Transcription and Translation

[LoveNeverCeases]

Thank you for the helpful video! My Zoology "professor" only spent about 2-3 minutes explaining the whole process (skipping over some parts) and then proceeded to spend 5-10 minutes explaining the simple concept of the phylogenetic tree. I will probably be visiting your videos a lot this semester...

[TheBPNYboyz]

Thanks man

[YomamaBea1]

with this video i learnt more than in one month of school

[jlopes20815]

this was great. thank you so much, keep em coming!

[kimpossible1516]

I understand now! This is very helpful!

[thec0wsaysm00]

the beginning music is epic, btw great job, its all clear to me now!

[zatie921]

i love this tutorial!very helping

[xerojreffaj]

thanks! am learning this for bio component of 1st year optometry BSC and this really helped to clear it all up in my mind

[iranianboy123]

wow, so much easier when someone explains it then u reading the book 100 times

[dannyfresh1111]

awsome very helpfull =)

[TheDonPurp]

THANKS YOU ARE THE MAN

[joyblueeyes118]

I really appreciate this video!!! Just wanted to say that.... and yes, I have a final tomorrow :)

[RlceBowl]

weeeeeeee!!! thank you! exam in 19 hours and this helped alot!

[finalman25]

this would be a lot easier to learn in science books if they typed it in laymens terms

[soloud384]

just read the comments before watching the vid.. and now i have high expectations. THANKS for that!

[bellanstellan]

This video helped a lot!! Thank you!

[lhalliday319]

thank you very much this really helped me grasp the individual pieces better!!! have a blessed day!!

[CHIBIjapapino]

thank yooouuuuuuu!!!

[flylesslife]

thanks this video helped me a lot :)

[XxAnnn]

Fantastic! This helped me sooo much! Thank you!!

[miadarling17]

THANKS!!!!!!!!! I have end of term final exams and my teacher is horrible at teaching + I learn really wierdly. This helped much :D

[99Ownsz99]

is that a dick @ 8:36 ?



[20COLOMBIANITA]

THANK YOU SOOO MUCH!! MY TEACHER CHALLENGED ME TO MAKE A 100 ON THIS TEST AND THIS VIDEO HELPED ME A LOT...I KNOW IM GONNA MAKE IT (HOPEFULLY) VERY CLEAR VIDEO, LOVED IT :D

[tylerhauser711]

this has blown my flippin mind I UNDERSTAND IT NOW:) thank you very much its actually very very very awsome!!!!!!

[arsenal4life911]

Thanks man, this video was perfect, and you included everything that needs to be known. It must have taken a lot a of time, so thank you very much.

[kayrayy15]

thank you! this helps a lot! :)

[KrsnaBhakta]

nice, thanks.



[SoePower]

Even if it's in english and I'm from Quebec, I understood and it helped me a lot. Thaks for your video.

[rldash]

learned what I needed to know the day before my exam...thanks!

[migglep]

thank you thank you thank you thank you thank you thank you thank you thank you thank you

[locdog187]

You explain very well and are patient. Thanks makes sense!

[perseveeruns]

Best video on transcription and translation on youtube! Made a lot of sense!

[dianav2n]

VERY CLEAR AND INSIGHTFUL VIDEO! Helped me understand the concept of DNA replication so much better. I have my microbiology exam in a day and this truly truly helped. Thank you. Everyone, let intelligence prevail!

[XlilGorjustX]

Helped me mucho!!

Thanks = )

[MsTriara]

You, sir, are awesome.

[iSc00ter4lif]

well, its not a minute but its a great vid :D

[RozieeeKay]

your voice makes me feel so calm, and i feel like you're actually explaining it instead of just telling me what happens, which is where my teacher sucks. Thanks for your help :)

[dwilmer7]

awesome video.. i like the 80's infomercial music at the end... 

[PotatisenSimme]

Awesome.Best biology video on youtube

[93yoochun]

this video make me understand completely rather than listening to the lecture everyday.thank you soo much!

[ambertidewda]

I love the dramatic music in the animation!

[ambertidewda]

Thanks! This was great.

[granesele]

This helped alot for a quick review before taking microbiology in college. Thank you!! :)

[Arooba27]

GOD BLESS YOU for uploading this video :)

[teapot12999]

Thank you!

[Jkatsoolis1234893]

it scared the hell out of me at 7:04 . i was watching this at 5,30 in the morning with it turned up so i could hear it.

[B4ndoGor4]

love how it says bio in a minute but it goes for 9.36...

[wklee1997]

awesome!!! SUPER HELPFUL!!!



[forgotmypassword100]

thank you !! really appreciate this vid!!

[PuRPLeTuTa]

in a min? lol

[Neejan1]

Very helpful. Thanks!

