Central Dogma

[xenabss]

very good, really liked it

[dapiridoob]

THE ONLY DOGMA I BELIEVE IS IN CENTRAL DOGMA! :D

[hongmancho10]

this is by far the best molecular biology video i have ever watched. I wish they just turn on this video instead of teaching in the molecular biology lecture.

[jrlmenezes1]

the translator got it wrong. The central dogma is from 1958 not 1985. And in 1958, the code wasn't broken yet. So the transfer rna and messenger RNS were not even figured, only that there were intermediaries between dna and protein. Incredible feat. By 1970, more was know and the "dogma" was reiterated in its present form

[hahaOSAMAhaha]

@jrlmenezes1

[Cannibalope]

Why does Japanese make things sound so much simpler? Yay for this video

[dumtadum]

yes, if you want a reference I recommend the cell for further info on intracellular mechanisms I recommend Molecular Biology of the Cell.

[YurNotSpecial]

@dumtadum I would recommend looking into it! Specifically regarding this statement: "tRNA is a protein..."

[Stupidespeon]

oh, good, and asian person. Now I can't fail my biology final!

[dumtadum]

A prion is a specific non-productive way of folding a protein that facilitates the process of other proteins to fold the same non-productive way, ie it is a self-replicating process.

Prions became famous because of the mad-cow disease, scrapies and creutzfeld-jacobs disease, since prions are the most likely cause of those diseases.

[bluejello007]

A 13 week class condensed into and 8 minute video...

[kendonator1]

I hate to ask, but am I the only one to get the Evangelion reference?

[misshayleygirl]

Such a great review for my exam tomorrow! Glad I found this :)

[olga2415]

The central dogma of Cricks theory of the DNA double helix has been fatally challenged, yet the new discovery has not been publicized because science has been compromised by the politics of greed. Now mankind must deal with genetically modified foods that is already showing signs of catastrophic random altering of the DNA of all plant and animal life on the planet. Mankind needs to develop a bit of humility. Our leaders have gone mad and we admire them.

[psychosavant]

@olga2415

Hold on.. if it's not been publicized, how do you know about it?

[olga2415]

@psychosavant CLEARLY, I mean that the Crick gang has not acknowledge that the central dogma is flawed and it has not officially recognized that fact so, continues to promote the dogma as truth, Perry Mason.

[psychosavant]

@olga2415

You think the one way travel of information from DNA to protein is a lie based on a worldwide scientific conspiracy? It's not possible AT ALL that it's based on mountains of data and countless man hours worth of hard work and research from thousands of educated scientists.

But I still don't understand how Perry Mason is involved, and I'm still curious to know how you managed to learn about this new discovery that fatally challenges this theory. Can you present your case at least?

[olga2415]

@psychosavant I was researching GM foods and it mentioned the central dogma and how erroneously it proved to be. The information is all over the internet and YouTube but it would take me too long to specifically name the items or videos. Do your own research, please. If you cannot make the tiny leap onto what I meant by calling you Perry Mason, I doubt you would understand any explanation I could make about my position re central dogma. People like you enfuriate me with your obfuscating doubts.

[psychosavant]

@olga2415

By the way, I've already found the portion of the article where central dogma is mentioned, and the writer of this particular one got the definition of central dogma incorrect and it defeats the idea of contradicting the principle. If this is the general consensus of your ideas, I encourage you to make additional efforts into finding out how accurate the information in these articles actually are. Either way, I will continue looking into it.

[olga2415]

@psychosavant The thing Crick didn't count on was that the DNA doesn't always only replicate itself predictably, but it replicates whatever cell it penetrates....this is as close to my concern as I can explain. I am not trained in this field enough to recognize whether the central dogma was understood correctly by the writer of the item you read or whether his error defeats the idea. I appreciate your zeal in getting to the bottom of the issue.I will review my own documents and continue to seek

[YurNotSpecial]

@olga2415 "The thing Crick didn't count on was that the DNA doesn't always only replicate itself predictably, but it replicates whatever cell it penetrates..."

What do you mean by this statement?

