Animation: The Central Dogma

[sujitdada1]

Bumba my beloved brother you're pride of the world. wish you all the best. kaludada

[nejiastig]

Coming soon, Enzyme Battleships: The Cell Wars

[jhamien920]

Wow. I'll be watching more videos here in this channel.

[moomeowdogg]

Some sick beats dropping in this video. When RNA Polymerase II does its thing, that's some next level shit right there.

[mirzairfan88]

dis video helped me fool my 4 yr old nephew into sum Japanese cartoon..... he even luved d music... n at d end we both were dancing

[rerun62696]

What is the name of the second song?? I love it so much!

7:13, kayy?

[rerun62696]

What is the name of the second song?? I love it so much!

[rerun62696]

Please tell me the song!! I'm begging! :-/

[rerun62696]

Wow thank you so much I was confused about transcription and translation, but now I really get it! It looked cool and had great music, so I was REALLY interested!! Thanks again.

P.S. What were the songs?

[MrTeaegg]

like star wars

[oneworldfamily]

Is this not simply fuelling the appalling misconception that living organisms are basically all machines? Nature should know better than this.

[fugginahole]

@oneworldfamily seriously? Wha!! This is the best video on central dogma there is!!! I It is so precise and easy for someone like me to understand, like a machine in its function: it is!

[tparanjpe45]

As a bio major, this video's so helpful to put things into perspective. Not to mention, the animation and the music are fantastic!

[prof3f]

O DOGMA CENTRAL

Da informação genômica à síntese protéica

A partir da informação codificada no DNA genômico, proteínas são produzidas.

Vamos entrar no corpo humano para descobrir como as proteínas são produzidas.

Dentro do vaso. Um linfócito faz seu percurso. Vamos entrar.

Organelas e os núcleos são vistos. Entrando no núcleo através do poro nuclear.

Cromossomos estão localizados dentro do núcleo. O DNA genômico liga-se a histonas.

O DNA genômico é dobrado várias vezes.

[ukvariola]

I love the robot/mechanic/spaceship stylisation. I am so used to see everything depicted as blobs, or erroneous shapes that this made a refreshing change.

I also really like how the interactions between the proteins are shows, with docking, hooking on etc rather than just passively joining up.

And I am still chuckling at RNAP 2 :-)

[urnotalone]

i really started laughing out loud when RNAP2 arrived =)

[dragonsrcool12345]

That was in a word amazing and really helped in the understanding of the processes and there place in the bigger picture :) thanks very much ^_^

[kalebird]

BADASS! what are the names of the songs?!?!?

[lxpk]

Awesome video and the high-tech stylization is weird but it is clear how things work with each other. Watch this on a Mac after pressing command-option-control 8 and the colors invert making everything glow like Tron! Also, this was made in Japan, which explains why everything is super futuristic and mecha-looking.

[lxpk]

Awesome video and the high-tech stylization is weird but it is clear how things work with each other. Watch this on a Mac after pressing command-option-control 8 and the colors invert making everything glow like Tron!

[sniffMaGusset]

The song at 4.00 needs some 303! Aciiiiid!

[Clockowl]

Why didn't you use the CC feature? Other than that, good movie. :)

[Mettlerfreund]

good work.

[yaHARmeMATEY]

didnt have a clue wtf just happend but it looked bad ass

[koainua]

In the (nano-sized) big picture, this is an amazing video. Why the animators chose to utilize robotically mechanized looking agents in lieu of a more biologically accurate portrayal is perplexing and disappointing. Other than that, what an amazing video!

[museumoftechno]

I don't like the subtitle (6:30) "Once the necessary information is transcribed... RNA polymerase II leaves DNA" because carries a flavour of purpose: it seems to suggest polymerase is sent intentionally to do a task, whereas I thought (and what amazes me is) that all this machinery operates by molecules bumping randomly into each other?

[smartse1]

@museumoftechno

I've never managed to get my head around how that actually works though!

[brazilian777able]

GOD'S CREATION. HE is soo perfect!

[thebighead01]

just beautiful. a whole universe in one cell. absolutely fantastic. just why no voice over? putting in subs forced my eyes to look away from the brilliant visuals half the time.

[skypedog5]

I am trying to understand genomics I am not really a 'science guy' can anybody recommend a good starting text?

[gaboon01]

@skypedog5 Try, "Genome: The Autobiography of a Species in 23 Chapters by Matt Ridley"

[skypedog5]

@gaboon01 Hey Thanks! thats great my Library has it and it is on the way. Cheers

[ianrusselluk]

It would be interesting to evaluate its appeal and effectiveness with different target age groups. I think I can guess the outcome... And I like the absence of spoken information! I find it easier to focus when I don't simultaneously have to process information coming into my brain through a separate audio channel! Such concise text is quite OK. Anyone old enough to understand this is old enough to read.

[wasdom01]

I imagine that this is what 'TRON Legacy' would have looked like if it had ben an infotainment picture...that didn't suck! ;) Very interesting and unique style with a thumping soundtrack. Great stuff guys.

[Stonehawk]

It's a shame that they took to calling this a "dogma". Dogma has a -huge- stigma associated with it. Personally, it's repulsive. Modern culture has created countless memory associations between "dogma" and being "incapable of accepting evidence" and "accepting on faith alone". Regardless of what the term's origin was, humanity has developed an allergic reaction, and I think it'd be better for everyone if we adopted a new term.

[ukvariola]

@Stonehawk

The Central Dogma is what it is called, they are core principles, not disputed, and widely accepted.

Modern culture can do what it likes, but it plays no part in molecular biology IMO. If people are stupid enough to be turned off by one word then they don't have the brains to appreciate what goes on at that level anyway.

[2Dudelsack2]

great

[yexela]

nice video, but the problem is that it clearly violates the second law of thermodynamics (when all these nucleotides rush into their places).

[3Gyro]

@yexela Trying to show what actually happens would be a gigantic clusterfuck. Nobody would be able to see anything.

[3Gyro]

@yexela Trying to show what actually happens would be a gigantic clusterfuck. Nobody would be able to see anything.

[CamW30]

My god, they look like designed machines (LOL).

[neogodshadowcat]

pretty rad for a vid on biological process

[xdopiex]

if you show this to anyone who is beginning learning transcription/translation, theyre going to think that cells operate with mini spaceships

[museumoftechno]

@xdopiex I was going to ask to what extent the shape of the transcription factors in the video reflected their molecular composition, until I saw "RNA Polymerase" written on the side of some RNA Polymerase. Mind you, perhaps RNA Polymerase DOES have the words "RNA Polymerase" written on it, as a joke by God.

[violetpretty777]

@xdopiex , you mean they DON'T? XD

[Sincee1809]

awesome

[manolotube666]

Reality beats Sci-fi...

[mcmurder3]

Great work tho... :D

[mcmurder3]

this thing is so epic for only a molecular biology dogma xD