Thank-you so much! You allow biochemistry to be very understandable! I'm a senior in high school and I can completely understand you and the course! You are a very generous person for allowing us to see your very thorough lectures on Youtube!
Hi Mam,I have a question/doubt..about cysteine amino acid.If cysteine is non polar,how can it form the disulfide linkage which is a covalent bond.Some classifications place Cysteine as an Uncharged polar group.Which do you(or anyone who "knows" biochem) find more appropriate?
All the primary structure are covalent. The Cysteine structure forms in an instance where the Cysteine groups are along side each other from different chains. I hope this helps and just in case, just because something is covalently bound does not mean it will always be polar. For example nitrogen or oxygen gas, although there are two same atom sharing electron they are nonpolar because there is no pull toward one specific atom. They are shared equally
The explaination for histidine's action as either an acid or base catalyst is not 100% correct. The physiological pH does not vary more than 0.1 in healthy individuals. A pH of the bodily fluids under ca. 7.35 is referred to as acidosis. A pH under 6.8 is not consistent with life. The pK of imidiazole of histidine is far from this value, not close as told here. The only way histidine functions as a catalyst is because of the presence of adjacent charged groups in the protein, raising its pK.
Yooo dude rather then complaining y dont u pur forward a video of ur own n then post it around !! This lady did a pretty neat job explaining all these tough shitty stuffs !! So Quit complaining n get to work or atleast be bit more respectful !!!
This comment has received too many negative votesshow
a bit of tattooing with matching skin color will cover all the white patches on this wonderful teacher's face. i hope she considers that. just a suggestion.from medical point of view as well as cosmetic.thanks.
My book is slightly different too but you have to understand that they are all different author and A.A have different properties that make them easy to group in different ways.
most important you have to understand the characteristics of all of them and understand the structure, if you do so you wont be confuse.
I will give u an ex. she group the gly and pro in a unique group, but the gly and the pro are also non polar because of the structure they have and also make them hidrofobic.
in the video HIS is in the polar group but in ur book is in the basic, both are correct because the HIS is a weak base and can participate in polar reactions.
you will also find books that classify some of them as charged this are what she call acids and bases because of the charge of the carboxilic group and the amina group.
i hope this may help u and other with the same Q.
In this lecture the pKa for the R-group of Glutamate is shown on the titration curve as 4.25. In the previous lecture you labeled the value as 4.1. On the internet I found tables listing 4.07, 4.25, and 4.3. Why the discrepancy?
tnx very much this is truly helpful to understand the basics of biology at a molecular level, you have made interesting and easier, now i start understanding pre-much everything.. tnx again.
I know how they fold into the same structure every time .... it's the 'cluster' .... naturally ... see my channel to bring yourselves into the twenty first century
I dont need to go the the univ this women is my biochemistry angel
2fatloss 3 weeks ago
life saver ...love it love it love it love it love it love it ..
carebianmd 3 months ago
This lady is amazingly pedagogical. An angel!
FaerieDust 3 months ago 2
This has been flagged as spam show
you said cysteine is polar in 23.35 in lecture 1 amino acids 1 but in lecture-2 amino acids lecture 2 you labelled it as non polar (21.05)
mrinalbarua 3 months ago
This has been flagged as spam show
you said cysteine is polar in 23.35 in lecture 1 amino acids 1 but in lecture-2 amino acids lecture 2 you labelled it as non polar (21.05)
mrinalbarua 3 months ago
Comment removed
mrinalbarua 3 months ago
CAN I HAVE YOUR EMAIL ID
mrinalbarua 3 months ago
medical schools miss you!!
mrinalbarua 3 months ago
This has been flagged as spam show
You saved me!!
anainesleib 8 months ago
You saved me!!
anainesleib 8 months ago
I love this teacher. What a big heart!
faridaik 8 months ago
This has been flagged as spam show
Extremely appreciated :)
faridaik 8 months ago
Comment removed
faridaik 8 months ago
Thanks for making this almost easy!
Sneery69 9 months ago
thanks for the detailed illustration
sandrathekiller 11 months ago
This has been flagged as spam show
i am a medicine student
your biochem lectures are too good to ignore
can u tell me where can i get similar videos of medical lectures
i need them badly to cope up with my acadamics
dujanahbhatti 11 months ago
Many thanks for making this so simple!
