • 100 episodes from a piece of shit game ,congratulations northernlion.

  • the one liner run- once per room u must say at least 1 one liner or when picking up an item.

    (rooms with no enemies not required)

    you can do this by itself or combine this with another challenge run

  • NO BOMBS OR KEYS

  • ! Christmas Special Run

    Only pick up red or green items; 1up, <3, virus, sister Maggy,sad onion, roid rage, common cold, Bob's rotten head, etc.

    That, or do a "good" run; bible, rosary, Christian things. But you have to sing us a Christmas song :3

  • This is the second time he's been with a half a heart for more than 3 rooms. Why does he not pick up whore of babyon?

  • :/ I wouldn't have yelled at you for Brimstone. All we wanted earlier was a break from it, just so long as you use it in moderation you should be fine.

  • Challenge Run - Oh god how much health and keys and bombs and cash do I have and where am I and what spacebar item do I have oh god

    Cover your HUD with sticky notes.

  • Only shoot horizontally.

  • 13:27 "I'm not passing judgement"

    13:37 Passes right by Judgement

    xD

  • "Hopefully one of these guys drops a key, otherwise I'm kind of hand-cuffed here" - 9:05 Lol nice unintentional pun xD

  • Heehee, when he picked up the pentagram it looked like his horns grew

  • <3 for not picking brimstone again

  • Cartell run, only use pills and mushrooms, (mons bottle of pills and phd are allowed)

  • Bombs Away: no using bombs

  • Challenge run: (name: the poop of doom!) play as blue baby and you have to keep the poop, no other spacebar item but you can get collectible items.

  • only items bought in store?

  • challenge run: every opportunity you have to make a deal with the devil you have to take it even if it means death except on the basement.

  • NL I'm not passing jugment 10 seconds later hi judgment

  • Roach Motel

    Can only use gross/dirty items

  • No costume use any character cant change apperal

  • drawkcab gnikaeps: speak backwards for 5 minutes

  • Went back to watch the first video of this series in honor of the 100th video of it.

    Holy fuck have you come a long way. xD

  • Northernlion: If i succeed on this run, that'll be three challenge runs in a row that i actually succeeded.........

    Me: Looks at time, probably doesn't happen :P

  • Shot Challenge:Drink a shot of liquor everytime you take damage of one heart.

    everything is allowed

    no restictions

    have fun :P

  • @MWGFADDER I would love to see that hah

  • SHIT: use dead baby cant change the poop spacebar item

  • Under a Rock Run: No references to popular culture whatsoever.

  • 22:35

    "You can really see the way that kind of looks like a vagina when they show you the picture there."

    That..... that's what she said?

  • I dont really care if ryan wants to take brimstone and i personally like brimstone

  • Challenge run: One of a kind: You can only go to one item room, one shop, one devil room and you can only get one boss item, arcade item, mob trap room item and secret room item. Item's like the rock or ones from gold chests are still allowed.

    Non rechargeable: You may only use each space bar item once, then you can't use it again.

    3 strikes: Play as blue baby. You are not allowed to pick up any spirit hearts or hp ups. Getting a hp up pill for the first time is ok, but after that, no.

  • As Eve, beat the game entirely in the Whore of Babylon state, which means you retain half a red heart the entire game, but you can still rack up on soul hearts.

  • you should have done a speciel tribute video for your for 100th episode. I even wrote this day in my calender lol "Isaac Day"

  • Moon-Speak Run: Play the game only speaking Korean.

  • @AGrayPhantom THIS!

  • But Brimstone would've made you look so badass!

  • Ive literally missed 10+ videos from you because Youtube wont show me them. AAAAAAAARGHHHH

  • The Clown: Pick up items that make you look silly, or have a make you laugh at the idea of the items absurdity IE moms pad...

  • wow, the one hundredth video, it's so amazing, at least to me. Because I only have one decent video, that is nowhere near as cool as any one of these binding of Isaac videos, and I would think that the first one hundredth video would be an accomplishment, but one hundred video's of the same game AND it's not boring yet? now that's an accomplishment.

  • only hp ups

  • drunk run

    nuff said

  • Get to mother's heart while not getting hit more than 25 times.

  • Can you possibly link me to your devil room items only video?

  • @fuzzum111 isnt that one the last video he did, 99

  • @raffsterclub Oh do you mean like only devilish items, I dont know what video that one is.

  • Ok I got one for you.... tank run! you are only allowed to get items that let you (tank) more damage, (bombs, keys and pills exempt, tero cards aren't) such as, hp up, poop helmet, all stats up, pretty fly, or things like the relic or yum heart that heal you, also devil deals weaken you so they are off limits. Lastly a SINGLE cube of meat is exceptible.

  • LMAO "in the eyes of rick perry" 14:56

  • Challenge Run: Transvestite> Only use items who are "meant" for the opposite gender. (No ??? >:[ )

  • the seven deadly sins drops:

    sloth - bobs rotten head

    greed - the steam sale

    glutny - heart

    envy - shoop tha whoop (rare)

    wrath - mr.boom

    lust - the virus

    pride - the anarchist cookbook

  • @MrTeamTea Gluttony can drop lard, but's its super rare.

