MS Patient After Stem Cell Therapy

[whitecaucasian]

please somebody tell me:

my son has juvenile dermatomyositis and only stem sell transplantation will help him anyhow or he needs chemotherapy in advance ???

we would like to cure him without chemotherapy.

what do you think this method of treatment will help us ??????

thank you in advance.

[gekiryudojo]

you look a picture of health after the stem cell treatment lol

[pvdxtc]

Hi, I am 28 and have been ill with chronic fatigue syndrome. I am weighing my options for stem cell treatment and am considering either going to your clinic in panama or the one in India run by Dr. Geeta Shroff. Can you please tell me in your opinion the diff. in treatment with cord stem cell compared to embryonic cells.

Thanks!!

-Alex

[cellmedicine]

@pvdxtc Hi Alex, the difference is a very important one....embyroinc stem cells usually cause a type of tumor called teratoma...only two FDA trials have been approved and these were approved after the companies Geron and Advanced Cell Technologies has spent millions of dollars trying to ensure that no undifferentiated stem cell contamination was in the therapeutic product....fetal stem cells are actually documented to have caused a tumor in a patient treated...

[pvdxtc]

@cellmedicine Thanks for the quick reply! From what I have read, Dr. Shroff has treated over 800 patients so far without complications, however, as they say.....past performance is not indicative of future results. From your experience can you comment on the results of cord blood cells compared to hEST....from my logic im looking at it in the way that since hEST are "totipotent" they posses a higher level of therapeutic benefit ....i would love to hear your thoughts on this.

Thank!

[cellmedicine]

@pvdxtc excellent question...you are absolutely right in that ES cells are more totipotent...the issue is...they are also much younger and do not properly integrate into the body...you have to first take the ES cells, differentiate them into the tissue you want, and then implant that tissue...with cord blood you are more relying on the cytokines produced by the cord blood to help the body's own stem cells cause regeneration...if you do go for ES tretment...please keep us posted...

[pvdxtc]

@cellmedicine Ok, I see exatly what you mean.....do you have another way that I can contact you besides youtube chat? I would like to ask you a couple of questions.

[cellmedicine]

@pvdxtc for sure, you can simply email me at thomas.ichim@gmail.com, im always very busy so if i dont respond, dont hesitate to email again

here is my number 858 349 3617

[AWDESIGNS8]

HOW MUCH DOES THIS COST ITS GREAT BUT IF YOU DONT HAVE THE MONEY YOU GIVE FAUSLE HOPE LIKE FOR MY SELF I DONT HAVE THIS MONEY

[largefolder1977]

Had a neighbor who went to an Asian stem cell center... and their condition REVERSED! It was AMAZING! They got a stateside evaluation thru SCC International (weblink is sccinternational-dot-info). Why doesn't the U.S. have this?

[BioEDENMexico]

Hi. What do you think about DENTAL MESENCHYMAL STEM CELLS ?

[stemcelltelevision]

tooth derived mesenchymal stem cells are very good for neurological applications.

[BioEDENMexico]

Did you use Mesenchymal stem cells for this treatment?

[cellmedicine]

The patient received mesenchymal stem cells

[vacationpay360]

Awsome news for M.S. What country did you go to get the stem cell treatment?

[tremich]

RealTalkinMom, I know people 15 years out with a bone marrow transplant and no attacks. You explain that?

[tremich]

I went through a bone marrow stem study for MS myself and I am two half years out. I lost my legs 8 times. Now I can walk and run. This was a blessing because my body rejected all medicine for MS. I did not have the best out look of where my diseases was heading.

Novella1229 have you been through one? Have you had some close to you go through one? Are you a doctor in this field? Answer these question and tell me if you can say for sure someone is not healed.

[labernitrum]

how did you manage it to be chosen for the study? ive lost my legs twice already and im no more than 18 years old. i can walk and run now too but my right feet and hand are both rather numb.

[Ingaforemost]

The science behind mesenchymal stem cells for MS is so solid that Phase III should not even be required.

[cellmedicine]

For graft versus host the company Osiris has completed patient enrollment in the Phase III and luckily will have a mesenchymal product on the market early 2010....unfortunately it will likely be a while until approval for autoimmune diseases is given...Celgene just started a Phase I with their mesenchymal stem cells.

[emirapper]

great work from israel coming out on bone marrow stem cells for multiple sclerosis

[sameerazad]

I HAVE MS and I am cured now without stem cell!

