Ribosome in action

[skahlida23]

simply amazing.

[IMAHMS]

mind blowing

[mrsunny811]

they look like terds

[ThinkingMan1809]

needs music and noises

[CHAPULINESLOCOS1]

is not really much fiction

[elleckz]

some people don't understand that this 'didn't' just happen randomly, it happened through evolution.

evolution as a whole doesn't produce organisms randomly, although there is a random component of it called 'random mutation'. What causes evolution to create things like what is shown in this video is that the dna that produces organisms that don't work (eg. have disfunctional roughER) is selected against because these organisms die while the organisms that 'work' breed and spread their dna.

[zenithar6666]

i never got how things are "brought" to the right molecules on time, isnt tis showing purpose

[RolfRomeo]

@zenithar6666

I'm in no way a biochemist, but I think brownian motion in the "soup" of molecules inside cells is what causes the right one to be in the right place in a somewhat timely fashion.

[zenithar6666]

nope, there is no way that could account for the timely arrival cyclicaly of trnas to ribosomes etc contractile rings at cytokinesis ete and calling it a soup defies and downplays the sheer scope of the organzation within the cell!

[RolfRomeo]

@zenithar6666

Ok, then. But I think you're overplaying the need for timely arrival. I doubt anything happens until the right reactants are available.

[zenithar6666]

nope, there are many instances where a a species would have died out if not for the appraent arrival of aprotien on time, anitfreeze is an example. There is such speculation its not even funny, simply becuase it has sequecne homology doesnt mean it evolved that way!

[13Pepinho]

marcooooooooooooo :D

[AssarLun]

The beuty of selected randomness.. I wonder what paths life has found on other planets.. There must be a zillion ways of information flow through molecules that awaits to be found. Truly magic.

[Spascebo]

it's wonderful......

[PakFa1988]

There is only one entity that created Everything this creating mechanism is similar to every technology we use ranging from making a spoon to making router to Cars & jets There is Intelligence behind everything around us we r not just a coincidence there is a maker behind everything around us FUCK anyone that says that there is no god here is ur proof go & study how we r created u will find the proof yourself

[cbernier3]

@PakFa1988 What is your job? Is it scientist? Where did you get your PhD? I AM studying how the ribosome was created and there is no god involved. It is all science.

[PakFa1988]

@cbernier3 I am not A doctor But Computer programmer & interested in Bio I Know That it is pure science But I know also that it is More Like the code that we write in our programs It need Intelligence to but in the computer to Create an initiator Code that u learn to Create another program, theory of the machine that build another machine All of This require Intelligence to but the creating code that builds another one we see only the creating machine & we say there is no god involved but

[PakFa1988]

@cbernier3 but we forget to ask who tough this creating machine 2 build in the first place in order 2 even say the word science we need 2 ask who tough this science 2 be intelligent and build another system "program" because the bottom of this is not the atoms but who created the atoms virtually from nothing because in order of those atoms 2 work like we see them work it need 2 be engineered from scratch with intelligence that but them in logical order 2 work right

[PakFa1988]

@cbernier3 right. like We engineer the computers & Build its software we cannot say that Computers build them self by them self unless we taught them to build itself by itself via engineering & coding that is AI now ask what is Natural intelligence? that is us humans & now ask what is what I call the Raw intelligence or absolute intel? that is god that is so intelligent to create & engineer all that we see from virtually nothing. Sorry for the long response cbernier3 :) bye

[bha1986]

that's very romantic

[SexyRaww]

oooh. sexy. lol

[shortMaddie194]

I'm confused. I thought that the riboseme's small subunit moves along the mRNA so that the tRNA in the P-site ends up in the E-site where it's released but here the riboseme doesn't move at all... accept from those chicken wings...

[shortMaddie194]

@shortMaddie194 ribosome*

[cbernier3]

@shortMaddie194 You are correct, but there aren't that many animations that are correct. People simplify things to make the animations.

[shortMaddie194]

@cbernier3 o.k thanks:)

[zastor99991]

Allahu Ekber !!!

