DNA Transcription (Advanced)

[xxTaKe2xx]

advanced = baisc + one second :D

[D33SS3]

Thats not advanced at all

[DrFritz714]

Good animation

[chrispikeyp]

i enjoyed this vid

[phuturephunk]

I've watched both the simple and advanced versions of this and the only question I have is: How does it know when to stop transcribing?

[Arm0ry]

@phuturephunk Just like promoters, there are also "Stop" regions where other factors can bind to the DNA. When the RNA polymerase encounters those factors, it stops.

[D33SS3]

@phuturephunk Rat1 recruted by the CTD tail

[DrFritz714]

@phuturephunk RNA Pol eventually reaches something called a DNA terminator sequence (TAC), once it transcribes this region a specific protein (called Rho) or it can terminate by the RNA forming a hairpin loop on complimentary bases transcribed)

[lollipopswirl123]

i'm confused about what helicase, DNA polymerase, and RNA polymerase does. help pleasee?

[DrFritz714]

@lollipopswirl123 DNA polymerase and helicase are both enzymes that are onyl associated with DNA replication where as RNA polymerase is only associated with transcription. (RNA polymerase has elements within its structure that are similar to helicase but not the same)

[saguhh00]

DNA transcription is against TEH BABBLE!!

[dhkahat]

this is a FANTASTIC animation! one little correction: the RNA polymerase doesn't move along the double helix. the double helix is shuttled through the RNA polymerase. basically the enzyme is static while the DNA is moving.

[PauleePessimist]

1:09 CONTACT!!

[blackphosphor]

amazing! taking microbiology right now and this definitely helps.

[Randomizer77]

And this happens WHERE? in our BODIES? wow 0.0

[Rao665]

@DeathIzurfriend

ZzzZzzZzzzzZzzzzzzzZzzz boooooooriiiiinngg....

De-FENSE! Wooo Wooo De-FENSE! WOoo Wooo

[JamieGorzynski]

they look like tangfastics :P



[JamieGorzynski]

they look like tangfastics :P

[felixthemaster1]

our bio teacher talked a lot bout this.

[DTrinh09]

Subunits go in. RNA comes out. Never a miscommunication. You can't explain that!

[sinachiniforoosh]

@DTrinh09 explanation:chemistry.

[xyzjoanna]

How does the activator protein come in contact with the initiation complex if the enhancer region to which the protein binds can be thousand of base pairs away? Is the activator protein just really large?

[IkonPhenom]

@xyzjoanna

The DNA is bended by DNA-bending proteins and it's this bending which puts the activators, already attached to the enhancers, in contact with mediator proteins (recruited by the activators, themselves). The mediator proteins attach to transcription factors. All these form the transcription initiation complex

[JeremiasMezenga]

Why she stopped? Have stop codons, but why?

[DavidEdwardSchnell]

SHAKIRA SINGS "THIS TIME FOR AFRICA" AT THE WORLD CUP! ARISE! ARISE! ARISE! [evil cackle]

[killaonmoco]

When the zipper made contact with the activators that little thing just took off and I could imagine it going "WEEEEeeeeeeI'mcopying!" lol.

[TheMordyS]

@killaonmoco and the litlle piggy went WWEEEEEEEEEEEEEEEEEE

[TrueMusou]

Wow that was one of the most dynamic animations I've seen of transcription

[SVercelli]

This is quite good. One of the better videos for a HL IB Biology student. All the other ones are too simplified

[booster079]

The TFs and TF11D, TF11B, TF11F and TF11E/H. RNA polymerase doesn't move, its immobilised within the nucleus in transcription factories and the DNA is brought to the polymerases, otherwise surely the RNA transcript would get tangled in the DNA. That's what I think anyway.

[IloveYOUviruses]

@booster079 they move as you breath dummy

[reptilianshifter]

Psychedelic

[caljr86]

Could somebody please indentify the transcription factors? I think that the first one is TF2D and TF2B. The second, wich comes with the polymerase can be the TF2F. The other ones ares TF2E and TF2H. Am I right?

[M1K33yBoy]

this is so damn cool !! Like real sci-fi :) damn I've become a mathematician

[Elisheval]

im confused--- is this RNA polymerase or DNA polymerase???

[RoseSheeps]

Now working on mine too... sorry for bothering/timewasting

[DNALearningCenter]

@RoseSheeps You're not timewasting at all; we appreciate you letting us know if there is a problem! ;)

[RoseSheeps]

Looks great, but I can only access the first half - it cuts out at 0:45.

Is it broken? or is it just my computer?

[DNALearningCenter]

@RoseSheeps I just watched the video the whole way through with no errors; it sounds like a problem on your end unfortunately.

[meme2342]

Really nice animation - I have a much better understanding of distant gene enhancers now!  Thanks

[uniterscron]

Where is the CTD of RNApol?