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From: TheOnion
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  • what about facebook, that's a fucked up drug 99% of the people "must use". (im 1% - hate the shit)

  • what a bunch of shit, at least they talked about Dune. Spice make you live 300 years yo

  • U4EA is a real drug.4-Methylaminorex

  • Nathan Rabin is such a douche, Dune is Excellent !

  • Wow, how can you not understand that Spice = Oil? It only does "everything" because in the real world, oil does everything in our society. Sheesh.

  • How is dune impossible to follow? You people are retarded. If you can't decipher Lynch (even if he considered the film a failure, it's still a cult classic) then what chance do you have on someone like Joyce or Mann? Art is dead, literature is dead, story telling is dead. Long live the age of the idiots

  • Mugwap Jizz

  • Well, let's see. We've got Jabroka from Alien Nation, (my personal favorite) Venom (Batman,) Red Eye from Cowboy Bebop, various forms of Kryptonite in Smallville, ALZ-112/113 from The Planet of the Apes, the "T" Virus from Resident Evil, Ambrosia/Morpha/Chamalla from Battlestar Galactica, the various "leaves" from The Lord of the Rings, Prozium from Equilibrium, Milk-Plus from A Clockwork Orange, Cordrazine from Star Trek, and the eponymous Formula 51. That's all I can think of right now.

  • Well, let's see. We've got Jabroka from Alien Nation, (my personal favorite) Venom (Batman,) Red Eye from Cowboy Bebop, various forms of Kryptonite in Smallville, ALZ-112/113 from The Planet of the Apes, the "T" Virus from Resident Evil, Ambrosia/Morpha/Chamalla from Battlestar Galactica, the various "leaves" from The Lord of the Rings, Prozium from Equilibrium, Milk-Plus from A Clockwork Orange, Cordrazine from Star Trek, and the eponymous Formula 51. That's all I can think of right now.

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  • Forgot Neuroin from Minority Report. That shit makes you give birth to pre-cognitives.

  • The Spice must flow.

  • "GET OUT OF MY MIIND" :)

  • lol @ the coke being snorted with a 20 euro note...

    with the massive amount of coke being snorted in the U.S they couldnt find a pic with a 50 dollar note and some blow? :)

  • I injected spice into my penus to cure my erectile dysfunction, all it did was make my penus telepaphic-apparantly it doesnt like my ex.

  • No NZT from limitless?

  • What about Adam from Bioshock?

  • Skooma, can ya spare some skooooma?

  • My favourite part of that was the two seconds with Stephen Colbert.

  • but... melange is highly addictive and withdrawal is fatal...

  • You forgot Nuke from Robocop 2

  • SALLY D

  • None of these drugs are as good as Sheen. That shit will give you one hell of a high

  • Although AV Club got a lot of stuff wrong... I really thank them for this episode, because it introduced me to Strangers with Candy. Such a funny show.....

  • Refrain from the anime Code Geass is another fictional drug that makes the people hallucinate about the past.

  • Holy fuck...Did not see that Colbert scene coming!!!!

  • Shit's all about Nuke :D

  • @MatthiusSama Damn skippy, nuke is what got me to try drugs in the first place.

  • i love both dune book and the film!

  • Jerri! Good tiiiiiimes.

  • they forgot nuke from robocop 2

  • Melange makes perfect sense in the Dune books, though

  • What about psycho and jet from fallout?

  • What about Narblast from heavy metal?

  • Stim packs and hab from StarCraft.

  • Give me some soma!

  • @tommysch Soma's not fictional anymore but it was when written by Huxley. Now it's sold under the brand name "Prozac"

  • one word: "Skooma"

  • Also "A Scanner Darkly's" unoriginal Substance D.

  • Dune is a great book, the movie is not so good.

  • "I can kill with a word!" omg lol xD

  • Apparently these boys haven't seen Limitless

  • Dune is great movie!

  • I cant get enough of Kyle. He's so CUTE!

  • Bliss from Captain Planet was my fave..

  • Valkyr in Max Payne - awful.

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  • What about Venom and Titan from the batman series? Or how about that crap in Spider-Man 2099???

  • how about some of the stuff they give Alex in A Clockwork Orange for the Ludovico treatment to work?

  • what about spice from mass effect?

  • Did they completely forget Substance D from A Scanner Darkly? Or is that just too obvious?

  • Prozium in Equilibrium is a rather unusual drug.

  • Fuck Off Nathan Rabin, Dune is Epic !!!

  • With melange you can "travel without getting out of the place".