Surfsailwaves 1 year ago
2 people are going to fail the heck out of Biochemistry.
bozez1 1 year ago 2
This has been flagged as spam show
download full lecturer series for every engg. many branchs
: thoughtcrackers.blogspot.com
govinddass012345 1 year ago
good explain
b3d1983 1 year ago
INDIANS ARE VERY INTELLIGENT ..........
THANK YOU VERY MUCH, AND NOW I UNDERSTAND WHAT IS BIOCHEM.....
I AM A FILIPINO.............
COGIE2000 1 year ago 4
Thank you very much Maa`m.....these lectures are very helpful for me...
Thanks again...
MrUrocker 1 year ago
u zavez mah liefz , kthxbai
shafahta 1 year ago
You absolutely saved me, Prof.S.Dasgupta. I thank you for explaining this in a LOGICAL way! Love from New York!!
mrenee21 1 year ago 2
chyoung@pavo.seed.net.tw
chy47 1 year ago
Fantastic lecture series - many thanks.
cjbl84 1 year ago
it was clearer when she wasnt shouting
deefromott 1 year ago
Thank you madam it was really worth for me thanks a lot
vimalgene 1 year ago
Thank-you so much! You allow biochemistry to be very understandable! I'm a senior in high school and I can completely understand you and the course! You are a very generous person for allowing us to see your very thorough lectures on Youtube!
TheViolinguy92 1 year ago 2
This is an excellent job! I enjoyed the two first lessons.
hrfepo1 1 year ago
will you marry me?
SlyMcdoogal 1 year ago 6
thank you so much..
ruluhur 1 year ago
Thaking you-tube and IIT Kharagpur
MrRDX410 1 year ago
i love how she teaches .. holy if i had a prof like her in my school i dont think anyone would have wanted to compete me in biochemistry .. lol
timemuch 1 year ago 2
I dont understand how an amino group in Hydroxyproline bare 4 bonds
jdrokkala 1 year ago
Prof S.dasgupta make a good impression on me ilike her teaching way.she is treasure of knowledge
goapldan 1 year ago
Best lecture ever! Better than my french biocemistry teacher , better than my arrogant german "Profesor" and better than my confused Irish teacher.
I realy had all those teachers and only this online lecture makes sens.
We can realy feel she dominates her matter.And not other wie LOL.
aoifewest 1 year ago
Ya i also like this Lecture.good job
goapldan 1 year ago
great job madam...
anleboy 1 year ago 3
i fell asleep listening to this lecture
nosorog91 2 years ago
@nosorog91
then dont listen
cutey0011 1 year ago
@nosorog91 LOL .. IT IS REALLY MAKES ME SLEEP .. IT HAS SOME HYPNOTIC EFFECTS :P
JGamdi 1 year ago
Hi Mam,I have a question/doubt..about cysteine amino acid.If cysteine is non polar,how can it form the disulfide linkage which is a covalent bond.Some classifications place Cysteine as an Uncharged polar group.Which do you(or anyone who "knows" biochem) find more appropriate?
amritkaur8 2 years ago
@amritkaur8
All the primary structure are covalent. The Cysteine structure forms in an instance where the Cysteine groups are along side each other from different chains. I hope this helps and just in case, just because something is covalently bound does not mean it will always be polar. For example nitrogen or oxygen gas, although there are two same atom sharing electron they are nonpolar because there is no pull toward one specific atom. They are shared equally
ballsoffury4 1 year ago
great teaching style
aljaesson 2 years ago 2
Hi Professor, your lectures are great!
When you repeat the same concepts again and again, it helps me memorize them immediately. Thanks again for helping us.
pilotmeyy 2 years ago 3
i feeel sleepy listening to this, but really good lecture. i like your explanation. its just a lil too slow for me tho. but alot of information.
thanks alot for posting this up!
djdesh7 2 years ago
are we in the middle of the video lecture era?
angelmdj23 2 years ago
Good job!
eddynorm 2 years ago 18
The explaination for histidine's action as either an acid or base catalyst is not 100% correct. The physiological pH does not vary more than 0.1 in healthy individuals. A pH of the bodily fluids under ca. 7.35 is referred to as acidosis. A pH under 6.8 is not consistent with life. The pK of imidiazole of histidine is far from this value, not close as told here. The only way histidine functions as a catalyst is because of the presence of adjacent charged groups in the protein, raising its pK.
lilleboff 2 years ago
Yooo dude rather then complaining y dont u pur forward a video of ur own n then post it around !! This lady did a pretty neat job explaining all these tough shitty stuffs !! So Quit complaining n get to work or atleast be bit more respectful !!!