[olga2415]

@YurNotSpecial I mean, that Crick discovered a definite indeterminism in the way the DNA replicates. The closest anyone can get to predictibility of anything on the subatomic level is probabality, not certainty. There will never be a mathematical formula for everything that is seen to have happened, is what his discovery unearthed because there is too much that is unpredictable. Creativity is not something that can be quanticised. Is this the way you understand it also?

[YurNotSpecial]

@olga2415 What are talking about? There's a lot of ambiguity and generalizations in your comments, please be specific.

I was hoping you could clarify this statement more: "... but it replicates whatever cell it penetrates..."

[olga2415]

@YurNotSpecial If I understood it better, I'd be able to be clearer about my statements. lol I am struggling to understand the conflict between Crick and some of his critics. It seems important to some who write their papers. I tried to find the hard copy I have of a site on the issue and tore up my computer room files and cannot put my hand on it. I know I have it somewhere. It was an article regarding HIV/AIDs issue and they harked back to Crick's DN A "flawed" replication dogma.

[YurNotSpecial]

@olga2415 Kinda hard to agree or disagree when no argument has been put forward; although, this statement is a bit telling: "It was an article regarding HIV/AIDs issue and they harked back to Crick's DN A "flawed" replication dogma."

Please bear in mind the central dogma pertains to information flow in a cell, not replication.

[olga2415]

@YurNotSpecial before a cell can replicate there must be information flow; right? I am not a trained physicist and am not looking to be agreed or disagreed with. I am trying to understand this issue of why I am reading so many articles criticizing Crick's explanation of DNA re not only replication re HIV/ AIDs, but genetically modified foods issue. It is complicated to the point that not even physicists agree; why would I deign to look for an agreement or disagreement here on the comments site?

[olga2415]

@YurNotSpecial Yet, Crick did not reveal this aspect of his discovery....that was left for his critics to publicize.

[psychosavant]

@olga2415

Actually, saying recent discovery is far more vague than mentioning GM Foods. Thanks for taking the time to at least mention it. Since you finally did, I was able to look it up. I'm guessing you presumably thought I was psychic. So given this new information, i'll look into it further.

But seriously, it would take you too long to list your sources? Try this: gmfreecymru d o t org

See how easy that was?

[olga2415]

@psychosavant I do not have the obvious need you display to one-up anyone to prove how intelligent I am. Have a good time with your research. I use a wide range of sources, tending to eschew official sources; which I do not trust.

[psychosavant]

@olga2415

This isn't a question of proving how intelligent any of us are, but rather coming down to knowing what the truth is. I'm personally not okay with people wandering around with false information, or even worse, spreading false information. I'm positive you feel the same way or you wouldn't have made your posts in the first place. At any rate, I'll sift through as much stuff I can, and see if I can get to the bottom of this. If there is substance to your arguments, I will find it.

[olga2415]

Anyone know what a prion is?

[davidkeys100]

I got 300 XP points playing this game! Using this Move. I love Final Fantasy... wait

[davidkeys100]

I got 300 XP points playing this game! Using this Move. I love Final Fantasy... wait

[missypunkrocker]

@asddge isn't it Japanese?

[rifliflih]

exellent j'en suis pantoise.

Un grand merci jolie voix

[MrWaffleman098]

Addresses all the right questions....epic

[steppinithotter]

Excellent. My lazy biolgy teacher should watch this. Good work.

[manualLaborer]

i just saved myself 6 years of college with this 8min video.

[Mefis2feles]

did anyone else thought of evangelion?

[WaterBearer2008]

This is wonderful. I am now taking Freshmen Biology and this also helped me wayyyy better than the instructor. I have 5 pages of notes and still didn't understand it, but now it is crystal clear. Visual learning is my forte. Thank you again!!

[nilahable]

yeah, maybe its such a brief explaination, but it does help for further understandings.

arigatou gozaimasu!

[mdoerkse]

How is tRNA made?

[dumtadum]

@mdoerkse tRNA is a protein and made like any other protein. An organism's first tRNA is inherited from its mother.

