Is IT ready for the Dreaded DNA Data Deluge?

[gadionson1]

truthful ..

[Melki]

truste would love this idea

[Pellionisz]

Young T. Ryan Gregory launched a career on "Junk DNA" (minimizing that Ohno declared a majority of human DNA "to do nothing"). Now TRG is trying to "fuzz up" his stance. Formerly, TRG bunched up with a Lonely Moron full of junk, who still clings to that silly notion. No longer - TRG also dropped "anonymes". While trying to salvage his career launched on "junk DNA" TRG is now playing both sides of the fence; thus his recent entries are rather confusing. He is welcome to clarify. - Principals Only

[St4791]

This presentation is eye-opening for those who no longer wish to hide their heads in the sand. The aim of his talk is not to intimidate, but to enlighten and instill hope. Pellionisz single-handedly drags the audience into the future where the merger of genomics and IT will save and improve lives. The revolutionary ideas he presents are often attacked by cynics, but as Albert Einstein once said: "Great spirits have always encountered violent opposition from mediocre minds"

[JohnnyBananas802]

What do you think Einstein would have thought about engaging in historical revisionism to make oneself seem more important and 'cutting edge'?

I suggest you do a simple lit search on 'junkDNA'...

[St4791]

Brilliant people are capable of leading historical paradigm shifts or revisions.

Obviously you are not one of them and that precisely is your problem JohnnyBananas802.

Negative criticism of Pellionisz, will not make you measure up.

Do me a favor and keep you suggestions to yourself.

[doppelganger313]

Your response seems to be a non-sequitur. It does nto appear to an objective reader that Johnny was attempting to set him or herself up as a brilliant paradigm-shifter at all; I do not see how bringing up a legitimate criticism makes you think he/she was. Adoration of Pellionisz, on the other hand, will not erase his tactics.

[Pellionisz]

With the affordable full human DNA sequencing already here (Complete Genomics shown their first full human DNA sequence for $5,000 in the February 5th meeting in Marco Island, FL - and Pacific Biosciences published a "proof of concept" paper in Science for full DNA sequencing in the range of $100 in little over a year from now, we are all heading towards a "Genome Based Economy". The Churchill Club held a Panel on January 22, 2009 with the title "Personal Genome Computing" - search it in YouTube

[darked89]

Waste of time. This guy shitck is to dazzle biologist with comp-math-phis terms (fractal, recurency, FPGA) and comp guy with bio terms (Purkinje cells etc.). It does not work fr a bioinformatician.

I quited soon after statement that without DNA methylation we would have problem with thermodynamics of DNA. Wow, simply wow! So Second law is so specific? Using energy DNA repair is not good enough?

Bombastic names ("circle of life" anyone?), prosecution complex + penchant for kicking corpses.

[darked89]

@33'01''

Slide reads:

"""

As long as DNA>RNA>PROTEIN was a closed system The Second Law of Thermodynamics applied - an increase of enthropy was inevitable

"""

FYO: nobody who is somebody ever said that a cell, DNA, replication, transcription or translation is a closed system, much less so Watson, Crick or Ohno. You need energy (ATP)

to run any of these. Methylation or not it is an OPEN SYSTEM.

[Pellionisz]

My PR warns against anonymous "shitck" name-callers. Great that you second my statement: DNA is an OPEN SYSTEM where genome entropy is not inevitable to escalate. So let's give hope, not a gloomy mindset that we are stuck with genomic glitches! Interdisciplinary scientists note I focused on DNA - not cells. With energy pumped into it, entropy increases - unless DNA is open to changes by epigenomic interference. Molecular biologists will agree that methylation is #1 mechanism in the limelight.

[JohnnyBananas802]

I agree. You should read his forays onto internet discussion boards. He recently claimed, for example, that geneticist T. Ryan Gregory agreed that junkDNA is a myth and referred to one of Gregory's blog posts dated Sept. 18. Well, the title of that blog post did contain the words "junkDNA" and "myth", but he was referring to the claim that there is no such thing as junkDNA is a myth. Pellionisz was unable to understand that, and when corrected, simply ignored the guy that pointed it out..

[WouterVanOoijen]

This sounds good, but once you actually analyse what he says it is often total nonsense. A mix of words from various sciences, used with total disregard for their definitions.

[sntk1]

This is a piece of blithering buffoonery from someone who doesn't begin to understand Pellionisz, much less the import of his ideas.

[Pellionisz]

Thomas Kuhn, in his bestseller book "The Structure of Scientific Revolutions" (1969) said that in a paradigm-shift the old and new definitions are mutually incompatible. Wouter van Ooijen, a young computer scientist, is apparently unaware of the fact that ENCODE (June 14, 2007) called for a "re-thinking of old beliefs" of 100-year old Genetics; including the very definition of what a "Gene" might be. One might recommend viewing a Panel (YouTube "pellionisz") struggling with the same challenge.

[DrugFreedom]

This is an interesting video.

It looks like Terrence McKenna had some promising ideas about genetic evolution after all...

[davidwizard2006]

sarah ann boswell

[madashelldude]

Wow, 18 months?! Finally we'll know the origins and migration paths of all nations, this could be explosive in Eastern Europe. Hungarians tried to find their ancestral home for centuries. This will become political very fast.