Neuroanatomy - CSF Flow

[art4med]

This well-known diagram is by Frank Netter MD!

[tberkel2]

a minute to explain that this is cut in half?

[AlexHop1]

Thanks very much. Very explanatory!

[desolationdesigner]

I was diagnosed with intracranial hypotension a couple days ago. I want to know as much as possible about it before I start treatment. Are there any statistics comparing csf levels and effectiveness of treatment in relation to the amount of pressure recorded at first lumbar puncture.

[ratuscafermecata]

thank you!!! neurophysiology exam tomorrow and my textbook is useless when it comes to explaining CSF flow. awesome video.

[qrais]

so tela choroidea contains pia matter surrounded by ependyma, and its irregular edge is called choroid plexus which produces CSF. CSF in the posterior (occipital) horn of the lateral ventrice is quite interesting because hippocampus is forming medial half of the floor of occipital horn of lateral ventrice - and the ventricular surface is surrounded by a thin sheet of white matter. Is all of the borders of the ventricular cavity surrounded by this thin sheet of white matter? - 1.year med student

[drlipon]

until it equals the effective filtration pressure...when it counter balance and stop further production of fluid....but that is far enough pressure to cause harm for to the brain and brain tissue degenerates and shrinks and the high pressure space dilates to cause slow and progressive damage to brain tissue...for newborn babies whose skull is not rigid it also start getting bigger to accommodate that increased volume and gives rise to a condition called Hydrocephalus....Thank you....

[drlipon]

the fluid...but in csf its a different reason what cause the pressure gradient....there are places where fluid is being produce that added fluid increasing the pressure...and there are places where csf being absorbed that removal of fluid is creating a sucking action or negative pressure thus there is a pressure gradient and fluid flows from high pressure to low pressure area by default...if there is any blockage on the path way then pressure keeps rising in that isolated part...

[drlipon]

this video is the best description and explanation csf production and circulation among those i looked....for the mechanism of circulation of csf or the factors that affect ICP i want to add this....as for any circulatory system there is always a pressure gradient and fluid circulates from high pressure area to low pressure area..as of our blood circulation where the mean arterial pressure is 98 mm Hg and the rigt atrial pressure is virtually 0 ..so the pressure gradient is 98-0= 98 which drives

[SILVERHORSE347]

THANKS

[abobatti]

Thank you so much,.

really you helped me!

[ainehannity]

thank you! brilliant explaining, very helpful!! 

[lonewatchman]

The single most exhaustive explanation of a commonly understood rendering for anatomical study.

[MrDrBulla]

Great job mate :-)

[wedwed1984]

Great video

[AndrewG2013]

Thank you so much! I had to watch it multiple times to understand it, the arachnoid granulations is where I got stuck but I think I have it now.

Also, could the sinuses you were talking about...Are they also known as the dural venous sinuses?

Thanks again!

[MrDrBulla]

@AndrewG2013 Dural venous sinuses is the umbrella term for the ..... dural venous sinuses (superior & inferior sagittal sinus, transverse, straight, superior and inferior petrosal etc....

[AndrewKFletcher]

What is the driving Mechanism? We know the heart is not involved and that respiration and posture are involved so what is the driving force that causes the csf to circulate?

[MrDrBulla]

@AndrewKFletcher CSF is driven by intraventricular pressure (the pressure inside the ventricles) which is higher than that in the dural venous sinuses (DVS) so CSF passively diffuses across through the arachnoid granulations and into the DVS's. I read somewhere as well they think there may be an active process involved with it, but it definately has a passive process about it.

[AndrewKFletcher]

@MrDrBulla Increasing or decreasing the pressure in the dural venous sinuses would not cause the csf to circulate, it would as you say afford passive diffusion, although I suspect that the pressures inside the internal jugular veins caused by tension in the blood inside the veins provides us with active transport of csf into the venous return. Posture can be shown to alter the pressure and tension in veins.

[MrDrBulla]

@AndrewKFletcher Nah the pressure in the DVS's stays the same as they're veins, the pressure inside the ventricles (intraventricular pressure) would exert an effect on the flow of CSF. Pressure in the ventricular system does increase when you stand up ... it almost double from supine (lying down) i think.

[AndrewKFletcher]

@MrDrBulla This is precisely my point, posture alters the pressure inside the veins. Varicose veins for example can be corrected using an inclined bed tilted to five degrees, sloping down from head to toe. This can only be achieved by altering the tension in the blood and reducing the pressure. Both of which will have a knock on affect on cerebrospinal fluid circulation movement into the veins.

[MrDrBulla]

@AndrewKFletcher Wouldn't sloping the bed from head to toes cause pooling of fluid in distal extremeties secondary to an increased central venous pressure? Since blood is under a higher pressure to return to the heart and during sleep we would not use the muscle pump as much, but really only the respiratory pump to aid venous return. This would cause a reduced CSF resorption as the pressure difference b/n the ventricles and DVS's is lower, such that there is more pressure in the DVS's.....

[AndrewKFletcher]

@AndrewKFletcher Quite the contrary, oedema in most cases rapidly resolves when sleeping on an inclined bed. This again supports the change in pressure inside the veins causing the fluids to move from a high pressure area into a lower pressure area. Circulation improves significantly too and yet the heart rate decreases by 10-12 beats per minute and respiration by 4-5 breaths per minute

[scuzzulus]

@MrDrBulla there are ependymal cells lining the ventricles with cilia attached that beat back and forth, pushing the CSF on its way. at least, thats the explanation i`m most familiar with, correct me if i`m wrong.. i`m not sure about the intraventricular pressure, never heard that.

i found this: ``The driving force of the cerebrospinal fluid is modeled through pulsating choroid plexus.`` so it may be a combination of the heart`s beating and the ependymal cells? dunno lol

[AmericanTrekker]

@scuzzulus ependymal cilia are microscopic structures neither sufficient nor necessary to "push" CSF around, though that's a reasonable guess in the absence of further information. If you'd like to see a better use for those cilia see lightDOTsimanonokDOTcom

[smellycheese87]

Amazing! Can you be my neuroanatomy professor ??? lol

[restlessday]

thk u, really helpful! :)

[johntkucz]

Excellent. Very technical.  I appreciate the high degree of technicality and usage of the appropriate medical-neuro-anatomical jargon. great!

[ugadawgs1984]

I appreciate this video...This is a well-done basic functional review of CSF flow and (also vascular drainage) within the brain. This is a good pace for someone reviewing brain anatomy and I like the the tricks to remember the names of the foramina.

[pavlus2]

thank you very very much, this was a great review for me!

[comcv99]

great job!!!!

[kamele08]

wow, thank you...totally helps for my a&p 141 final.

[Yhoah]

awesome explanation! very informative and simple at the same time.

[samimcgee]

thank you so much for this video. I was trying to understand how the csf was produced in the brain it's circulation and it's reabsorption. In order to understand my brother in law's ICP after his hemorrhagic stroke. Thanks again

[F4S4N]

Do more, please ;) This is so awesome!

[sulatorio]

it helps me since i have a report on intraventricular hemorrhage..thank you so much..

[DrHMFIC]

Well done.

[SaraCares]

Very Nice ;-) - Thanks!

[rudabeh]

This is a very useful review for my neuropsych exam. Thanks for posting!

[smolakov]

Thx, it helped!

[tigreletigre]

very helpful!

[superhotgiselle]

thanks i totally needed it.

[gotweakers]

Thank you! This was very educational, especially useful because I have an exam tomorrow :)