[KECHEA]

This video is great. Very easy to understand and very clear. I wished it showed the next process. I love this. Thank you for posting it.

[Muuip]

Great presentation, thank you.

Does anyone know why ribosom may not work properly and what can be done about it?

[stefanieashlee]

it looks like a monster eating chicken legs. hehe.

[StickmanandCarl]

and puking them out the other side

[insectboy0]

Ribosome hay, reading up code, making proteins and most us. Transcription, protein folding, DNA, RNA, starting to fall in place

[Icesis72]

Better than reading it from the textbook :D

[Nanodev]

This is an automatic mechanism at the atomic scale. There is no friction or anything that could slow the process.

A computer processor is tiny and can calculate huge amounts of information per unit of time so why do you doubt?

[jonval212]

mRNA seems to be navigating on its own, with a purpose! I refuse believe it. Has to be random.

What's up with tRna hooking up with amino acid. Brought by IF2?, what does that mean? IF2 some kind of rail system? More speculation? Or do they really know?

This all happens at .001 seconds faster than a jet engine? Unbelievable!

What if some ribozymes coded at the size of houses, could start a whole new religion.

Church of the initiation factor 1,2,3

[Guarding]

Not sure about IF2 but I'm fairly sure there's 20 different amino acids and hence 20 different types of tRNA molecule. So each tRNA molecule will hold an amino acid specific to that tRNA molecule. It picks it up because it's being mixed together in the cytoplasm. Like mixing a solvent.

[OriginallyRegal]

IF-2 refers to initiation factor 2, there are 20 different amino acids but about 64 different codons-- including (1 initiation codon and 3 termination codons) the rest of the amino acids have either 2 or 3 different codons that produce them. also tRNA uses codon sites to "pick up" specific amino acids and then carry it to the EPA sites of the complexed ribosomes (70S Ribosome)

[OriginallyRegal]

thanks someone pointed out some stuff in my statement: 64 different codons, about 51 (i think) prokaryotic tRNA's, and 18 amino acids- each off the stop codons have proteins look alike (RF-1 and RF-2): you should also look up i guess it would be called "codon wobble" if you're really trying to learn all of this stuff

[WhichDoctor1]

Is it just me or is it totally freaky to think there are all these little whatsits working away in every sell like little robots. I listened to a episode of the bbc's "Material World" about these thing the other day but I couldn't really imagine what they would be like. This is way stranger than I had thought.

[MagicQuinn]

It's just you.... lol jk

[Thawtheant]

it isnt just u ..

[shevegen]

I think the animation is excellent, however it seems to have simplified a bit. How does the mRNA "reach" the IF in the ribosome? Is it carried? (I would assume so) But anyway, it should be part of this animation. Also, the environment looks a bit odd. I am aware that so tiny structures behave differently than our "big world" but still it would be nice to adjust a picture to the real complexity. Also, the" winking parts" were fishing proteins for Translat.Factors?

9 out of 10 points on my scala

[jaapsneep]

shouldnt have made it with such colors and moving arms or stuff its really confusing, looks like some ghostbusters ghost trying to eat a carrot

[steevmac]

Lots of people asked "how does it do this all on its own?".

Well, chemicals do stuff on their own, based on chemical reactions, bonds & charges. Life is based on chemical reactions which follow *relatively* simple laws & patterns.

If you don't understand how it happens, research "valency", "acids & bases", "oxydation & reduction", "lone pairs", "covalent & ionic bonds", "crystalline structures" OR buy an organic chemistry textbook, followed by a biochemistry textbook. The answers are there.

[zastor99991]

@steevmac hehehehe of course, but after all, you must ask your self: ''How works oxydation and reduction, how protein synthesis works, how is the DNA and RNA so perfectly based? .... how, how how??? there is a milion of how, but there is only one answer... Allah s.w.t. perfectly created the whole world :) elhamdulilah for being muslims, because Kur'an is perfectly match with science. Read about it...

[steevmac]

@zastor99991 You can't look at protein synthesis and DNA or RNA first. You have to discover the underlying principles behind them all. If you look at the whole picture too early, the human mind runs away with itself.

