RNA Animation

[thetheu3]

se fosse em portuges D:

[PainHoarder]

It's like a space movie.  And so fine-tuned and precise at such a small scale, hard to imagine.

[djbiggun1]

she said fungee

[LAxCECE]

And this makes sense how....? If anything now I'm even more confused. WHO CARES ABOUT THE WORMS OR WHATEVER.

[idq000]

Thank you to whomever created this video. There were just so many abstract concepts that finally came together with this animation. We actually did a lab that allowed the C. Elegans worm to express heat shock stress using the hsp70 promoter sites. We had to do amplification of mRNA and proteins like this. I still hate Bio.

[BonErd13]

thnx a l0t...vids like this are very helpful f0r students like me :))

[ophello]

This makes absolutely no sense.

[LAxCECE]

@ophello i sooo aggree

[stacyxxy]

i wish i would"ve paid attention in school...im so fascinated!!! my New Years resolution was to watch less tv and spend less time partying and learn more about the function of the body. I have a long way to go!!!

[NaNa00CaNdY]

her voice sounds like Meryl Streep in the devils wears Prada !

[EnkiSvohden]

This is like computer programmed machinery on a cellular level. Awesome stuff indeed!!!!

[befkah]

g pas compris la dernier partie

[dilabop]

of course of course

[jhonjahider]

estaria bien si le colocaran subtitulos para los q no entiendan el proceso... y el ingles tambien...

aunq esta muy bueno el video

[tonehh]

C. elegans is Caenorhabditis elegans. ITs the same one they found apoptosis in.

[elena2809]

aaa>>>>/////

[DrzSpectre]

Can someone write what the voice said the first 25 second? thanks anticipated

[Isiik]

RNA interference was first discovered in ... (some type of worm probably)

when long double-stranded RNAs were injected into a worm's gonad. A standard way of introducing trans-genes into worms. They blocked the expression of endargenes (? can't make out the word) genes in a sequence-specific manner.

I hope I've heard it correctly. Not a native english speaker.. sorry if there are any mistakes.

[gogoutoobe]

"endargenes" =

endogenous genes

(genes present in the organism- as opposed to exogenous genes)

[streamreflections]

the "worm" = C. elegans

[reducingASH]

god's technology = something that is in front of our eyes yet we still cannot create it ourself like he does it in a split seconds.

[Frankgone2010]

Gloria a Dios!

increible!

[JakKin0]

GIAMMO è BELLO

[JakKin0]

eh be

[steph200410]

ughh and i thought i got it before i wacthed this vid. damn :(

[spartarius69]

Protein complexe between ribosom site and nuclear place give to the RNA a cirular form !

[lokomarani]

Eu gostariia da tradução, não consigo traduzí-lo! Por favor me ajudem, preciso fazer um trabalho e esse vídeo é perfeito!

Aguardo resposta.

Obrigada!

[lokomarani]

Eu gostariia da tradução, não consigo traduzí-lo! Por favor me ajudem, preciso fazer um trabalho e esse vídeo é perfeito!

Aguardo resposta.

Obrigada!

[lokomarani]

Eu gostariia da tradução, não consigo traduzí-lo! Por favor me ajudem, preciso fazer um trabalho e esse vídeo é perfeito!

Aguardo resposta.

Obrigada!

[sausage4mash]

this was well over my head ,but interesting to watch , excuse my ignorance ,but i got to thinking how are Slicer's made ,are they simple chemicals that have the effect of slicing ? idiots explanation pls :-)

[BernierCR42]

it would be an enzyme.

[Kirkwhisper]

"excuse my ignorance ,but i got to thinking how are Slicer's made ,are they simple chemicals that have the effect of slicing ? idiots explanation pls."

Don't feel alone. The experts don't have a clue either. In fact, they don't know how that tiny machinery like this originated at all since it takes the process to make the machinery in the first place!

Toss evolution.

[sausage4mash]

na toss god of the gaps

thanx

BernierCR42

[Waranoa]

Still, the end of the video makes matters quite complicated. Why would you want to have so much RNAi to be duplicated? I have some suspicions but there's some information missing from this vid....

[wogus86]

The video mentions "amplification." dsRNA works for silencing specific genes. If you want a gene silenced in one cell you might want it silenced around neighboring cells as well, which is why there is so much being produced. This way it can be sent out and amplified. Also, remember this study is fairly recent and look for Fire's paper which awarded him of the 2006 Nobel Prize of Med. so information missing out on the video might just be unclear to everyone else in the field.

[worldismarble]

the two dicers look like clones undergoing reproductive activity while dicing the RNA.

hooray for science!

[LohGr0r0r]

My brain is melting and I hope to rectify this problem.

[raycogarciap]

thanks for the help...

[Waranoa]

One question though: Why does the slicer-mRNA complex target endegenous RNA?

[erospsyche]

You were listening?! Man I am stupid

[Waranoa]

Yeah well, I'm a biology student :P I'm sure you have different talents ;) j/k

[Waranoa]

Damn I understand now! The Slicer targets homogenous strands, which will NOT be endogenous but VIRAL! Woohoo! Slicer is cool :P

[erospsyche]

u must have like a gigantic brain. I am so jealous right now! No offense

[Waranoa]

I'm studying for my RNA exam on friday lol :P

[Waranoa]

Wow really nice vid!

[jazyfe]

waaaa. *drool* i mean yea that realy makes since.

[menpos]

jejejejeje

[abhijit00004]

must go for oscar!!!!

[Arifer95]

chim

[TheMassaKiller]

If you understand all this complex stuff, Biology is a great and fascinating Science :)

[wessellonus]

wow, i have biology and this will be my test for next tuesday, but it is so incredible smart, something complicated as cant excist, i just can't believe it

[F1V]

thank you that was helpful

[Ryeback101]

Seriously good! Thanks for making this

[fairbro25]

this is an incredibly cool video!

[Divine009]

am i meant to understand this?~~

[dxrules234]

this made me ace my test...thanks

[memoyout]

Congratulations.

[ToobYew]

Very informative video.

[apoch4]

no not really lol

[renoufarnold]

is there any actual pictures of a real dna strand? im assuming they do not look like colored dominos

[garouHH]

Pictures of the complete and winded strands? Yes, google for "chromosome". Of the domino-sections? Not that I know of, they are, after all, only a few atoms big.