  • ...this bald motherfucker

  • what about the post button on YouTube? that's probably the worst drug ever invented.

  • @westpointe3 You're right! It makes people say some stupid crap.

  • Bloody Eye from Cowboy Bebop!

  • Soma is a real drug

  • they forgot mugwump jizzum!

  • ever hear of a movie called 'A Scanner Darkly'?

  • @antheman021 I could never forget that movie. Weird effects.

  • Babylon 5 'Dust to Dust' Addictive drug, allows non-telepaths of several races to probe the minds of others, experiencing all the victim's memories and thoughts in the space of a few minutes. This leaves the victims unconscious, and telepathic victims never recover. The more often Dust is taken, the more is required the next time. Dust was originally developed, apparently still being produced, by Psi Corps to induce permanent telepathy in normal humans; the experiment has been a failure so far.

  • @kiwicanuck1973 geek alert ! geek alert ! :P

  • U4EA= Euphoria.

    Why did I notice that?

  • GREASY

    

  • Cake. Its effects the shatners bassoon.

  • Nice reset button in the middle of ur forehead

  • I'm not sure what the point of this video is...

  • The navigators in Dune don't use melange to fold space; the engines on their ships do that. The navigators use the spice to see ahead in time, so that they can chart a safe route for their ships.

  • SUBSTANCE D!

  • Stimpack

  • they didn't cover the most famous one! Some people!!!! the drug that is like perfect! gives you a high with no bad side effects (and you can control how long you want the high)

  • the spice must flow

  • adrenochrome...Fear and Loathing...come on guys

  • how about prozium from equilibrium?

  • wtf dune is a masterpiece!

  • Aw man, I would take melange but I definitely don't want blue eyes. Dammit.

  • What about Skooma from Oblivion?

  • Wow, didn't even include "A Scanner Darkly."

  • The consciousness-recordings in Strange Days - best drug ever.

  • SOMA is not a fictional drug... generic name Carisoprodol and is a highly addictive muscle relaxer. I had a girlfriend that was strung out on the stuff... bad, bad news!

  • I guess they don't know anything about Dune and they yet still talk about it...

  • I'm surprised Jacob's Ladder wasn't on the list...

  • @Canonpixmalogitechko I forget, what drug was he on in that movie? I havent seen it in forever but I just remember hellish demons appearing apparently due to the fact that he was facing eternity in hell. Or maybe he was on morphine after being shot down in combat. lol I just dont remember

  • @phiten40 It was called "the ladder" hence the title ;)

  • all the drugs from the fallout games :P

  • The drug from the movie 'Limitless' was awesome. Unlocks the smart in your brain haha

  • YOU wanna buy death stick!?!??! YEAH SOUNDS LIKE A SWELL TIME.

  • What about death sticks in star wars?

  • Plutonium Nyborg?

  • "Supercool" UCB

  • @HolyCity2012

    exactly what I was thinking!!! when I saw this that was the first drug that came to mind

  • mgh from marvel?

    red sand from mass effect?

  • how about jet? its basically speed and cocaine mixed togethor

  • @viking977  thats not a made up drug

  • @thull21 jet? ya it is

  • when are they going to get rid of that horrible jungle/world music???

  • Pretty sure Soma is a real drug.

  • STrangers with Candy is the funniest comedy to ever hit tv!

  • SOMA!

  • How about Twelve?

    

  • What about Dr. Flopper?

    I mean seriously you drink that and you can fall from great heights, with stand explosions, and cause small thermonuclear explosions by falling forward!

  • Well, the drug is from the story Dune, which is pretty universally assumed a masterpiece. The movie is another issue.

    But how can you forget Soma from Brave New World?

  • I love Dune and GTA3 they are both masterpieces in their own way.

  • omg. That bald faggot did not just compare Dune to that overated animated piece of shit Avatar O.o

  • Nuke from Robocop is a winner. Can you think of any other drugs that can be used (unsuccessfully) to fuel robot law enforcers?

  • Skooma from Oblivion! wtfffff!

  • Noone said fluid carma from Southland tales?

  • FUCK THE BALD ASS HOLE I'LL FUCKING KILL YOU!!!!!!1

  • Skooma from Mass Effect!

  • @KongKyrre skooma from mass effect? no!

  • @thull21 Oh snap! I meant Oblivion! OBLIVIOOOOON! I'm so sorry.. Please forgive my heinous mistake! :(

  • im literally on soma right now after having had back surgery. its a name given to a muscle relaxant. hth

  • NZT!

  • Milk plus Drencrom. Real horrorshow!

