DNA REPLICATION

[malbert34]

Simple explanation of DNA replication is as follows:

1. DNA helicase unzips the DNA Double Helix into two separate strands.

2. DNA polymerase adds free nucleotides to the complementary base pairs.

3. Hydrogen bonds form between the complementary base pairs.

Double helices are semi-conservative because they each helix is made up of one new and one old strand of DNA.

[MegaSerena19]

Perfect VDO!!!!! :D

[G1ingy]

I still don't get it. Why does one have to be made from okazaki fragments while the leading strand can do it in one go? Why not both use okazaki fragments or both use DNA polymerase to do it in one go?

[bboydjoe]

@G1ingy cuz u need to synthesize the new strands from 5'->3'. so DNA pol III attaches to the 3' end of the template, and goes from 5'->3'. when it reaches the fork, it must also go from 5'->3', but since the 3' end of the other template is at the fork, its hard for DNA pol III to attach there and do what u said, so it must be formed in fragments.

[Msholyangel17]

Please help here? I am so confused. DNA synthesis is 5' to 3' but the new template made is 3' to 5' right? What about the nucleotides being added? Which direction does that go? The nucleotides are being added to the existing strand in 5' to 3' but after it is added and sealed by ligase, the new strand is antiparallel which is 3' to 5' right? SO, if I have a question which asks the nucleotides are being added in what direction? What is it? 5' to 3' or 3' to 5'???

[samsta001]

@Msholyangel17 DNA synthesis of the new strand is 5' to 3' so it would be added to the existing strand from 3' to 5'.

[Fairieswell]

Just want to add this. DNA Polymerase I is the enzyme that replaces RNA primer with DNA nucleotide.

[AQhockey44]

these videos are very helpful, except im still having trouble understanding transcription

[susu318]

realllllly good

[30792ajs]

very gud video.. 

[kuschelgiirl]

really good!



[ephraimtorres]

This is the best video among other DNA replication videos. Short and simple but very clear. Thanks!

[rastarigate]

@sailorlunar

prove it

[chillskid]

@sailorlunar shut up. 

[oommaanniiaa]

it is very pinificts

[namachwed]

This video is really good, far more helpful than all the others the search result came up with. And for those of you condemning this and all other videos calling it an epic fail, a disaster and so on, let's see you make one of these videos. Be it simple, this animation stuff is NOT as easy as it seems so be appreciative of these people's efforts uploading them to be shared instead of dissing them all the time.

[tebatebarajab]

WELL DONE

[PnoyBrandon]

fail

[azn7x]

terrible

[RammatRamzi]

Man. There really is no such thing as science fiction/fantasy when I see stuff like this.

[Eye2EyeIIIV]

DNA = Do Not Abort

[gatorpower]

The most interesting part about DNA replication is what happens on the lagging strand. That's not even covered in this video :(

[rockeritza22]

@gatorpower well, it's an old video.

[sukkittrebek]

@gatorpower What do you mean? They specifically covered Okazaki and RNA primers and ligase. It's more than a lot of these you tube videos cover. A lot of them don't even mention the lagging strand. They just show to molecules of DNA polymerase cruising along opposite each other at the same speed.

[Goodfellow7]

@gatorpower It is covered... at 0.45(ish) in the video.

The lagging strand is the one on the right.

Primase synthesizes an RNA primer, allowing DNA polymerase III to attach to the primer, so it can form short fragments of DNA called Okazaki fragments.

DNA polymerase I and other enzymes then replace the RNA primers with DNA.

Then ligase covalently joins the tiny gaps left behind so the Okazaki fragments are joined into one continuous strand of DNA.

The video said essentially the same thing.

[hifatpeople]

@gatorpower since when is it interesting at all? unless your making X-men

[bekhiet89]

Cám on chu da post cai vid này lên

[cikguku]

NICE

[samimoh8]

nice work

[universehappy]

Come take part of the most viewed video THEONEBILLIONANDMOREVIEWSVIDEO Benefits will be given to people who need food and care..the more you clic the more you give :)

[XHUMBITO1]

Thanx for this video, it helped me a lot !

[zmoney682]

If you don't understand this, go back to the basics of DNA...

[DADABallerina]

that was waaay too fast to understand and explained in a complicated way Ö.Ö

[antonickah]

this video was well mwde and thought through and it helped with the home work i was doing so thank you

[limlynn999]

Love Genetics

[princessandbluemoon]

me too!! genetics is an awesome science :)

[mrdispensation]

Why, it all sounds so incredibly SIMPLE!!! :)

[nparsons97]

this was such a helpful video!

[hassanaboali66]

HASSAN

[NguyenEmpir3]

Would of been useful if this was a actual video.