  • @MrTeamTea Glutny? It's Gluttony. Shoop tha whoop? It's Shoop Da Whoop.

  • @4evaNerdz Stop being so glutnus with your letters, you big glutn.

  • @SamildanachEmrys I am sorry, I only speak English.

  • @4evaNerdz I know. Humour is humorous.

  • Comment removed

  • It's not the overpowerdness that makes us not like it, it is the slow recharge we hate.

  • LOL YOU MOVED THE ANNOTATION CUZ THE GUY TOLD YOU TOO!

  • Shit Run Challenge: Use Blue Baby and take a shit in every room

  • Taxonomologist: Call every enemy in the game correctly.

    :D

  • Brimstone would have helped so much.

  • Do This One If Not Done: Elemental Run: Only pick up items that are made or Fire, Water, Earth, Air, or any mineral. Ex. Technology, O.K because of the Metal. Yum Heart, No because it was from a living thing and not from the ground, etc.

  • is this your last binding of Isaac lets play?

  • favourited for 100 episode

  • ADHD evil and good runs so if you so something evil you must pick it up

  • Face the Odds - Only pick up items on odd numbered levels. This includes not picking up boss rewards on all even numbered levels, no deals with the devil on even levels. Only exception are hearts, bombs and keys.

  • ghallenge run:only use boss ietims!!

  • CHAD=GURDY+CHUB

  • Grats, 100 episodes, I've watched them all!

  • @NorthernLion Challenge Run: Don't say you're doing a challenge run at the beginning of the video, then purposely say the wrong name for absolutely every item you see, and see if anyone catches on.

  • @sirfragalot92 Dude! That would be awesome! I'm serious. I would pay Northenlion money to have him do that run. :)

  • You need to do an extreme hardcore mode.  Blue baby with no item pickups.

  • there is a new achievement called a gift from krampus

  • northern lion, i think you underestimated the parasite when you had it. i had good damage and range increased, and i killed gurdy with the parasite in about 30 seconds because i was hitting him three times. and on most enemies if you hit them to the left or right you essentially get a double shot. it also fills the screen with bullets.

  • Congrats to you on 100 episodes. Cheers.

  • challnege run: use light-side items (you can only get dark items from the devil)

  • Would suggest a kill all horsemen challange run but course it's randomly generated whetever they show up or not XD

  • Try "good cop bad cop" put angelic items and demonic items alternativng with each item

  • Pride: Anarchist cookbook

    Sloth: Bob's head

    Gluttony: <3

    Envy: Shoop da woop

    Greed: Steam Sale

    Lust: Poison Touch

    Wrath: Mr. Mega or Mr. Boom

  • Challenge run: you can't take any hearts including spirit hearts.

  • Shears-> Cuts your head-> Brutal-> EVIL

  • FUAAAAAAAPAA... yeah I know your tricks Ryan, i'm watching you o_0

  • I wanna see more time on this series

  • Amnesia Run: Once u leave a room once u cannot pick anything up in that room if you go back in it

  • Congrats on 100 episodes. Here's to a few more. :)

  • Like a Boss:

    Each floor, as soon as you find the boss you must fight it and go down a floor.

    Items taken can only be from boss/miniboss rooms and devil rooms (i.e. no item or shop room items)

  • Mother fucker...youtube didn't show the past 10 episodes.

  • Comment removed

  • I appreciate you not taking brimstone in this video

  • Challenge Run: only use items bosses or mini bosses drop

  • andy dick run: take nothing that increases your damage or makes you stronger(brimstone,technologie ect. but tears ups are allowed)

  • Gratulation for 100 parts of Binding of Issac :)

    Cheers

  • :D

  • Bipolar Run: You can pick up any item that you like, but the next item you get has to be completely thematically different. So if you pick up a technology item, your next item must be a religious item. If you pick up an HP up, your next item must be a damage up.

  • Pooptacular: Choose Bluebaby and keep the poop for the whole game (so no other spacebar items, everything else is OK)

    Pray for a nickel!

  • CHALLENGE:

    you're ONLY allowed to use brimstone. no upgrades of any sort, no spacebar item (other than D6), no companion shooters (brother bobby etc.) however, you are allowed to use pills and terro cards

  • Fate is a Bitch Run: Must have either the Rosary or Angel to beat the game. It is suggested you use Isaac, because he has the D6. You cannot use Tarot Cards or Ouiga Bourd, as they are parts of fortune telling.

  • The Sinetra2 Run - Well since I keep trying to tell you what u do wrong in your videos, I think it's time to see how you handle mistakes you do on purpose!

    You see a blue rock - You miss it. Oops!

    You forget about all secret rooms

    On the 3rd and 4th floor - You forget to goto the item room! Silly u!

    If you happen to find some item that is behind a rock or a keylock and you miss a key or a bomb to get to it. It's gone! Even if later u find a bomb or a key. You 'forget' to go back to it :D

  • @Sinetra2

    sounds like northernlion might complete this run on a future lets play completely by accident.

  • @zeejustin6 Haha to be honest I'm pretty sure he already did that in 1 LP without us noticing :D

    Would be funnier to see him do it intentionally tho :D