  • I laughed so fucking hard when he started talking about Pacman.

  • NZT from Limitless

  • Wrong! Melange does only two things: increases prescient awareness and longevity.

  • I think my user name is my vote...

  • Zydrate from Repo! The Genetic Opera.

  • Valkyr from Max Payne

  • best drug is the stim, it even makes your rifle fire faster!

  • Where the fuck is Prozium, that's a pretty cool as shit drug, control masses with it in a fascist state.

  • There was a book I read in high school called Vert, I don't remember much about it other than one of the main characters was named Desdemona, but I pronounced it, Desmodesma, the whole time in my head and secondly, the drug I believe was called vert and it came in the form of a feather that one would shove down his throat... I think...

  • NZT c:

  • They didn't mention Polydichloric euthimal, the drug in Outland.

  • adrenochrome from feat and loathing in las vegas

  • The Spice Extends Life. The Spice Expands Consciousness. The Spice Is Vital To Space Travel.

  • Soma is a REAL DRUG! Carisoprodol, a muscle relaxant.

  • Formula 451 - POS451, the Power Of Suggestion. OhhhhhhhH!

  • A Scanner Darkly was the worst movie ever.

    That's why they didn't put it on there.

  • @MrTyWebb1 >implying Strangers with Candy wasn't the worst series ever.

  • cool :] i didn't thinkAv club would cover video games for there stuff 

  • I was so surprised that you didn't use Nuke as one of the primary examples

  • SOMA from Brave New World?

  • No Zydrate?

  • The Spice must flowwwwwwwwwww...

  • @superskh Wormsign!

  • is that Rory from accepted at 3:18 ?!

  • @MegF142857

    Definitely worth reading. And if anyone reading this is interested in Dune's history, check out the Machine Crusades series first.

    The guy in this ticked me off by not crediting Frank Herbert, and missing the whole frigg'n point of the spice melange, that it cannot be synthesized. He also assigned it some of the attributes of the Water of Life, a separate drug.

  • Soma, Brave New World.

  • NZT from the movie limitless

  • Red kryptonite

    

  • Never heard of Dune until today, and now I'm totally gonna have to go check it out!

  • @NegritaTanRica "Dune" is based on sci-fi novels by Frank Herbert, which are better than the movie. Definitely worth reading.

  • Dune is a masterpiece, those fools.

  • @Kapr1Sun meh

  • @Kapr1Sun yeah this is why i rarely watch these..they always act like something very easy to understand is very hard to understand....yeah the movie makes no sense except for all those people that get it....hmmmm IQ check pls

  • @Kapr1Sun They're just critiqueing the movie, not necessarily saying its awful. I for one love Dune as many do, but I also see its flaws and silliness at points. Its all in good fun.

  • @Kapr1Sun the fucking idiots seem to have left out the fact that in dune the i'll effects of prolonged usage of spice cause you to become a grotesque misshaped ball of brown meat that is incapable of sustaining it's self out side of an atmosphere of pure gaseous spice, and ignored the fact that the enhanced mental and psychic abilities were only available to women and paul as spice-water would kill the men who tried so yeah the don't know what the fuck they are talking about.

  • The spice is the life.

  • La Victoria's orange sauce

  • No that's not Steven Colbert it's Al Gore.

  • Dust from Babylon Five. Grants telepathic abilities to non psychics. Lets you share another's dreams.

  • No Tracy Gill. No watch!....

  • Really.. Spice ain't a drug.. Silly old men..

  • 4:40 surprised me lol

  • They never said what real drug Spice is comparable to, yet openly endorse it... I'm guessing pot?

  • dont forget death sticks from the newer star wars movie

  • ...So 3:30 is in fact Stephen Colbert. Thank you wikipedia

  • 3:30 Stephen Colbert? Is that you?

  • Is it anything that affects the mind? What about-- THE HYPNOTOAD!!!

    ALL GLORY TO THE HYPNOTOAD!!

  • I have always wanted to try Nuke from RoboCop 2.

  • P.O.S 51 from formula 51, nuff said.

  • GTA drug seems unerving? i was laughing my ass off on the clip LOL i wanna play that game to find out

  • hey, finally a videogame featured in the AV club!

  • fix the sound, asshats

  • Red Sand, anybody?

  • JEFFREY!!!

  • Chia Mr. T, FTW

  • spice ftw

  • Lol I will stick with weed.

  • tigerblood 

  • Soma is a real drug, its a muscle relaxer.

  • "If anybody ever offers you cake, throw it back in their face and tell em to fuck off!"

  • Soma isn't fictional.