ThomasConena

[amontazer]

ANATOMY HERE I COME WOOOOOOOOOOOOOO

[marnixzio]

use smartscreen dumbass

[hoylematt1]

Yeah there is some wrong information here. The primary concentration of urine occurs at the medullary collecting ducts, NOT the thick ascending loop of henle.

[08chrisandbec]

1:36 bawl of yaaan LOL...Great video

[mydas1]

The purpose of the loop of Henle is to create the high osmotic gradient in the medulla. Also, the purpose of the ascending limb being impermeable to water is to prevent water escaping with the sodium ions that are being reabsorbed.

[MWMburton]

Protiens do not enter the glomerulus unless the glomerulus is damaged.

[TheLaydeeNaee]

@MWMburton however small proteins do, which is then broken down into amino acids which diffuse into blood

[gunjan0808]

thanks. that helped a lot! but during the vid. a silly question striked my mind. why is the loop of henle a U shaped structure? it could be a coiled structure which would result in greater surface area. but anyways, thanks :)

[halmarilynsessions]

This is a vigorous but wrong explanation. The comments below are all correct. It is a great explanation of everything but the counter current mechanism. Also: protein does NOT filterat the glomerulus, unless you have glomerulonephritis, The osmolarity drops as you go back up the loop (in the tubule) 

[imaballababy]

Whatever dada said is correct. The teacher here only got part of the mechanism right. Also he didnt explain how the Countercurrent mech. is built up

[kriola08]

=D Yay! This was very helpful, thanks!

[thestaceymarsh]

protien is not filtered out at the glomerulus

[peikarm]

Thank you for the direct style! Mucho helpful

[eriboyish]

the world needs people like thank u very much

[bitaalfool]

there are more information neglected

[justnichols]

I like your teaching style.

[Versa091]

uh, first like dada said- your explanation is wrong. secondly we do not call the fluid urine till it leaves the duct, it is tubular fluid since a good amount is still absorbed back. just saying...

[dada42277]

I believe there is a mistake in this explanation of the countercurrent multiplier system. Due to the active transport of NaCl from the ascending limb of the Loop of Henle, the urine will actually become LESS concentrated as it ascends. It is in the medullary collecting ducts that the ultimate concentration of urine occurs (driven by water flowing out of the tubular lumen to the hyperosmolar interstitial fluid.

[AJRQuincy]

Thanks :)

[hanasia2011]

just check videos about this urine concentration provided by dr.najeeb beleive me after you listen to his lectures then you can not listen to any of other lectures provided by other "good" teachers.just try it.i am just a med student and so happy for learning from dr.najeebs videos.i am SURE YOU WILL ENJOY IT ALOT AND YOU WILL BE thankful that someone like me shared it with you! it is up to you\! btw.6:33 urine doe NOT REMAIN CONCENTRATED.THNAKS!

[kmrnzhr]

No mention of inorganic ions, the loop of henle has these ions moving out in the ascending limb, and in the collecting duct water moves out by osmosis as the water potential in the medulla is very low.

[habichuelablanca]

Was very helpful :-)

[buckle24x]

have my anatomy final tonight and this video was loads of help. thanks.

[DownWithForever]

thanks

[Turtle72407]

Great mini lecture! Thank you so much! =)

[ashmortazavi]

perfect explanation 

[Benz1o]

awesome explanation, really helped me understand the material!

Thank you!!

[blkrose80]

thank you only video i found that explained this clearly

[pierrefection80]

thank you very much...that was very interesting

[JonMoore19]

1st year med student.

Thanks for making this understandable.

[minerslave4]

hey guys i'm in bio 101 and I got confused by the vague description written by my textbook explaining the functions of the nephron. Some important stuff they left out is the fact that the 'salt water bath' also has the peritubular capillaries collecting the water instead of just diffusing into the interstitial fluid and somehow getting picked up (part that confused me picture only shows interstitial fluid, no capillaries surrouding loop or neprhon). What level course do we learn this at? curious

[timothyj]

thanks for this.

[ma4eusz]

At 6:36 there is a little mistake or a mental shortcut.

I guess. Fluid in distal tubule is HYPOTONIC. Urin becomes concentrated later in collecting duct thanks to manufactured (by loop of Henle) hypertonic interstitial fluid.

Isn't it?

[phulei]

@ma4eusz Yes that is true.

[wilsoncormack]

@ma4eusz I think so

[kubu79]

enough banal of a dissertation. I want my 9.36 minutes back!

[phulei]

Protein filtrated? That can't be correct. The pores of the fenestrated capillaries are too small for protein to go through. And, the basement membrane of the capillaries is negatively charged which will also repel the protein.

[wilsoncormack]

@phulei albumin is negatively charged. bigger proteins can't pass through the basement membrane, capillary endothelium and podocytes, but small amino acids can.

I just looked it up on Guyton cuz my finals is in a few days

[7dmatto]

Great video! Thanks!

[Gina84768]

I disagree with the people who are saying this is inaccurate. I have a current textbook - released 2009 and his explanation matches the textbook - only he is easier to understand. He doesn't go into the vasa recta and their role in the countercurrent mechanism, but then this is only about the multiplier portion of the mechanism.

[Wonderfully90]

great vid!

[MissLadle]

ojoreakatheoj is right. This video is inaccurate and unhelpful. It certainly does not present current knowledge as presented in standard texts.

As a presenter he is really quite convincing. It's a pity he is talking nonsense.

Unless, forgive the pun, he's taking the p*ss. :P

[ojoreakatheoj]

Are you sure this is accurate? I've come across competing description of the functions of the Loop of Henle.

In this vid, the Loop serves to concentrate the Urine. However, sources in my undergraduate coursework have contended that the loop serves only to establish the high osmotic concentration in the renal medulla, but it leaves the Loop hypotonic to the interstitium. The loop of henle, then, only serves to concentrate the medulla, and then the collecting duct concentrates the urine.

[ghaithnajah]

.and that is why i case of ADH deficiency (which act on collecting duct) the urine is diluted . BUT the high osmotic concentration in the renal medulla will cause the water to move from the descending loop of Henley so that will decrease the water excretion another point the urine in the asending loop is more diluted and not concentrated as he mentioned .

[obada555]

that was very helpful.. thanks a lot :D

[jekissarae]

Thanks for making this subject easy to understand.

[moelatte80]

This was very informational and very well made. I really appreciate your effort in demystifying this important topic. I look forward to seeing more videos from you.

[rajpat43]

Thanks it really helped a lot. Wish every teacher should so this for every lecture. Thanks again :)

[kubu79]

the countercurrent multiplier mechanism was not explained into much detail. But thank you anyway. Great lecturer.

[7dmatto]

great video! thanks!

[viengneesee]

thank you !!  : D

[mjagdmann]

thanks!