Britain's educational research is still the best in the world because their scientists are more like philanthropist in regards to their discoveries. Great job Dr Aboobaker and your colleagues.
You look slightly heavier now professor. Sorry, but it's true. Lay off the chips maybe.
thanks I'll bare this in mind... although the aesthetics of how I look has very little to with the science. I am not trying sell aftershave, rayor blades or soft drinks. Plenty of other places you can do look for that.
@AzizAboobaker My mum and dad got diabetes and high blood pressure and they are also academicians. It's not about looks sir. Sorry if I struck a nerve.
@MeDanone Being healthy is nice, and good. Telling someone that you're sorry but you think they should lay off the chips is juvenile.
If you want to make a difference in someones health, please do so. I would simply like to point out that your method is negative and will only attract negativity, and also that YouTube is probably not a good platform for you.
Someone's a little sensitive. Oh come on Ibogaine306. You know I didn't mean anything horrid. Come on. Laugh for me. Professor Aboobaker is probably laughing as well.
Please excuse my ignorance but it isn't clear to me. Is this the gene for how to make a head, like even from birth (or whatever worms do) or is it only responsible for regenerating heads? Or is that even a valid question :)
@chrisofnottingham I think the gene expresses a certain protein that drives the cellular division of brain cells in a certain area. When the protein is found is where the structure of the brain is found and where is isn't thats where the structure isn't found. When the gene is knocked out ie removed, the stem cells had not genetic marker to where they should make brain hence no brain is present. I think thats how it works.. I'm not sure....
@silentelysium So it doesn't really sound like it's responsible for actual regeneration, more like what to put there. Then again, I suppose that is part of regeneration. This is what happens when one starts asking questions about a subject with zero initial knowledge :)
QUESTION: At what age or stage in their lifecycle, can the worm no longer regenerate? Is the regenerated part "younger" than the rest of the worm i.e. could it survive longer? Does the older part die off first?
The animals constantly replace all there cells even when they are intact, so in a sense all the differentiated cells have finite lifespan. The adult stem cells of the asexual though may effectively be immortal.... we aren't sure yet.
This sounds like a good premise for a science fiction / horror movie. Imagine facing an enemy that you must to destroy in its entirety or else it will regenerate and even create more copies of itself.
@qx773 Yep, it's why we have to be careful about what we do with this information. Sci-fi is quickly becoming reality and governments are going to eat this stuff up for military purposes unless it is controlled. (This is of course If and When it becomes possible to manipulate this gene in humans or other complex organisms.
Great research and congrats on the paper. I remember after chopping these things up in high school Biology class and then going out to some ponds to find some I could bring home. I was amazed to see the little pieces could still crawl around after being unmercifully hacked up into little pieces. Thanks for posting the video.
@Cusk0 I'd assume so since they only regenerate after being dissected, not regenerating as they go along. Their bodies would stop producing so many cells as they get older - just like us.
@Cusk0 Good question. I would imagine that the telomeres are still degraded as the genes divide but do the worms have the ability to repair them, starting fresh as it were, when cut into pieces? If not, you would have some worms starting out very "old".
Wait.. Are you telling me you're about to discover how to gene manipulate anything to be immortal? Do you know what this means!? That would be the most important find in the history of biology! ADAM is just about to become real. Immortal sea slugs...
So What Happens If You Eat Alot Of Them Then Say You Chopped Off Your Finger Would It Grow Back? No serious would it?
Or would your body treat it as a parasite and being a perasite I>E a worm would it just live on and on like tape worms sometime do and are they related?,
Also is it Asexual and if so is it the same worm or a 4G clone
@1greentoad You'd digest the worm, when you eat things you don't absorb the physical/genetics of it (ie meat), you just take whatever nutrients you body can gain from it.
We surely need to develop some 'Neurons regeneration' techniques....otherwise immortality is impossible!! Neurons are the most important cells in the body, because they harbour consciousness, emotions and everything.
We surely need to develop some 'Tissue regeneration" techniques, otherwise immortality is impossible!! Tissues are the most important cells in the body, because they form the heart, brain, lungs...
@123IOWNALL321 Basically we are talking about the same thing. 'Tissues' are just bigger conglomerations of 'cells'. My point was that the brain is the most important because it retains all the memories and consciousness. There's even a seperate cryogenic technique for cryopreserving 'brains' only, instead of full bodies.
Not really. My point is, what significance does the brain have when you have no heart or lungs? Or eyes? Ears? There's no single most important part of the body as far as regeneration goes. You can't live without a heart or lungs, which is the basis of this argument (which part of the body inhibits immortality?). What the brain does besides keep us alive is irrelevant in this case.
