Carcinoid Syndrome: Most important Points

[TheGudov]

Thanks very much Dr.paul...its really very helpful information...@4:46 you said somatostatin receptor scintigraphy while at @7:13 serotonin receptor scintigraphy???

are both available OR its only the somatostatin that is in use now?thanks in advance.

[karlacazadora27]

"ATYPICAL Carcinoid Syndrome is rare and is associated with foregut carcinoid tumors. It is characterized by extended episodes of flushing, headache, shortness of breath, and in rare cases, lacrimation (tears)...."

INCORRECT" ATYPICAL" NET TUMORS REFERS TO THE GROWTH OR MITOSIS OF THE TUMOR. ITS DEFINED A TYPICAL OR SLOW GROWING TUMOR, OR ATYPICAL, FAST GROWING ASSC, W KI INDEX OF >20% OR MORE.

WHAT THE AUTHOR MEANS IS ASYMPTOMATIC= TUMORS WO CARCINOID SYNDROME, OR SYMPTOMATIC=SYNDROME.

[Allibaby78]

Individuals with Carcinoid Syndrome can also experience Carcinoid Crisis which can occur spontaneously or be stress induced. A Carcinoid Crisis can be a life-threatening event that requires careful monitoring. Symptoms of a Carcinoid Crisis may include severe hypotension or hypertension, irregular and/or rapid heartbeat, wheezing, prolonged flushing, severe dyspnea (shortness of breath), and peripheral cyanosis (lack of oxygenated blood).

[Allibaby78]

ATYPICAL Carcinoid Syndrome is rare and is associated with foregut carcinoid tumors. It is characterized by extended episodes of flushing, headache, shortness of breath, and in rare cases, lacrimation (tears). The flushing can be deep purple and last for hours. It may be followed by increased blood flow to the limbs (arms and legs) and to the trunk (chest, stomach and back). This flush is not brought on by food.

[Allibaby78]

Flushing and diarrhea are the two main symptoms that are associated with Carcinoid Syndrome. Diarrhea can be mild to severe which may lead to weight loss and life style changes. The flushing may be light pink to a deep red and occurs in the face and in the nipple-line. It may be triggered by stress, alcohol, exercise and certain types of foods.

[Allibaby78]

ypical Carcinoid Syndrome is the most common form of Carcinoid Syndrome and is most often caused by midgut carcinoids that have metastasized to the liver. Excess serotonin is the hormone most frequently related to Carcinoid Syndrome. The syndrome is characterized by brief episodes of flushing, diarrhea, cough, wheezing, shortness of breath, heart disease, and in rare cases, pellagra

[Allibaby78]

Mnemonic for main symptoms of carcinoid syndrome= Four WHeel Drive i.e Flushing, Wheezing(with shortness of breath and cough), Heart disease(especially right-sided), and Diarhoea!

[Allibaby78]

Carcinoid tumors are usually indolent (slow-growing) by nature and develop over the course of many years. However, aggressive, fast-growing forms of carcinoid cancer also exist.

[Allibaby78]

The majority of neuroendocrine tumors can be divided into two classes: carcinoid and pancreatic neuroendocrine tumors. Carcinoid commonly refers to neuroendocrine tumors that originate in the gastrointestinal (GI) tract, lungs, appendix and thymus, although they can also occur in the lymph nodes, brain, bone, gonads (ovaries and testes) and skin.

[VASHOTAC]

great explanation!! :)