Muscular System, Neuromuscular Junction

[sy2626sy]

thanks for the animation..it helps for my task.. :)

[sy2626sy]

thanks for the animation..it helps for my task.. :)

[ram333able]

they skipped the role of calcium maybe because they think the viewer should know it already either way ADDED HERE**************

Action potential travels down the axon ends in the pre synaptic motor axon termina and opens voltage gated CALCIUM CHANNELS

the increase in Ca2+ permeability of the axon terminal causes an infflux of Ca2+ into the axon terminal . the rise is Intracellular free Ca2+ causes the release of acetylcholine from synaptic vessicle into the synaptic cleft

[TheDemonVeen]

@ram333able Pretty sure he meant the role of Ca2+ in muscle contraction

[VidUploDer]

easy general information but not so deep

thanks

[mattmufan]

I kept thinking this video was pausing to load..

[pauljb07]

Animations are great but why does every single person who narrates them has the amazing ability to put anyone to sleep.

[marlekoliko]

hahaha the muscle contracting at the end. lucky they put that in there othewise we wouldn't understand/believe it.

great explination though, really helpful :)

Invagination!

[AlucardCrazy88]

LMFAO AHHAHAHAHAHAHAHHAHHAHAHHAHA "ivaginates"??? AHAHHAHAHAHAHHAHAH ROTFLMFAO I'm sorry thats just too funny!!!

Well I think this guys mind was somewhere dirty when he narrated this :P

[wo0olie90]

Role of calcium??

[mamahv]

calcium plays a role later in the actual contraction of the muscle by binding at troponin which reorientates tropomyosin, uncovering the myosin binding site. There is a great video for this process as well.

[wo0olie90]

@mamahv hey, where can i find that video?!

[GodDamnit7711]

My teacher says envaginate like 34 times ever lecture.

[DevilDman]

@GodDamnit7711 It should be innervates...

[paquito91]

aaaaaaahhhhhhhhhh!!!!

[JimmyD0YLE]

my favorite part of this video is 1:23-1:25

[TheJebalo]

@JimmyD0YLE y

[JimmyD0YLE]

@TheJebalo the animation of the muscle contracting made me laugh for some reason. it was like 4 months ago I dont remember why I thought it was funny

[dewdrop16]

woahhhh slow down!!

[merdhater]

how the anticholinergics blocked the neuromuscolar receptor of the acethicoline?

[greencoveredbridge]

Good video. One note though, my textbook says that each muscle fiber (cell) is served by only one synaptic terminal. It says that each axon meets the muscle fibers (not physically touching) near the center of the muscle, and that the terminals of an axon serve fibers spread throughout the muscle...they do not serve a clump of fibers close together in one part of the muscle... and one terminal per fiber. The illustration in the animation does not show this.

[ruedjgtc]

@greencoveredbridge I think he did eventually show the neuromuscular junction, i.e. the invaginated region. The beginning animation shows a ambiguous color choice that is misleading about the proximity I think.

Innervation is different depending on the level of neuronal requirement. That in your thigh there is a main alpha neuron that takes care of the initial signaling, as basically shown with the video. What is missing is electrolyte signaling, t-tubules, RMP, but the video serves its point

[kvmzot]

Great movie, but opening of the gate in the nictoine acetylcholine receptor, requires the binding of 2 acetylcholine molecules , instead of 1

[speedracer612]

Posted by James H

[jeff8605]

Theres no mention of Ca2+ ions in this video, because its strictly talking about the neuromuscular junction. It could be argued that Calcium plays a role in sliding filament theory.

[MissyKitty777]

@jeff8605 actually, Ca2+ ions are involved in the neuromuscular junction in the sense that when the action potential reaches the terminal end of the axon Ca2+ voltage gated channels are activated which causes an influx of Ca2+ into the nerve which in turn will cause a conformational change to promote the release of the neurotransmitter vesicles.

[kvmzot]

@MissyKitty777 a conformational change into the synaptotagmin, that then triggers fusion of the vesicle

[callmeekay]

I think that you should`ve included the fact that the DNA strands contradict with the flimmabobber, and then the flimmabobber does the worm into the esophagus, creating a chemical reaction to the nerotricularnervesazema system. These acts have been recognized through the American Association of Science, America, tested by number one scientest Robert Creamer.

[MovingUpp]

@callmeekay lol

[ibdorkie]

fuck you all nerds

[JinXuanJun]

we'll be treating you someday if you run into a medical issue

[gemglass88]

No mention of the vital role of calcium????

[Ragaapoo]

TRUE!

[largra]

@gemglass88 The video was about the neuromuscular junction, not a full walkthrough of an Action Potential..

[jemaya123]

@gemglass88 this is just in the neuromuscular junction. Calcium has a vital role inside the cell and not in the neuromuscular junction

[DevilDman]

@gemglass88 You only need to mention calcium for excitation, contraction and relaxation of the muscle fibers. Not for the neuromuscular junction....

[pirocanac93]

@gemglass88 this is part called neuromuscular junction, not muscle contraction :D

[susyysus]

Ineed an animation about smooth muscle contraction can anyone help me please??

[Darkony]

Nice video, but what about the Ca+2 ions function ?

[katrinski]

and how it aids in the release of neurotransmitters ?

[bwhugul]

That's a good point actually!

I guess that this video focuses only on the synapse that starts the action potential in the sarcolemma of the muscle fibre.

It doesn't go any further than the sarcolemma.

If it were to include calcium ions, it would have to include the T tubule followed by the sarcoplasmic reticulum (see page 307 of Fundamentals of Anatomy and Physiology by Martini, 8th edition, published by Pearson)

[jhayes1204]

exactly

[rb19760]

'invaginates' is such a great word!!!

[Amar90]

@rb19760 hahahaa the second he said the word its all i can think of

[drdannyroks]

good

[AyQueChiquita]

sweet!

[rgz1985]

Mike esp sent me this video

[bo3alwa87]

Thanks for uploading it :)

[zulufirebolt]

majestic.

[shhhiiio]

Great video, very well explained.

[AlbertolinoAlves]

Well done!!

[nmjunction]

Nice! Very informative. Great graphics