From RNA to Protein Synthesis

[bellanstellan]

I love youtube, think I'll pass the exam tomorrow

[sstusia]

Anyone else have an exam tomorrow?

[soymilk135799]

It's almost like these molecules can think!

[lavadog34]

picture paints a thousand words...a video so much more

[TheRedWolf102]

waaaaaaaaaaaaaaaaaaaaaaaaaaaaa­aaaaaaaaaaaaaaaaaaaaaaaaaaaaaa­aaaaaaaaaaaaaaaaaw



[CrimsonGlory999]

watching this creepy video at night does not make me feel any better about my ap bio midterm tmrw.

[reddupo]

What happens to the original unwound dna? It just builds up as waste or something?

[921milanista]

@reddupo no it recombines by the help of an enzyme

if it went to waste then all our dna would be gone

[sstusia]

@reddupo No. When helicases untwisted the DNA helical structure, single stranded binding proteins held it apart. This created a separation between the two strands called a replication bubble. This allowed for the copying of the mRNA strand. When copying of the mRNA strand completes, it detaches, and the two DNA strands rejoin.

[ct501st]

when the mRNA goes through the ribosome, is it from 5 prime to 3 prime? or 3 prime to 5 prime?

[UnknownZealot77]

im going to start conversions about science on religious videos.

[rowa3ify]

test tomorrow!

[JoshuaBenjaminA]

i like justin bieber

[ben567567]

this contradicts the bible.

[josemagus]

@ben567567 That is because the Bible contradicts truth.

[QBisbest]

LMAO, I got a 4 a couple of months ago on my AP Bio test and I remember none of this.

[EcKoSniping]

Fyi he said hundreds per second...he's wrong it's trillion per second

[squishyfroggie]

SO helpful. thank you!

[conbriorules22]

OMG! SOOO HELPFUL! THANK YOU!!!

[mackles]

Man this is easy, I'm a 4 week old fetus and I learned all this stuff (central dogma, aerobic respiration, SNRMP, protein assembly..) in my second week!

[mackles]

just out of curiosity...are there are conservatives watching this? Something tells me no...

[josemagus]

@mackles You have no idea what a conservative is. A conservative adheres to the constitution, just as a ribosome adheres mRNA. A liberal (communist) adheres to shit (chaos).

[mackles]

@josemagus don't you have a bible somewhere to be thumping?

[TeamFuMe]

@josemagus You, sir, are a fucking retard.

[josemagus]

@TeamFuMe Wow, what a clever retort. Your friends must think you're smart. Unfortunately, your friends are the apes that you are devolving back to.

[TeamFuMe]

@josemagus Lmao! Another typical conservative ''argument''. You're the reason behind the destruction of our liberal society.

[josemagus]

@TeamFuMe Your are not very cogizant of history. John Locke and others defined liberalism as freedom FROM government. This got distorted to freedom FOR government at the expense of the freedom for the people, and in the US, started with the progressivism (communsim) of Woodrow Wilson. The US was founded on conservative principles and remained so for over a hunred years. It was Tytler who said that democracy is only a temporary form of governmnet - it eventually dies of liberalism.

[xLovee]

studying this material late at night is okay until the creepy music starts playing. then i proceed to shat my pants.

[XraneXify]

why do they alwyas put creepy background music in animated biology videos like this. they did this with mitosis and dna repllication too wtf.

[Beabeforever]

kids today are sooo lucky! they see this video and "get it" while I had to listen to a boring lecture and use my imagination to know what the heck was going on

[arthur121xD]

thumbs up if you are now in 8th grade... knowing nothing about biology... and the only one who may rescue you before the test is youtube and this video

[iiwDgiB]

@arthur121xD wtf you're doing protein synthesis in the 8th grade? I mean it's possible but I never learned this until grade 12 of highschool. lol

[arthur121xD]

@iiwDgiB lol

[Selxis]

@iiwDgiB I can't believe any of this stuff is taught to you in high school. I'm a 23 year old medicine student, studying at university and I'm only learning this now. Maybe they mention the central dogma (DNA to RNA transcription and RNA to Protein translation), but I can't imagine they're doing anything in depth from there on.