[crocodilerachel]

I am a graduate student, and I just wanted to let you know that I am using all your videos to study for my orals - it's been so great to be able to get a quick review on all these topics so that I actually have time to review my thesis proposal and everything else! Thank you for taking the time to do this. Now that I am a TA, I really value all the effort it takes to be a good teacher :)

[skys90]

Thank you!it really help!

[hyroglyphx]

Wow, I was completely lost before you posted this. Brilliantly simple. Thanks

[killeray0]

hey man thanks i have a science exam tomorrow and this helped heaps!

[McCloud95]

W.R. McCammon -- I love you. Thank you, sir.

[2kewl4skoolzz]

More like Biology in nine minutes... just saying

[JoshStroma]

Hey,appreciate you taking the time to make this video, it was very helpful, just like a good lesson :)

I just have one question, there are supposedly free DNA and RNA nucleotides in the nucleoplasm and nucleolus. These nucleotides are activated with 2 phosphate groups attached? What are these phosphates used for, my text book says they release energy for bonding adjacent nucleotides? Is this the sugar-phosphate back bone? Also if mRNA is produced why are there free DNA nucleotides?

Thanks!

[ShaheenShine123]

Thank you so much!!! This is extremely helpful why can't we just use Youtube for school? Honestly my biology book is so incomplete this covers things I didn't see in my text book. 10 minutes of epicness. Thank you sir.

[PenguinMan272]

Wow I can't believe all that was in ten minutes, took my teacher nearly a month to get it all across hahaha nice work

[bleujade]

i'd rather have u as my lecturer ! great explanation ! thanks a lot dude!

[Darklightxxxx]

Very helpful >.< wish my classes were like this

[croiniotis3]

Thanks! Helped me a ton. :)

[Ur0pinionDoesntCount]

siiick

[Lightarkangel7]

man this is soooo going to help me so much, and i have a final tomorrow. this is so easy to understand. thank you

[knprada]

Really great animation!! I was so confused before watching this. Your animation was so much clearer than the process described in my book! Thank you!!

[IMproperSignLanguage]

Why go to class when you can just skip it, sleep in, and watch this more informative stuff?

[Rike1917]

dude, i didnt understand this at all and within the first 46 seconds i understood it thanks!

[tarpon63531]

Very helpful. Thank you.

[Shalini0506]

So useful to understand, amazing. Thanks

[mikemysta2008]

Good vid. hint of advice next time dont put videos up of robots talking. i liked it wen it was u just explaining it.

[seneson]

THANK YOU SO MUCH!

[soccajuggla12]

this video was helpful. Thanxxxx so much :p xoxoxoxoxoxoox

[80overpar]

Very Helpful! My BIO 101 lecture prof is seriously inept, and unfortunately, I have to resort to YouTube for quality lecture vs the class I paid good money for. Pisgahscience is now one if my fave's!!!!

[noname2020x]

I love your movies. You helped me sooooooooooooooooooooooo much!!!!!!!!!1 OmfG I ACED MY TEST YEAY!!!!!!!!!!!!!!!!!

do you want to go on a date?

[xxOn3Lov3xx]

OMG OMG OMG OMG THANK YOU SOO MUCHH!

[Muzikfreak2014]

This was really good! Helped me ace my bio exam! Keep up the great work!

[calypsocastar]

I LOVE THIS!!!!!!!!!!!!! thanks SOOOOOO much! this vid is AWESOME!

[trinichic11]

@calypsocastar ye diz kara btw. bt tnx 4 d tag great vid! :) i find we shudd watch dem in class sumtimes 2 wake us up lol u kno den jst run thru d details quick. d visual rel helpful.

[RacheyG91]

incredibly helpful-especially the animation!

[dangerman07]

thank you so much, that video really helped me understand it all! :)

[Zenome]

Fuck this shitty ass video. It's not college material.

[FFMDiego]

YOU DID A BETTER JOB IN 10 MINUTES THEN MY TEACHER IN A WHOLE YEAR !

DEFINETLY BEST VIDEO ON YOUTUBE....THANK YOU YOU VERY MUCH !

[samounti]

very easy to understand.. this increased my understading, thank youuu :)

[osoflash3]

great job really helpful

[irishballer272]

Thank you!!! Helped for my test. Yeah! Woo! Yeehaww

[Lukeyboi14]

thanks mate, it helped alot, i really needed that good animation as well to understand what my book was saying. :) chrs

[pisgahscience]

@Lukeyboi14

Thanks. Glad it helped! :)

[coylieee]

thank you so much!!!! it helped majorly!!!!!!!

apreciate it alot!

[vishalpoptani]

very nice presentation.

[ohaithurrx]

this is amazing, this definitely beat a day of class. thank you so much for helping me understand it more for my final on monday!

[haesbich]

It is America science so amazing 하하 ^^

[sheena1188]

thank you so much !!

it really helped!!

[funkyVICTIM2]

Im still using this video thanks once again!