[skatergirl333]

cool... but for those of us who are not as special as you...

[nofreakinusername]

you can have no symptoms for years but that doesn't mean you are cured

[cellmedicine]

Indeed, however you may want to see a recent paper using adult stem cells clinically for neurodegenerative diseases published by Slavin's group from Israel.. Slavin S et al. The potential use of adult stem cells for the treatment of multiple sclerosis and other neurodegenerative disorders.

Clin Neurol Neurosurg. 2008 Mar 5

[chrissyb82]

I have MS too - i didnt know it could be cured ! - how ??

[sameerazad]

I found out a doctor in India and ad to go there, to his hospital, he is doing ayurvedic therapy, which is natural therapy no fukd up shyt frm the hospital or the medicines

[chrissyb82]

Thankyou for your quick response - i looking through the net at ayurvedic therapy now - it seems to have centres in the UK - is it expensive? how do you know your cured ? thanks again -

[sameerazad]

because i was paralyzedd from the left side now the left side is the strongest

[RealTalkinMom]

You are probably in remission but you are not cured. There is no cure for MS.

[cellmedicine]

Without placebo controlled Phase III trials it is impossible to say what is a cure our not given the large rate of remissions that occur in multiple sclerosis.

[RealTalkinMom]

There is no known 'official' cure announced by the US at this time. If you had a procedure outside the US because it is not approved here yet means just that.

To misrepresent something that millions pray for the end of is cruel. LAWS in my country (don't know where you are) are set up to protect us.

If you had a procedure which works for you. Good for you really. If it has to do with stem cell medicine then fight like hell, get our laws changed.

[cellmedicine]

A cure is not possible with placebo controlled clinical trials called "double blind" trials in which neither the doctor nor the recipient know what is being administered.

There is a reason why some patient have what is called "relapse remitting"...they do have remissions. The point was made that without extensive followup it is impossible to talk about a cure

The US FDA has protected us from thalidomide through the need for detailed data. We agree with your points.

[AWDESIGNS8]

@RealTalkinMom I AGREE WITH YOU I HAVE MS AND THAT DOESNT NOT GIVE ME HOPE BECAUSE I DONT HAVE THE MONEY BRING IT TO THE U,S,A FOR US 

[Novella1229]

There is such a thing as hope. Nothing is impossible, there is always a way, whether it is in our reach right now or not.

If one believes they can not be cured, they never will be. It all has to do with mind set and having a little hope. Negativity will only make things worse.

[RealTalkinMom]

I've had MS for most of my life.. I'm not negative, I just don't agree with misleading anyone. I don't know where you live but here in the USA we have the FDA which protects us from medicines that might hurt us if it's not tested as much as possible. There are a lot of newly DX young people, teens even and they deserve the truth from those of us who have been there the longest. Stem Cells are our main hope. I've supported Stem Cell Research since day one. It's almost here.

[Novella1229]

I live in the US, and am a teen who as MS. I also work for the MS society. Stem Cell research is looking like the best bet, but there are "vaccines" currently undergoing trial. They are all in phase one right now I believe.

[RealTalkinMom]

I give you much credit for being a teen with MS. My neuro doc talked me into a 'brand new' ms drug, long story, it almost killed me. I still may loose my leg, my primary doc,in the same group, told off the neuro,he didn't discuss it with him. Just becareful. I had ms most of my 51 years apparently and if you were to know me, you would know I'm not a person to mislead. BECAREFUL. You are very young and we are very close to see stem cells in your lifetime. Wait for them, not the vaccines.

[Venom7707]

Where is this cellmedicine could someone please tell me??? thankyou

[emirapper]

Cellmedicine arranges stem cell therapy only to qualified clinics. You can go to the website and call if you need specific locations. They arranged my friend to get treated in India with some interestingly positive results (heart failure).

[jermeal385]

what website or number for the stemcell i have ms

[lighthouseshines]

touching. good to see people are working on taking this to the clinic

[ahmedinho2006]

hi i have ms

and i right now i feel heaviness in the walk

and numbness in like 75% of my body

i just want to know does numbness stays or goes away?

bcoz its now like 3 weeks and more

and it started make me little depressed

i took steroids in saline and now in pills

but the numbness still there though its less than before the steroids.