[iiwDgiB]

@Selxis Yep, In highschool grade 12 I learned the central dogma as you said, basic stuff. I'm in first year university and so far they only reviewed the same as high school. Thats a 4 year split, science curriculums are always updating. :/

[michaelfreudiger]

@Selxis i have taught lectures for it in high school as a guest speaker, if you want to see what the lecture i produced for the school (and now used by a larger conglomerate), google my name and add "amgen" at the end of it, it will be the top entry for brucewallace biotech series. believe it or not, in some high schools, they are actually running gels, and creating engineered plasmids. amazing how fast some curriculums advance right?

[reddupo]

@arthur121xD

lol, 21 here but i know that feel bro

[muffzkis]

THankz 4 d vidz mr. MIRANI. u iz d best

[Eragon537744]

seems most people who watch this are fucked

[dbzHRepizode]

@Eragon537744

LOL

I'm being examined tomorrow (biology) and it's complicated so I'm the one of those "fucked" who watched this video to understand it. xd

[DASUPACHICKEN]

DICK SLAP!

[117DieHard]

how does this get 1,074,621 views!!?!

[Becbec292]

@117DieHard because alot of kids do biology

[TheDailyOriginal]

@Becbec292 lol,yes.



[GumBreed]

INSTRUCTIVE VIDEOS, WHY U NO SPEAK ENGLISH!

[romiesgirl13]

I like the magical amino acid bonding hahaha

[yddam33]

where did you get this video from?

[horsefreak1982]

i have an AP Bio essay on this tomorrow.. never learned it.. im fucked.

[nasir91]

excellent

[FaithAndScience11]

My teacher sucks. And I finally understand. :)

[luvtheLordJesus]

this really helps...seriously...I feel a little better now....lol

[spotlightman1234]

this is happening in me...

[9klam9]

@spotlightman1234 lmao

[sckettch]

....I'm so fucked

[iWriteUinMyDeathNote]

@sckettch So am I...

[sckettch]

@iWriteUinMyDeathNote HSC biology?

[M6cha]

studying? I'm here for fun

[mkhanyisi1]

wow i just did A PRESENTATION ON THE CENTRAL DOGMA OF MOLECULAR BIOLOGY. INTERESTING REASECH

[gmawesome1]

im studying protein synthesis for a quiz at the last minute

[iamlea]

What about release factors, A-site, p-site, stop codons... I need details man!

[KillerPiano]

who else likes the music for this video?

[jasonbaggenstos]

stupid fucking scary music ruins my concentration

[lnetz77]

@jasonbaggenstos hahahahhahahah!

[XzyzzyxxX]

Got a Midterm in 2hrs haha

I am so not ready for this Cramming For the Loss

[elefantsnablar]

0:56 scary ass music o.O

[swimstudzs]

its scary how watered-down this is

[ivantodrihumpu]

@coolashley97 not hard to tell what you're thinking about.dna makes me horny as well.

[dritzzz360]

this is too easy!

[lukeguy97]

Well damn.

[coolashley97]

i though that was a dick 1:56

[19MacDaddy95]

@coolashley97  YES WTF???

[itzraywhy]

@coolashley97 thanks for making my day in bio today exciting... haha the teacher was wondering what we were all laughing about..

[butzel101]

@coolashley97 dude... your dick must be pretty fucked up

[ColonelBatman]

Anatomy is kicking my ass.

[deadpool93x]

I think there's been a mistake at 2:00

"leaving the ribosome in search of another, identical amino acid."

isn't the "ribosome" supposed to be a tRNA?

[RizzoRatchet]

@deadpool93x Yeah, I think you're right. I didn't even catch that at first.