@123IOWNALL321 OK. My point is that brain is the most important thing because it it's an irreplacable part of one person's identity. You can virtually have everything transplanted with mechanical parts (prosthetic heart etc. ) and still be YOURSELF. So, the only chance for spiritual immortality (I mean keeping one's mind as it is), would be regenerating parts of our own 10 ^ 11 Neurons. Everything alse , in an emergency, could be can be replaced with transplants (mechanical and or/biological)
What I'm saying is if you DIDN'T have that body part; artificially making it so you DO have that body part is kind of cheating around that. I think you got what I meant though, and I get what you mean, but in terms of keeping your body functioning and alive, there are multiple organ systems that do that.
@123IOWNALL321 "there are multiple organ systems that do that." Ok i agree with your point about the need of multiple organs to keep the whole body alive. But it's not enough to have the body 'Alive', if we cannot regenerate neurons. The brain is the most important part in the whole sense of one's 'SELF' and 'ID'. So regenerating stem cell research is vital to focus primarily on regenereting neurons, instead of other various types of cells. That's what i meant.
If you cut a certain part, it can't regenerate and die. We tried this in bio, they were gestating and died because they didn't had enough energy to regen.
Would it be possible to give a human this gene, in order to give said human the ability to grow a new head? Or would it be entirely impossible, in part due to lack of stem cells?
@Chobonaru As he explains in the video, humans have at least a similar gene (3:11), but it's not as effective because of the smaller percentage of stem cells (0:50).
@Chobonaru He said in the video that all humans have the gene and it is likely needed for brain formation. I don't know whether I'd want to regrow a head - it'd be like a baby brain in an adult's body. It'd be neat if they found a way to regrow fingers or even a limb. To cure arthritis, remove the hand and let a fresh one grow back!
@Chobonaru As I understand it, it's just the gene that instructs where to grow the head basically, not the how. Our gene is fairly similar and it works quite like the worm's does, but our head can only form once so the instructions on where to grow the head won't be needed a second time.
There are a lot of genes that tell where different parts need to grow in development. Some of these can be moved from one species to another and no harm is done if those genes have stayed similar enough.
Great piece of work and nice presentation .. I think my smed-prep gene has some methyl groups nearby ..
Coastlinewalks 2 months ago
This is amazing.... did anyone else see that blue sprite bottle in the background? I MUST TELL THE WORLD!!!
iamsobanned 2 months ago
Sharing this one on FB. This is great. Thanks.
aardwolf71 9 months ago
looking forward to your further research..
furbypaper 9 months ago
then stem cells could be the key to immortality
legend956 10 months ago 2
interesting video. I wonder which gene tells the stem cells that it should grow a head, and not a tail. Pardon me. I am a novice.
Prof. OOm
OOmdebah 1 year ago
....someone looks sleep-deprived
coolragazzo94 1 year ago
0:00
WesArts 1 year ago
amazing
gman9884 1 year ago
Great but out of sync. :)
Badgerinthenight 1 year ago
So if i take my brain off i would just grow a new one if i had lots of stem cell and the gene
Deady4u 1 year ago
Britain's educational research is still the best in the world because their scientists are more like philanthropist in regards to their discoveries. Great job Dr Aboobaker and your colleagues.
You look slightly heavier now professor. Sorry, but it's true. Lay off the chips maybe.
MeDanone 1 year ago
@MeDanone
thanks I'll bare this in mind... although the aesthetics of how I look has very little to with the science. I am not trying sell aftershave, rayor blades or soft drinks. Plenty of other places you can do look for that.
AzizAboobaker 1 year ago
@AzizAboobaker My mum and dad got diabetes and high blood pressure and they are also academicians. It's not about looks sir. Sorry if I struck a nerve.
MeDanone 1 year ago
@MeDanone Being healthy is nice, and good. Telling someone that you're sorry but you think they should lay off the chips is juvenile.
If you want to make a difference in someones health, please do so. I would simply like to point out that your method is negative and will only attract negativity, and also that YouTube is probably not a good platform for you.
And by chips, do you limeys mean french fries?
Ibogaine306 1 year ago
@Ibogaine306
Someone's a little sensitive. Oh come on Ibogaine306. You know I didn't mean anything horrid. Come on. Laugh for me. Professor Aboobaker is probably laughing as well.