[YurNotSpecial]

@dumtadum "tRNA is a protein and made like any other protein."

Are you sure about that?

[fkurbanov]

すばらしい　感動的な　まとめです！

天才！

[ThePhakarat]

ชอบค่ะ แต่ฟังไม่ออก อิอิ

[Aire26]

This was terrible I thought, and I'm not being raciest. I just though he didn't go in depth with particularly any of the enzymes or specific tRNA molecules. Hands down the worst explanation I've seen.

[FissionNonStop]

@

obvious troll is obvious

[pinkpendant]

ありがとう!

[dolly224]

very precise xplanation, love it............

[MELODY7809]

この　ビデオは　おもしろくて、　よかったです。ありがとうございます。

So interesting, and well presented... excellent! thank you very much! :)

[harajukulovergirl]

Very good animation and explanation!

[carrishayn]

thank you for this super version of DNA synthesis! It's the best I've seen so far! Thanks for the translation!

[SatoTM3]

so the whole process we just viewed is seen as an old concept? D: or what? confuzzled.

awesome animation. i LUV japanese

[rifliflih]

Wouaaaaah bravo magnifique!

Merci

[rfa123c]

Great vid. Thanks

[Lima547]

Japan!

[salemaw]

i wish all lectures were this good!!

[nsubashcbose]

Really fantastic..Pls promote videos like where students can understand very easily than reading text books.

[madmercenary2]

Was very informative. Covered the topic very well.

[barrooooz]

I'm so afraid of my molecular bio exam..........

[spiryt03]

@barrooooz, how did you do?

[RobotBadger]

domo arigato gozaimasu! ^____^

[MrProper2009]

ATCGATCGATCGGATGCTATGCTATAGCCA­TTA  3:32 right?

[goumjandi]

this is a great video ^^ thanks

[illraveu]

this is the best desciption ever!!1 :) what is the official name of this video so I can download it in HD quality? maybe some 720p torrent ? or Rapid share? Good Job

[lactatingwalrus]

close enough

[jaymadison1309]

This was really great. Thank you!

[cherryquf]

life's amazing and beautiful. i love how everything is so accurate.

[coolguy0529]

Super video!!! Hard to believe:)

[Ryukazaki]

1:48 Just like some creepers?

[cjlouis1029]

This is super awesome. Helped me understand way better than my professor explained it and SI Instructor. Very simple and accurate and wonderful animation that captured the processes in fine detail. This is why I love the Japanese.

[7410n0]

Don't be so hard on your professor. You probably just understood it this time because of the visual aid

[Underfaith]

@cjlouis1029 Admittedly my beliefs exactly as why they are more advanced.

[ananiasacts]

It would be nice to have a hierarchy of interlinked videos to allow viewers to zoom into the many different processes involved in great detail. Perhaps even down to the level where only a single active site is shown and some sense of the many hundreds to thousands of wrong or misaligned molecules that bounce in and out before the correct one creates a reaction is depicted. Perhaps something like the encyclopedia of life, but for just for the various nanobots that inhabit our cells.

[1derfulymade]

simply wonderful :)

[Techra]

excellent. i love the "natural" explanation of things, such as giving an idea of how fast the RNA polymerase process works

[spiryt03]

@Techra yeah, definitely loved the time reference.

[ambiemouse]

that helped me so much for my quiz tomorrow :D

[xMiro7x]

lol me tooooooooooooooooo

[betomondra]

very interesting to undeerstand DNA functions

[TsimNujHawj]

Great video. Japanese narration makes it more majestic. :]

[durstwurst]

great video & translation.

[Essincy]

this really helped me..cheers!

[alheadbme]

よかった。

[Shaun32887]

Those are pretty pictures...

[dfernan]

Wow!

[spyxter]

AMAZING.

Just amazing.

[bluedrangon69]

this was really helpful

thank u so much for uploading this.

[neithere]

Fantastic. Thanks a lot!

[Imbacrap]

detailed....

[mercychen]

nce!!! it is so detailed.........ü

[2soos2]

wow, great video

explains all the concepts with really explainatory images