In addition, why is it that complex DNA needs an answer, but a supposedly even MORE complex God-designer wriggles out of an explanation? How do you explain Allah's existence? Think about that.

I will do a video soon about the Qur'an's supposed scientific knowledge.

[TenaciousC58]

@zastor99991 LOL, NO wrong answer

[zastor99991]

@TenaciousC58 whatever, I'm proud to be a muslim :) elhamdulilah. and I'm telling you to read. just read. it isn't so hard. you just take a book and educate yourself :)))

[cbernier3]

@zastor99991 you are an idiot. The answer is beyond your understanding. You don't understand chemistry, evolution, quantum physics, or the other things. Allah does not exist.

[zastor99991]

@cbernier3 I'm student of all of this what you have told: bio-chemistry, evolution, bio-physics, zoology, etc. And everything told me how perfect Kur'an is. You're not gonna resolved any problem by calling me ''an idiot''. Actually, you can speak what ever you want, because that would not change the facts. THE FACT IS THAT KUR'AN IS PERFECT, and there is nothing that you can do about it. My advice: read a lot. Don't be conservative.

[Keftes89]

@zastor99991 Wrong just wrong... if you think the Kur'an matches with science and is perfect, you are brainwashed. Being proud to be muslim is fine, but spreading lies is not... I think you should pick up a book; not the Kur'an, a different one....

[PakFa1988]

@zastor99991 I totally believe in what u r saying & read my comments about this video here on youtube This is why I believe that the believers must become Something Big someday becouse they don't have a narrow mind & say all of this is coincidence. No there is a role 4 everything god created & we believers must study this to see how god is so significant while they only study this for money or fame which one u believe will acquire more knowledge this is why the 1st world in Quran was read.

[IMAHMS]

@steevmac makes you wonder.. if our so called self-awareness or consiousness.. our purposfull movement, are nothing but a sum of or a more complex form of the same thing type of things here.. chemical, mechanical, purpose-like

[steevmac]

@IMAHMS Indeed, you are right, it does make you wonder. The next step after wondering though, is to go & study the subject. Our personal incredulity is a very poor judge of what is true & what isn't. There are so many times when our brains, eyes and ears cannot grasp a concept, yet empirical measurements & rationality are the most reliable ways of bearing out the truth. Magic can never be written off, but it is unfalsifiable, superfluous to our understanding & detrimental to our sanity.

[IMAHMS]

@steevmac I think our actions are decided by our brain through an automated series of interactions of neurons that recieve inputs (including the situation & the mood we are in, & the past experiences), process it through a network of neuron's connections (similar to computer alogrithm), lead to firing of neurons that results in a responce (which could be saying something, give a facial expression, feel afraid..ect). we become consciously aware of our responce, gives us the illusion of free-will

[Jimisonjons]

Wow it's so coordinated!

[zastor99991]

@Jimisonjons did you ask yourself: "Who is The Coordinator?''

[caryl101]

thanks.. i really need a video to reenact it on our biology class

[Raghav91]

thanks.. This is gonna help me score better.. thanks!!

[kawkazianaziangrl]

things like this prove evolution is for monkeys :) i'll stick w/ knowing we were created =)

[bob9758]

it really doesnt

[Suki40330]

Yes, it really does.

[bob9758]

how

[wabawoba]

Complexity = creator?

God's brain structure must be *much* more complex than this ribosome for him to come up with such a complicated idea.

God himself is the ultimate complex being. I wonder if he was created?... hmmm...

[pedroalcanta]

So, as your brain has suffered from an overflow and you can't understand such complex things exist, you need a creator? poor you, do you also believe that rain comes from god crying? how cute

[anthonyo99]

How do these things move, and how do they find each other?

[holymion]

Chemical signs dude !

[PilateLite]

This is the best demonstration of ribosomes that I have ever seen. It even managed to amaze me more than I already was by the seemingly magical process of protein transcription. This is truly a glimpse into one of the primordial "engines of creation"

[Rusfbm]

I'm glad to see the highest perfomance video resolution!

[ytrabbat]

Very well done. Thank you for posting this.

[RabidApe]

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