MeDanone 1 year ago
Please excuse my ignorance but it isn't clear to me. Is this the gene for how to make a head, like even from birth (or whatever worms do) or is it only responsible for regenerating heads? Or is that even a valid question :)
chrisofnottingham 1 year ago
@chrisofnottingham I think the gene expresses a certain protein that drives the cellular division of brain cells in a certain area. When the protein is found is where the structure of the brain is found and where is isn't thats where the structure isn't found. When the gene is knocked out ie removed, the stem cells had not genetic marker to where they should make brain hence no brain is present. I think thats how it works.. I'm not sure....
silentelysium 1 year ago
@silentelysium So it doesn't really sound like it's responsible for actual regeneration, more like what to put there. Then again, I suppose that is part of regeneration. This is what happens when one starts asking questions about a subject with zero initial knowledge :)
chrisofnottingham 1 year ago
Great video! Wanted: more Biology clips from Nottingham's research!
plagutus 1 year ago
QUESTION: At what age or stage in their lifecycle, can the worm no longer regenerate? Is the regenerated part "younger" than the rest of the worm i.e. could it survive longer? Does the older part die off first?
Thank you.
DrBones666 1 year ago
@DrBones666
The animals constantly replace all there cells even when they are intact, so in a sense all the differentiated cells have finite lifespan. The adult stem cells of the asexual though may effectively be immortal.... we aren't sure yet.
AzizAboobaker 1 year ago
Great research, I'm certainly excited about it. Can't wait to see what you find out next!
DanMan7997 1 year ago
congrats!!!!!!!!!
crisanbe 1 year ago
Amazing stuff, thank you for sharing with us.
Atheistprimate 1 year ago
When will you start to put the gene in humans? =D
P.S. blue sprite?
AgentDexter47 1 year ago
incrediblev!
cool stuff.
thanks for sharing your knowledge.
fstroch999 1 year ago
if i eat alot of those worms will it make me immortal?
AdzNaz 1 year ago
@AdzNaz
No, but it might make you feel sick....
AzizAboobaker 1 year ago
This sounds like a good premise for a science fiction / horror movie. Imagine facing an enemy that you must to destroy in its entirety or else it will regenerate and even create more copies of itself.
qx773 1 year ago
@qx773 Yep, it's why we have to be careful about what we do with this information. Sci-fi is quickly becoming reality and governments are going to eat this stuff up for military purposes unless it is controlled. (This is of course If and When it becomes possible to manipulate this gene in humans or other complex organisms.
Sturrmm 1 year ago
"make research public" i like the sound of that
ammanRex 1 year ago
Ill keep this worm in mind when im making my death monster.
IMakeOrWatchVideos 1 year ago 2
if you loose and grow another brain you will forget everything you new im gessing... =/
shadowace421 1 year ago
genetic engineering is so cool, but a little bit scary
mvszao 1 year ago
mkay ^^ awesome video!
Patrickssj6 1 year ago
I'm waiting for the tabloids to say you're growing brains for a supercomputer.
Nice work, it's great that you got encouraging results.
P00P0STER0US 1 year ago
Cool! One day maybe we'll be able to use techniques based on this discovery to help politicians regenerate their brains! :D
BeanTVYWG 1 year ago
Great research and congrats on the paper. I remember after chopping these things up in high school Biology class and then going out to some ponds to find some I could bring home. I was amazed to see the little pieces could still crawl around after being unmercifully hacked up into little pieces. Thanks for posting the video.
fbt2007 1 year ago
zombies people should die u live u die the end
godsend420 1 year ago
Do these worms die of old age though?
Cusk0 1 year ago
@Cusk0 I'd assume so since they only regenerate after being dissected, not regenerating as they go along. Their bodies would stop producing so many cells as they get older - just like us.
angelxsid 1 year ago
@Cusk0 Good question. I would imagine that the telomeres are still degraded as the genes divide but do the worms have the ability to repair them, starting fresh as it were, when cut into pieces? If not, you would have some worms starting out very "old".
fbt2007 1 year ago
Wait.. Are you telling me you're about to discover how to gene manipulate anything to be immortal? Do you know what this means!? That would be the most important find in the history of biology! ADAM is just about to become real. Immortal sea slugs...
Akhiloth 1 year ago 2
@Akhiloth
NO DEFFINITELY NOIT SAYING THAT....
AzizAboobaker 1 year ago
This is the Wolverine of worms.
culwin 1 year ago
Make super smart fruit flies with giant regenerating heads
Craydon 1 year ago
More proof we should put more research into stem cells...
StaupEimer 1 year ago 2
Cool
tk0145 1 year ago
So What Happens If You Eat Alot Of Them Then Say You Chopped Off Your Finger Would It Grow Back? No serious would it?
Or would your body treat it as a parasite and being a perasite I>E a worm would it just live on and on like tape worms sometime do and are they related?,
Also is it Asexual and if so is it the same worm or a 4G clone
Just Asking...