[tinjan94]

@deadpool93x I don´t think they meant that the tRNA was the ribosome, they just said that when a tRNA leaves, the ribosome will search for another one? oh gosh I´m not good at this xDD

[blazfuturama]

strange but hey, whatever works!

[thecrisisification]

so much better then my prof

[perfectengineers9]

AMAZING VIDEO ,It helped me alot in my exam



[thatgirlkendalll]

ONE OF THE BEST VIDEOS I'VE SEEN. IT TIES EVERYTHING TOGETHER. THANKS!!

[MrEndott]

This may seem sad, but I think this whole process is beautiful!

[chapisql]

@MrEndott It isn't sad, it is one of the wonders of the human body, which to date is still a mystery.

[KidsDeserveDinosaurs]

actually fuck making a storyboard on the process of protein synthesis :(

[imanganation]

Human Bio exam tomorrow. This actually makes sense though.

[Koop380]

DANIEL SNAKKER OG SNAKKER!...

[J0nttOO]

The teacher has been talking about this for about a week now. I have no fucking clue what it's all about

[SuperEverythingman]

Who else is fucked for their final?

[Mrkingfrank101]

totally failing my micro test.

[designerkitten]

where do these ribosomes and trnas come from? the air? are there ribodomes and trnas floating around the air that we cant see? looking for an m-rna?

[airrifleguy]

@designerkitten Ribosomes are made by the nucleolus. In eukaryotic cells, tRNAs are transcribed by RNA polymerase III as pre-tRNAs in the nucleus.

[Nuthing2Do]

@designerkitten basically floating around in the cytoplasm of the cell.

[mappingtheshit]

@designerkitten Actually yes, from air... Millions and millions years ago we had atoms that were emerged due to some event (some call the event Big Ban, some call it the collision of superstring membrane and etc). As the atoms emerged with the help of quantum physics laws they began to synthesize with each other forming different types of molecules including those that form the air. As the process went on we got those molecules that form all ribosomes

[slasherblue]

Brilliant <3

[KenLopezYokohama]

DAMN IT I HATE EXAMS

[organtheif]

Sadly, 97% of Facebook users won't repost this. When Jesus died on the cross He was thinking of you. If you are the 3% who cares; repost and like this.

now i don't normally repost things like this...but after whatching this video i smoked some weed and am now converted and in a healthy diet. I am now thinking about trimming my pubes

[wert0234]

this is soo boss

[mindlessacts]

My brain hurts....

[MrRidred]

great graphics



[emmceeist]

Any People Who want a very simple explanation:

Step One: Transcription

- Info on DNA copied onto an RNA molecule

Step 2 : Translation

- Th e info now on RNA Molecule is used to make new polypeptide chain.

Step 3: mRNA is held by ribosome and tRNA links correct amino acid together to make a polypeptide.

[sckettch]

@emmceeist My god. Thank you!!

[adlee0705]

wow! its all happening while we watching this~ subhanallah !

[ISMAILdude93]

WHY SPEND MONEY ON TUTOR WHEN YOU HAVE THIS !!!! SO FREAKIN AWESOME !!!!

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[OWLCITY54]

@virtual23885 that is so out of topic

[CindyRoxc]

This is too confusing

[airrifleguy]

DNA splits and RNA is formed, Then RNA gets transcribed and turns into m-RNA, m-RNA is tarvels and attaches to ribosome ribsome sub unit which "gets the attention" of a t-RNA, the anti-codons interact with the corresponding codons on the m-RNA, larger sub-unit of ribosome comes along which attaches to the smaller sub-unit making a working ribosome, polypeptide chain is being made from the interaction between t-RNA and m-RNA, chain folds and an effector molecule activates the protien. Helpful?

[designerkitten]

@airrifleguy you are the man. thank you

[airrifleguy]

@designerkitten You're welcome. 

