Cardiac Output Part 1 Intro and SV

[kerryvp]

Great video!

[mrsmomo607]

this sucks

dallasreevees explains it so much better

check him out

[juliachemistry]

Thank you

[jakershunts]

could you write smaller I can almost see it

[DJMcIntosh93]

amazing. are you a teacher?

[jnick97]

Thank you for these videos, it is all making sense now! Excellent job!!

[MrMostafaMetwally]

Great

[bullets898]

Just a small question; i was wondering if 'ventricular elasticity' would be a factor determining SV? I know you mentioned it in preload (which I thought was just the amount of blood returning to the right atrium).

[hennagerdj]

Preload can mean simply the amount of blood in the heart just before contraction. But on a deeper level, it eludes to the Frank-Starling Law. In terms of the Frank-Starling Law, preload means the more the heart is filled, the more the muscle fibers are stretched, this pulls open the calcium binding site on troponin so that more stretch equals greater muscle activation (or contractility). I suspect "ventricular elasticity" also eludes to Frank-Starling. I hope that helps. dj

[therealsear]

@bullets898 Yes, ventricular 'elasticity' or compliance can have a profound influence on SV. Preload is the volume in the ventricle at end diastole, or right before the heart will start to contract to force blood out. If the heart is not compliant (stiff) it can limit the ventricular filling which will decrease your preload. This is not dependant on starling mechanisms but a result of changes in the heart muscle itself from a variety of illnesses (scarring from heart attacks, fibrosis of muscle.

[Beecher86]

Thank you.

[welches72]

Thank you for clarifying what I've read in ...more substance than we get in class!