[fr3ds4t]

Indeed, the Bible says world was created for our own ends (we=humans).

Well, I could say we were "created" in order to guarantee Escherichia-coli's survival.

[chillupsunday]

it's our believe that it's all GOD's work!!

[janneman666]

The magic of evolution, my friend. It happens. It exists. It's proven. Resistance against antibiotics is the world's largest proof of the existance of evolution. In 50 years we've created major adaptations in the bacterial genome by selecting resistant species. Something that would normally take millions of years... i Viva la evolucion!

[icequeenfirefly]

@Dressagebabie16 well i belive god created the beggining bacteria and then that developed into early speicies and then eventualy, us. i don't believe just one is true

[FlameNOH]

complicated

[5amGordon]

its a matter of understanding the big words.

[thewaythingsare]

Yep it is digital replication. And tiny errors in that process

may or may not be passed on by means of natural selection.

There is nothing mysterious about it. After 15 billion years of cosmic Evolution we have finally woken up and know what is going on. Its a beautifully elegant solution and no designer is needed or indeed was ever needed.

[Viperatut]

I can't stand people just blindly saying God did it w/o a shred of evidence. Also, it's not chance, but the product of mutations and natural selection.

[lawz41]

how can you not believe there is a God after the facts of science? His creation is breathtaking! dont try and tell me this all just happens by chance!

[atunnell03]

I definintely agree! It is so amazing to learn of all the intricate detail God put into designing our bodies.

[darkwhitty]

Sure it looks most likley a creator created everything. But who created the creator? Why do we need bull crap organized religion that has no relevance to science?

[6678]

Lawz, complexity of an organism doesn't entail that a creator did it. In fact if it was intelligently designed DNA should be fail-safe, but it isn't. It often can lead to disaterous mutations and other deformations. You also create a logical fallacy of false dichotomy, in which you entail that if someone believes a creator didn't do it then one must believe it to be chance.

[svengalistudios]

Sure you can name it "God", but please dont start assuming things that will only get you started in religion

[superfisto]

lawz41:

Do you think of God every time you learn something fascinating about the universe?

[fr3ds4t]

Let them be. Don't tell children Santa is not existing. May they find it out by themselves.

[splatuality]

Santa is an anagram of Satan .God is in good ..Evil is in the devil ..even words have a code within.

[fr3ds4t]

God is an anagram of Dog...therefore I shall praise my dog!!! HAHAHAHAHHAHA...please, don't make me laugh with these bullshits. You've been shocked by the da Vinci Code and you dream of it all night, I know. Go find yourself a girl and let this stuff away.

By the way: if words sound "similar" to other with similar meaning, it's because they've been made by the man to be similar. Etimologia, it is called. Nothing but an HUMAN product, my friend.

[splatuality]

glad you got the joke lol

[dalooloo28]

@fr3ds4t but God would've made that happen - He would've known humans would make the word dog be God spelled backwards and MADE it happen. and He would've made that happen for His own reason - maybe so that we would indeed praise our dog.

[fr3ds4t]

P.S.: I prefer reading Richard Dawkins, rather than David "Wicked" Icke. It seems you do prefer the latter, instead...

[splatuality]

Did you know that Infinity means that there's is room in this universe for everything ..No need to be so narrow minded .. Relax unwind let whatever beliefs take your fancy, whether its fairies, God or even your own purpose . Its all part of the show . And I definitely prefer Dawkin to Icke, although Icke with his aliens has a more comical approach lol peace

[fr3ds4t]

Alright...I got it ;D. Unfortunately I lack of humor when talking about these stuff, since I often hear a lot of people who actually believe them. As long as beliefs would take one's fancy, yes, I'd let them take it. But when people talk about 9/11, and use this bullshit as a "proof" of the Evil behind the story, that Bush is Satan and so on, I get pissed off. I just can't stand fairy tales to be put in a serious context like that. cheers

[rockjock7]

you need a girlfriend man

[kitsunetears]

what the hell does this have to do with anything???

[splatuality]

antonickan: LOL Its all about getting people to respond . And.. O LOOK ITS WORKING.

your problem is.. you think that being smart will allow you to Understand everything when all it does is highlight all that is bejond your grasp. Have fun . Dont worry about me ..I will live in bliss with my Ignorance.

[francolecco]

It's not GOD.

It's Chemistry.

[scoobdogg187]

Nature is amazing.

[darkwhitty]

Why make all these small vids? Why not 1 big one?

[caribbeangeorge]

This small vids are parts of the big one, moron

[conroy099]

you should shut up right about now

[mensmaximus]

Informative. I'm looking at the similarities between DNA and my rotating LED arrays.