[Sparklillian]

RNA polymerase unwind the DNA at the Promoter/START signal on the DNA strand, and copies it into mRNA, which moves out of the nucleus & into the ribosome (rRNA?), which is made up of 2 subunits that can disassemble/assemble. The tRNA goes into the ribosome & attaches itself to the its codon, releasing it's protein, which binds w/t other proteins. Finally, when the whole thing is finished, it's folded & sent out 2 where it is needed. Why it happens, the body needs proteins to survive! No space...

[pokemon9505]

OMFG THANK YOU SOOO MUCH FOR THIS VIDEO!!! <3

[minidude111]

LOL read your text book first, then watch this. Now i get it so easily.

[MsAgnosticatheist]

These videos never explain why these processes are happening. Why is this happening? What makes them replicate, and how do they know where and what to do? I understand evolution but on a molecular level, what is driving these molecules to behave as they do?  Anyone can you tell me? I am having a really hard time comprehending the inner workings of cell.

[TiLine1]

Reply to MsAgnosticatheist:

These processes are happening to sustain life. Without proteins the cells cannot survive and therefore no life can exist. These molecules know where/what to do because there are specific signals within the cells that attract them to do their jobs.

To learn more study cell and molecular biology for the rest of your life, but don't get too disappointed to realize that at the end you will know nothing. No one will ever be able to fully understand the miracle of life.

[NorthForkFisherman]

@MsAgnosticatheist Certainly be glad to try. What's going on is chemistry. The proteins have a certain electronic coifguration that attracts the corresponding pattern in the DNA. The proteins are generally allosteric (change shape) due to their shape and composition of polar and non-polar (hydrophobic). I'm really restricted by character count, so take a look at the NCBI's online copy of "Molecular Biology of the Cell, 4th Ed.". It's a clunky interface, but it's all there.

[axeljordan1]

i dont get it

[MrNephson]

This guy speaking sound like the Mission Director from Rogue Squadron.

[lexinaut]

Visually fascinating and impressive. People who giggle a lot form a DOUBLE SQUEALIX instead of a double helix.  (A little humor helps you think about really complicated information).

[wtfthu]

Studying for my mid-year's. This was helpful, thanks!

[seaseabamba]

Ahhhhhh what??

[DarthScorpio11]

lulwut?

[Gretschdrummer7107]

Who else is studying for a final?

[MRAtPt]

@Gretschdrummer7107 I watched and got A+.

HELL YEAH

[TheKevtrevable]

@Gretschdrummer7107 me, im screwed

[xoxoRiverTamxoxo]

I do not like science x___x Thank you, this was helpful :)

[HighLifetage]

FUCK THE IB DIPLOMAA, I WILL ONLY HAVE TO KNOW THIS FOR TOMORROW, AND TOMORROW ONLY AND IM SPENDING MY FREAKIN ENERGY AND NEURONES STUDYING THIS !! FFFFFFFFFFFFFFFFUUUUUUUUUUUUUU­CCCCCCCCCCCCCCCKKKKKKKKKKKKKK

[Xshado2]

@HighLifetage dude, its really not that hard -.- im getting a 7 in biology and I hardly pick up a book, pay more attention in class....

PS: you think HL bio is hard? rofl come to HL math, and we will show you what the big boys do

[HighLifetage]

@Xshado2 Congratulations for your 7 big boy.. Now, the difference here between you big boys and I, is that I did SL maths, but the time u big boys spend caring about the IB and studying for HL Maths is the time I spent going out with my friends and girlfriend and not caring at all for this shitty IB.. Again, congratulations for being a HL maths boy, i trully envy you and the rest of your friends the big boys!!

[Xshado2]

@HighLifetage Im sure going out and having a girlfriend will help you succeed in the future. Good luck

[Rao665]

@Xshado2

In a way, HighLife there is going to succeed.

Experience and street smarts over book knowledge any time.

[Xshado2]

@Rao665 I'd rather stick to book knowledge, get into ivy legue and be welcomed and hunted by hundreds of companies than to rely on my "street smarts"

[Rao665]

@Xshado2



So you'd rather live in a bubble, and earn yourself lots of cash. To each his own.