[ameeek]

The science behind mesenchymal stem cells for MS is so solid that Phase III should not even be required. Osiris should ask the FDA to go on a Phase II with supportive data from their phase III Crohn's trial

[TheVoyager92]

ClinicalTrials*dot*gov is currently recruiting. Dr. Burt at Northwestern Memorial Hospital Hospital works w/many autoimmune diseases by knocking out immune system & rebuilding w/patients own cells.

[christineball33]

Dr Burt's approach is stupid. Do you want myeloablation so that you can die from an infection? or wouldnt you just rather have mesenchymal stem cells without immune suppression?

[AnnOnimousiAm]

There ARE risks to this method - but, this is the best method known for 'fixing' the immune system from eroding nerve's sheath. The disease's symptoms manifest because demyelination is faster than remyelination. In addition to it being impossible to replace all the body's nerves with functional ones, you have to stop the destruction or you're spinning your wheels. Embryonic stem cells are not the answer; we should focus on better immune resets.

[stemcellpatents]

ABSOLUTELY IMMUNOLOGY HAS TO BE FIXED...First of all I dont think Cellmedicine is talking about embryonic stem cells but mesenchymal stem cells. MESENCHYMAL STEM CELLS SHUT DOWN TH1 RESPONSES SELECTIVELY AND ARE KNOWN TO CAUSE UPregulation of T regulatory cells.

Administration of mesenchymal stem cells is a much safer way of reprogramming the immune system of an MS patient. I am willing to argue anyone about that.

[AnnOnimousiAm]

When mesenchymal stem are transplanted they migrate to the myelin damage and differentiate into the cells that create new myelin to protect the nerve fibers. I love 'em and don't want to argue there. What is (journal) evidence of selective TH 'shut down' and how relevant to MS?

[troopermission]

Th1 shut down

- Batten et al. Tissue Eng. 2006 Aug;12(8):2263-73.

- Nauta AJ, Blood. 2007 Jul 30; PMID: 17664353

- Wolbank S, Tissue Eng. 2007 Jun;13(6):1173-83

- Bocelli-Tyndall C, 1: Rheumatology (Oxford). 2007 Mar;46(3):403-8. Epub 2006 Aug 18

[troopermission]

Good review on Th1 causing MS. Its actually Th17 and inflammatory processes. But this should be a good start.

Weiner HL.

Related Articles, Links Immunosuppressive treatment in multiple sclerosis.

J Neurol Sci. 2004 Aug 15;223(1):1-11

[karena321]

What you are saying is exciting, however, let us see you WALK!! My MS has affected my balance, and my perfectly erect walking. I never have had pain, only muscular pain due to my trying to use my limbs, and arthritic pain of my phalanges, which ultimately, I feel is due from my drinking sodas. Even though I believe in stem cell help, and I DO WANT IT, I believe that federal funding will pass for stem cell research and therapy, so that the disabled will be abled again.

[stemcell5]

I agree! Go to Costa Rica and take a chance. I'm sure glad I did!

[troopermission]

This is amazing !! I like the fact that your not like other stem cell promotional sites but you actually give out useful info

[ishtrice]

where is this institute?? as i have ms also n iam very interested

[christineball33]

they have a website if you google cellmedicine

[stemcell5]

The institute is in Costa Rica! Great Doctor's!! Cleanest hospitals I have ever been to and I best most compassionate care I have ever received. Diagnosed in 2000 so you know I seen my share of hospitals and Doctors. My Doctor in the States in actually waiting with anticipation to see what these stem cells will show in the MRI in November. Great to have a good Doc on your side here!

[christineball33]

Has this patient recieved bone marrow transplant? These procedures are dangerous since the original bone marrow has to be irradiated and destroyed, leaving the patient exposed to opportunistic infections before the new cells are put in.

[cellmedicine]

No. The patient was treated with mesenchymal stem cells in absence of conditioning. This is safe.

This is the same type of stem cells currently used in Phase III clinical trials in the US for GVHD and Crohn's by Osiris.

I agree that bone marrow transplant has the possibility of causing severe adverse effects.

[stemcell5]

My bone marrow was not irradiated and destroyed, but what I can tell you is I am not longer on MS medication. I walk, talk, read and I'm awake all day! It is fantastic!

[jonlamarre]

I think the results of cellmedicine's work was phenomenal.

[stemcell5]

I agree! Go to Costa Rica and take a chance on stem cell -- I'm sure glad I did!