1greentoad 1 year ago
@1greentoad You'd digest the worm, when you eat things you don't absorb the physical/genetics of it (ie meat), you just take whatever nutrients you body can gain from it.
angelxsid 1 year ago
Wow, interesting!
metamorphises 1 year ago
ha ba ba u ba ba mao ba ba u ba ba mao... do you know that gene is the worm?
EnavSounds 1 year ago
OMFG THAT'S SO COOL..
ihatedisney666 1 year ago
We surely need to develop some 'Neurons regeneration' techniques....otherwise immortality is impossible!! Neurons are the most important cells in the body, because they harbour consciousness, emotions and everything.
Neueregel 1 year ago
@Neueregel
We surely need to develop some 'Tissue regeneration" techniques, otherwise immortality is impossible!! Tissues are the most important cells in the body, because they form the heart, brain, lungs...
123IOWNALL321 1 year ago
Comment removed
Neueregel 1 year ago
This has been flagged as spam show
@123IOWNALL321 Basically we are talking about the same thing. 'Tissues' are just bigger conglomerations of 'cells'. My point was that the brain is the most important because it retains all the memories and consciousness. There's even a seperate cryogenic technique for cryopreserving 'brains' only, instead of full bodies.
Neueregel 1 year ago
@Neueregel
Not really. My point is, what significance does the brain have when you have no heart or lungs? Or eyes? Ears? There's no single most important part of the body as far as regeneration goes. You can't live without a heart or lungs, which is the basis of this argument (which part of the body inhibits immortality?). What the brain does besides keep us alive is irrelevant in this case.
123IOWNALL321 1 year ago
@123IOWNALL321 OK. My point is that brain is the most important thing because it it's an irreplacable part of one person's identity. You can virtually have everything transplanted with mechanical parts (prosthetic heart etc. ) and still be YOURSELF. So, the only chance for spiritual immortality (I mean keeping one's mind as it is), would be regenerating parts of our own 10 ^ 11 Neurons. Everything alse , in an emergency, could be can be replaced with transplants (mechanical and or/biological)
Neueregel 1 year ago
@Neueregel
What I'm saying is if you DIDN'T have that body part; artificially making it so you DO have that body part is kind of cheating around that. I think you got what I meant though, and I get what you mean, but in terms of keeping your body functioning and alive, there are multiple organ systems that do that.
123IOWNALL321 1 year ago
@123IOWNALL321 "there are multiple organ systems that do that." Ok i agree with your point about the need of multiple organs to keep the whole body alive. But it's not enough to have the body 'Alive', if we cannot regenerate neurons. The brain is the most important part in the whole sense of one's 'SELF' and 'ID'. So regenerating stem cell research is vital to focus primarily on regenereting neurons, instead of other various types of cells. That's what i meant.
Neueregel 1 year ago
what would you get if you slice it laterally?
ProtectTheDamned 1 year ago 39
@ProtectTheDamned dead worm
mike809453908 1 year ago
@ProtectTheDamned
the worms regenerate the missing half just fine
AzizAboobaker 1 year ago
If you cut a certain part, it can't regenerate and die. We tried this in bio, they were gestating and died because they didn't had enough energy to regen.
kingpopaul 1 year ago
How old do these flat worms live via old age?
onthecuttingedge2005 1 year ago
I could do with growing a new brain ,if you guys need a guinea pig
sausage4mash 1 year ago 31
Would it be possible to give a human this gene, in order to give said human the ability to grow a new head? Or would it be entirely impossible, in part due to lack of stem cells?
Chobonaru 1 year ago
@Chobonaru O_O
Techn0Junki3 1 year ago
@Chobonaru As he explains in the video, humans have at least a similar gene (3:11), but it's not as effective because of the smaller percentage of stem cells (0:50).
gwaur 1 year ago
@Chobonaru He said in the video that all humans have the gene and it is likely needed for brain formation. I don't know whether I'd want to regrow a head - it'd be like a baby brain in an adult's body. It'd be neat if they found a way to regrow fingers or even a limb. To cure arthritis, remove the hand and let a fresh one grow back!
reevesAstronomy 1 year ago
@Chobonaru As I understand it, it's just the gene that instructs where to grow the head basically, not the how. Our gene is fairly similar and it works quite like the worm's does, but our head can only form once so the instructions on where to grow the head won't be needed a second time.
There are a lot of genes that tell where different parts need to grow in development. Some of these can be moved from one species to another and no harm is done if those genes have stayed similar enough.
Itslvle 1 year ago