[Xshado2]

@Rao665 Who says I live in a bubble? I study on weekdays and go out once on the weekend? And in that weekend I party like no person partied before.... But after that, I get to doing my work...

[Rao665]

@Xshado2

please be quiet. my brain hurts trying to watch the pretty colors. I need to focus.

[immortality64]

Awe some!! I just Replaced my teacher with youtube with a replay button!

[UpSyndrome2]

Yep im defo failing biology again tomorrow

[IPKVIDS]

tbh i find this confusing :(

[gwk4657]

Very nice vidio awesome

[gxas2]

makes so much more sense

[atph120890]

does only one ribosome do the protein synthesis after M-RNA gets out of the nucleus?

[jamiemicka]

no mRNA processing?

[graffist448]

this shit is crazy! I love youtube videos hat explain these things so well. Reallly really speeds up the time I spend studying.

[CLSkill]

@outdoorsman2013 Must have failed math, because it is 50, not 48, retard.

[FuckTheLawBitches]

@CLSkill It's from 2 months ago, back then, it were 48 people, not 50. Must've failed common sense, 'retard'.

[bboy9955]

soooo this is kinda wrong... Dna polymerase unzips first

[0oSnap]

@bboy9955 Not 'Dna polymerase,' lol. It's RNA polymerase that unzips the double helix.

[Br0nXb0y96]

To be honest i just think teachers and scienctists make this stuff up to make our lives miserable

[skyinmind487]

@Br0nXb0y96 lol not quite...this is literally the truth about why u are the way u are...from your pink finger, to the shape of ur head, to the size of ur dick.....its dna

[MCARx0]

i seriously do not understand this stuff. wtf. i could watch this 40 times and still not get it. its a good video though im just stupid. i have a huge test tomorrow and im gonna fail :((((

[Greyreptilian]

@MCARx0 Did you fail?

[MCARx0]

@Greyreptilian i actually didnt! I got a 90% :) I'm so surprised hahah

[Greyreptilian]

@MCARx0 Huzzah!

[dbanjeezeez]

lolwut?

i'm so lost.

this is what i get for sleeping in class -.-

[DawnBreaker1100]

@dbanjeezeez Do a barrel roll!

[freestylefurby]

How the hell did people discover this. It is insane. Useful video though.

[MsCupcake504]

Wow this was really helpful. thanks

[metalboostable]

where is the polymerase...

[thekaitlynmusic]

@metalboostable the polymerase is the enzyme that creates the base pairs complementary to the DNA strand :)

[jeeennn09]

@metalboostable polymerase and protein are the same thing:)

[hobojo64]

h8 the guys speeking

[Rita248]

You saved my life *-*

[jay8950]

good video, creepy music..

[Annabelleendd]

OH MY LORD. i actually understand this !!!

why doesnt my biology teacher save her breath and just put this on?

[Hellstrom03]

Where does this video come from?

I would like to use it as a reference in my biology :)

[shakedown33]

Penis @ 1.55

[Critiqu3]

Oh my god THANK YOU for posting this. It's so nice to be able to see things happening instead of staring and stationary pictures and reading boring, unnecessarily long explanations.

I never understood the mechanics of it until now! Ugh, I seriously thought the mRNA strand was being elongated, not the protein. I hate my AP Bio teacher with a passion >:/

[MyTenToes]

I am doing 4U Bio by correspondence and I am panicking. It is so much harder than I realized. This vid has made me feel a bit better but I am still stressed out because I chose bio as a university major and if I fail because I am not good at it I will be devastated. I am interested in the subject and it leads to so many fantastic jobs!

[mcskillet987]

my bio teacher is fat and lazy and didnt teach me anything and i got a test on this tomorrow, this was the only video that really helped thanks so much!

[Caesarslegion1]

CUNTFLAPS