[patrickmgao106]

Hey thanx soo much for this vid it helped soo much. I wuz cramming for finals and this video helped clear alot of stuff up :-)

[pisgahscience]

@patrickmgao106 Thanks. I'm so glad it helped!  That is why I'm doing this channel. :)

[haidara10]

good job

[sw33tskyblue0o]

Thank you, it was helpful, Atleast now I dont fail in Biology.

[eimsnic]

sounds like matthew mcconanaughey giving a biology lecture....if only.....

[Jumpthanfall]

this is really helpful! Videos are so much more effective then pictures or a teacher talking about it.

[melody321456]

OMG you don't understand how you saved me!! i think i can finally pass a biology test thank you you saved me!!!!

[funkyVICTIM2]

Thankyou so much you have helped me soo much

all the way from London

[pisgahscience]

Wow, thank you! Doctor Who is my favorite TV show (original and new). I'm glad it helped.

[funkyVICTIM2]

@pisgahscience lol im not the biggest fan of doctor who! Thanks again this video really helped do you have you uploaded anymore by any chance

[pisgahscience]

@funkyVICTIM2 I'm working on three new videos right now. As we get close to the end of the school year, time become short. Hopefully have them posted by the end of the month.

[rachel935higgins]

this was very helpful! but i still have a question, why cant the dna leave the nucleus?? and what would happen if it did?? thank you so much for your help!:)

[pisgahscience]

Well, DNA is a HUGE molecule. It contains way more information than needed to produce a protein. Therefore, the mRNA just transcribes the section it needs (plus a little extra) which is them trimmed down when it is processed. Then it leaves the nucleus.

[cherxy777]

@rachel935higgins And also if it did leave the nucleus then it would be subject to a lot of factors that could damage it and cause mutations in its sequence. It's better off being safe and sound in the nucleus :)

[MissBrittIsBoss]

I sick and missed a huge lecture so this was i HUGE help! I dont even think you can understand how immensly greatful I am. :)

thanks sooo much

[pisgahscience]

Aw, I'm glad I could help! And glad your better.

[jbouge86]

Thank you so much for this video, it helps me a ton!

[thebookisthe]

You said transcription is basically making an exact copy, but it really is not, because the base pair of RNA is not the exact same as the DNA base pair.

[pisgahscience]

True...just like a xerox copy exactly the same as the original. Color differences, tonal differences, etc all make the copy different than the original, but the information encoded is the same, which was the point of the video and indeed transcription itself. While the RNA is processed before it leaves the nucleus, the information contained in it is exactly what should be conveyed to the ribosomes for the proteins. There is some junk DNA that is removed.

[pisgahscience]

That should say "just like a xerox copy is not exactly the same as the original."

[pisgahscience]

So, true. You are exactly right that it really should say "exact" copy. I classic example of oversimplification of a very complicated process. Thanks for letting me know.

[pisgahscience]

Crap...total grammar fail - That should say, "You are exactly right that is really shouldN'T say "exact" copy.

[thebookisthe]

@pisgahscience

You're right...wow that was a dumb remark i had made 10 months ago! I have acquired a great deal of knowledge about the process of DNA replication now, so that's why! Good video, good job with explaining...all makes sense! Thanks :)

[carterj3995]

Awesome! Ive been watching many videos to ready myself for final exams tomorrow but this one being the most helpful! thanks! :D

[pisgahscience]

Aw, thanks. I hope to do more when I have time!

[AinsleyGraceMusic]

this is amazing!

thank you so much, this will make my finals lots easier:D

but i dont understand why A translates into U instead of T.

i know U and A are able to do that, but why in this situation?

[pisgahscience]

Methylation of uracil produces thymine.[5] It turns into thymine to protect the DNA and to improve the efficiency of DNA replication. Uracil can base pair with any of the bases depending on how the molecule arranges itself on the helix, but readily pairs with adenine because the methyl group is repelled into a fixed position.[5] Uracil pairs with adenine through hydrogen bonding. Uracil is the hydrogen bond acceptor and can form two hydrogen bonds.

[pisgahscience]

Uracil can also bind with a ribose sugar to form a ribonucleoside, uridine. When a phosphate attaches to uridine, uridine 5'-monophosphate is produced

This is of course from Wikipedia.

[sweethomie3]

this was good!!!

[sara4542]

very helpful tnx :)

[fendermonkey06]

Haven't watched the whole thing but the first mistake I saw was at the part where you described the codons.

in RNA, T turns into U. Not A to U.

[pisgahscience]

Where in the video is this? I can't find it. If you're talking about the part where I'm demonstrating translation, A binds with U instead of T in the RNA strand. T is replaced by U, but it is complementary to A. Let me know in case I missed the mistake.

[Shinizzle3]

thank youuuu! :D

[metabon]

ready to ace ma quiz today :D

[pisgahscience]

awesome! Good luck!

[1992account]

helpful - thanks for going to the effort.

[TheKyleWins]

Oh... fail... from the thumb I thought it was a game of Tetris...