Luckily, this substance is one of few that occurs in nature. All you have to do is extract it as opposed to synthesizing it. Also synthesizing N,N Dimethyltryptamine is a TON of work so you might as well start with tryptophan. Synthesizing 5-MeO-Dimethyltryptamine might be a little easier considering most (as I like to call them) "teenage hippy organic chemists" will want to take a complete synthesis route just to see if they can do it. I did too when I was 16....
thank you very much. But can i reduce the carbonyl groups with NaBH4 instead of LiAlH4??? the first one is currently in my arsenal whereas the second is not...
Nice post. Could you post the mech from tryptophan viatetralin and sodium cyanoborohydride? Also would it be possible to decarboxylate tryptophan using Hunsdiecker reaction and then n-methylate. Im not aware of any N-methylation reactions outside of enzymatic reactions.
@bryantm6 I posted a video going through what you suggested. I don't believe tetralin could have any part to play in the mechanism, looks like a solvent to me.
Luckily, this substance is one of few that occurs in nature. All you have to do is extract it as opposed to synthesizing it. Also synthesizing N,N Dimethyltryptamine is a TON of work so you might as well start with tryptophan. Synthesizing 5-MeO-Dimethyltryptamine might be a little easier considering most (as I like to call them) "teenage hippy organic chemists" will want to take a complete synthesis route just to see if they can do it. I did too when I was 16....
JorgeGonzalas 21 hours ago in playlist Uploaded videos
are all of these starting materials un regulated?
sevenwindmills 3 weeks ago
Yeilds quite low on this synthesis i believe
bsboy20 3 months ago
What's the yield?
sigatus 4 months ago
"...about Alexander Shulgin's synthesis of DMT because drugs are fun"
10/10. I lift my hat to you sir.
uchiacon 7 months ago 9
Lol this guy sounds like he does a lot of amphetamines.
normtheclone 8 months ago
Niiiiiice
musacworld 10 months ago
thank you very much. But can i reduce the carbonyl groups with NaBH4 instead of LiAlH4??? the first one is currently in my arsenal whereas the second is not...
Fomelogo 11 months ago
@Fomelogo sodium borohydride is most likely not aggressive enough to reduce the amide.
Fenderson5555 11 months ago
Nice post. Could you post the mech from tryptophan viatetralin and sodium cyanoborohydride? Also would it be possible to decarboxylate tryptophan using Hunsdiecker reaction and then n-methylate. Im not aware of any N-methylation reactions outside of enzymatic reactions.
bryantm6 1 year ago
@bryantm6 I posted a video going through what you suggested. I don't believe tetralin could have any part to play in the mechanism, looks like a solvent to me.
Fenderson5555 11 months ago
He stuttered too much and is SLOOOWWWW
prankcallradio 1 year ago
What type of yield can you get from this synthesis?
jbrown677 1 year ago
whats the outcome? effects wise?
worldchange1 1 year ago
@worldchange1 You wouldn't believe it
mjalloxxxx 1 year ago
Could you repeat that?
andrewyaoauatauabaea 1 year ago 6