Sorry I didn't see your message earlier. So as noted below, while high volume will decrease renin secretion indirectly by increased stretch, B1 leads directly to renin secretion.
From Harrison's Internal Medicine, 17th edition, Chapter 241 Hypertensive Vascular Disease, subsection Renin-Angiotensin-Aldosterone (Page 1551) it states: "There are three primary stimuli for renin secretion: (1) decreased NaCl in the thick ascending limb of the loop of Henle (macula densa mechanism), (2) decreased pressure or stretch within the renal afferent arteriole (baroreceptor mechanism), and (3) sympathetic nervous system stimulation of renin-secreting cells via B1 adrenoreceptors."
Great video, but just to correct a little mistake. Beta 1 receptors do not INCREASE renin secretion by the kidneys, they actually DECREASE it, this is because B1 receptors exert positive chronotropic and inotropic effects on the heart thereby causing high volume states (renin secretion is favored by a low volume state).
@iagaku you might wanna double check that B1 receptors DO increase renin release (Sympathetic nervous system activity, which also controls blood pressure, acting through the beta1 adrenergic receptors).
Take your pants off too?
BroadrickA 2 weeks ago
Alpha1 --> Dcreases RENIN
B1 --> Increases RENIN
Alpha2 --> Decreases INSULIN release
B2 --> Increases INSULIN release
alifeili 1 month ago
Sorry I didn't see your message earlier. So as noted below, while high volume will decrease renin secretion indirectly by increased stretch, B1 leads directly to renin secretion.
pictorialmnemonics 11 months ago
From Harrison's Internal Medicine, 17th edition, Chapter 241 Hypertensive Vascular Disease, subsection Renin-Angiotensin-Aldosterone (Page 1551) it states: "There are three primary stimuli for renin secretion: (1) decreased NaCl in the thick ascending limb of the loop of Henle (macula densa mechanism), (2) decreased pressure or stretch within the renal afferent arteriole (baroreceptor mechanism), and (3) sympathetic nervous system stimulation of renin-secreting cells via B1 adrenoreceptors."
pictorialmnemonics 11 months ago
Great video, but just to correct a little mistake. Beta 1 receptors do not INCREASE renin secretion by the kidneys, they actually DECREASE it, this is because B1 receptors exert positive chronotropic and inotropic effects on the heart thereby causing high volume states (renin secretion is favored by a low volume state).
Great video anyway.
iagaku 1 year ago
@iagaku you might wanna double check that B1 receptors DO increase renin release (Sympathetic nervous system activity, which also controls blood pressure, acting through the beta1 adrenergic receptors).
nazmus 1 year ago
that is so cool !! thanks ..U made it v.easy to remember ..
DrDanya09 1 year ago
hahaha i love thissss!!!!!!
likefirebird 1 year ago