TruthExposed123 1 year ago 2
xcellent i wonder what you are doing in india come to america
mirabeaubapi 2 years ago 2
excellent, huge thanks, really supplemented my lectures and lab perfect
sedicirich 2 years ago 4
Good video, but I think the coloring of atoms in models has changed
quefnot 2 years ago
clear, concise, and informative. easy to understand even for a neophyte like me.
cnordheim 2 years ago 5
She is amazing :)
sheerpink88 2 years ago 6
She is wonderful and these videos are great. I have learned so much.
Thank you for posting this wonderful material.
WomenPR 2 years ago 3
This comment has received too many negative votes show
a bit of tattooing with matching skin color will cover all the white patches on this wonderful teacher's face. i hope she considers that. just a suggestion.from medical point of view as well as cosmetic.thanks.
srinivassiddarth 2 years ago
From a medial point you have no idea unless you've examined her in person.
From a cosmetic point of view is from where you argue.
She looks perfectly fine and needs nothing. Who says we all have to look the same?
johnbharris 2 years ago 4
fuck off she is a godess
quefnot 2 years ago 6
i think you have forgoten the aromatic groups with Phe, Tyr and Try!!
myosotiss02 2 years ago
Those were in the last video...
princeofautumn 2 years ago
lol true. I think you forgot video 1 of this series:)
jamesfitness 2 years ago 2
Thank you for this and all the other videos. They are very helpful. Please post more.
WomenPR 2 years ago
okay so in my book the 20 amino acids are put in 4 groups which is different than what is shown in the video. this is confusing me!
neutral nonpolar amino acids
-glycine, alanine, valine, leucine, isoeucine, phenylalane, tryptophan, methionine, cycteine, proline
neutral polar amino acids
-serine, threonine, tyrosine, asparagine, glutamine
acidic amino acid
-asparate, glutamante
basic amino acids
-lysine, arginine, histidine
dreamonlittleman 2 years ago
My book is slightly different too but you have to understand that they are all different author and A.A have different properties that make them easy to group in different ways.
most important you have to understand the characteristics of all of them and understand the structure, if you do so you wont be confuse.
mara0383 2 years ago
I will give u an ex. she group the gly and pro in a unique group, but the gly and the pro are also non polar because of the structure they have and also make them hidrofobic.
in the video HIS is in the polar group but in ur book is in the basic, both are correct because the HIS is a weak base and can participate in polar reactions.
mara0383 2 years ago
you will also find books that classify some of them as charged this are what she call acids and bases because of the charge of the carboxilic group and the amina group.
i hope this may help u and other with the same Q.
mara0383 2 years ago
In this lecture the pKa for the R-group of Glutamate is shown on the titration curve as 4.25. In the previous lecture you labeled the value as 4.1. On the internet I found tables listing 4.07, 4.25, and 4.3. Why the discrepancy?
privatekept 3 years ago
tnx very much this is truly helpful to understand the basics of biology at a molecular level, you have made interesting and easier, now i start understanding pre-much everything.. tnx again.
Assmara 3 years ago 3
I cannot search lecture -3 ? Maybe Protein structure 1? Thanks.
BodeHaryanto 3 years ago
realy is anice and an excellent explanations,God bless you.
alaaraki70 3 years ago
This video can not be played. It gets stopped after few minutes. Any guidance please.
Dr. Shafqat Nazir Senior Lecturer Biochemistry Deptt. Quaid-e-Azam Medical College Bahawal Pur Pakistan +923146860798 (cell)
shafqatnazir 3 years ago
I know how they fold into the same structure every time .... it's the 'cluster' .... naturally ... see my channel to bring yourselves into the twenty first century
Regards
Coo
CooeeEcho 3 years ago
Thanks for using Youtube for such a great cause: Sharing knowledge.
harreaza 3 years ago 36
In anfinsen's experiments we reduce using BME and unfold using urea! cool!
AnatomaniaK 3 years ago