Crawling Neutrophil Chasing a Bacterium

[JadeTubeXx]

it has EYES D:

[mphello]

This video is offensive to bacteria.

[hinotf]

Супер! Молодец, что догнал.

[phytrone]

Macrophage uses ROS. It's super effective!

[crisphate95]

I got here from a TF2 video.

[iarespectreful]

hypertonic solution?

[metallhead94]

@iarespectreful Is it not isotonic?

[muna323]

سبحآنك يآ آآآآآآآآآ ربي مآ أعظمك = (( 

[ercwst]

Om Nom Nom Nom

[Tiagoliquid]

RIP Bacteria! :'(

[AdjebennShredder]

\,,/ ! ! !

[FernandaSayurii]

Chupa bacteria!! hsuahsuah

[uzickemo]

este es hermoso

[codadrums]

ahaha mrhappyDJfish i did the same fuckin thing ahaha

[ipwnnubzwithforce]

@codadrums me too da fuck

[Rachpin]

This is not a neutrophil, it has scourges!

[nicodgusanito2012]

Run Forest Run

[No1overhere]

Fuck yeah!! now i'm O.K. :D

[RhenoRhenorum]

1- Open Benny Hill Theme and play it

2- Play and watch this video

3- Enjoy it

[metadonalife]

TOMAAAAAAAAAAAAAAA

[jordede]

NNT

[terrorista31]

That's why our body need to rest enough time so our internal Pacman can work better

[MrDJHappyFace]

I went from ray charles, to something about a fucking zebra fish to this.

wtf.

[Dividing9]

I dont know about you guys but this reminds me of GTA 1 and 2 on the playstation 1, theres just soemthing about that top down view and the chasing.

[Nifflehim]

"Me come wachoooo" jajajaja

[vk45de]

2 of them got away... for now

[Draguinclan]

aw, you got caught o well

[BetterJS]

KEEP TUMBLING! HE'S RIGHT BEHIND YOU!

[YtzikTV]

yummy yummy... was so delicious! :D

[canefan17]

What took the neutrophil so long to eat it?

[jakubgt1]

@canefan17

The diplococcus bacterium had a flagella attached to its axial filament. This allows the cell to become motile and exhibit negative taxis. The leukocyte senses the bacterium, but bacteria are generally faster than eucaryotic cells. As soon as the bacterium becomes 'lost' or 'trapped' it undergoes phagocytosis from the leukocyte. Hope that helped!

[canefan17]

@jakubgt1

Fascinating stuff, thanks.

I would pay money to see a spirochete under siege!!

Borrelia preferably :D

[irateyourvideo2]

@jakubgt1 haha, you said "phagocytosis"

[CHEVYedsf]

@canefan17 It was chasing it.

[canefan17]

Where does neutrophil go to get rid of bacteria - into spleen or lymph?

[gshank80]

pacman

[zetalore]

wow

[thanger2]

Feels like i'm watching gameplay on SPORE phase 1

[peppermintfreak1]

Thumbs up for chemotactic lock-on!!!

[Zombiebabe138]

Old movies of bacteria, human cells and slime moulds are probably my favourtie thing to come out of the 1950's. So beautiful and complex, its hard to beleive this technology existed so long ago.

[Kronenschule]

Schau doch mal bei Facebook unter " Schmerzfrei in 5 Minuten" vorbei, eine geniale Sache, hilft wirklich.

[teewoods]

All white people looked up in cells where they belong lol

[raztarak]

Thumbs up is republic poly brought u here

[sorafreak93]

funny...its like seeing a cat run away from a dog lol

[moresbiful]

how many of these neutrophiles are in a steak?

[CHEVYedsf]

@moresbiful Depends. They're always present in the blood so if you eat your steak bloody than chances are you've eaten neutrophils.

[maru93th]

Thanks to that we can survive! Excellent video

[ZeroFjernsynet]

Wow, I for some reason, feel bad about that poor little bacteria cell.

[thesilentazn]

GET IN MA BELLY!!!

[flasher555]

@thesilentazn

ROFL, good one.

[nazymani]

The human body works in simple ways but yet it's still too complex for man to understand. Science has nothing to do with racism it is purely made of facts not opinion. It is what it is don't turn it into some crap that makes it look like something else. Only people who don't see the beauty of life will die regretting they had a few more years of life to understand....

[mphello]

Conservaturds love pitting whites against blacks by stealing their money through taxes and a fascist legal system that forces people to choose between freedom vs giving up all their savings to a lawyer. Then, when blacks and whites fight, conservaturds love blaming liberals and radicals for it.

Vote Green! Only Greens, Socialists, and Communists are true patriotic American heroes.

[hardlybreath]

PACMAN!!!!!!!!!

[whonow09]

Run, bacteria, run!

[TheEirikMan]

The only way to stop racism is to kill ALL white blood-cells!

[revenger20012]

@TheEirikMan there's an easy way to do that

go fuck some whores till u get AIDS

then all your white blood cells will be dead

[CHEVYedsf]

@TheEirikMan Hahaha and succumb to terminal disease in the process. So if you want to die, than please, eliminate your white blood cells.

[ciaobellakate]

The 50s were racist times.

[Patsa2001]

purely a chemical response

[BlackandBlueMage]

wouldn't this go better with a little matrix chase music?

[SuperL473]

This video would be epic if it had more Heavy Weapons Guy in it.

[Sonicku]

Woa, this thing knows what is chacing and chooses to kill one of the two bacteria. And have you seen the chased bacterium, its trying to evade, but the other one does not. These things must has consciousness and free will!!!

[generalflood]

flagged 12 times for intense racism

[badassnewbie]

Wow I can't believe you political activists are tainting a biological wonder with our irrelevant racial views.

This is only a phagocytic cell chasing a motile bacterium, done under a negative stain with low resolution (so the smaller particle appears black instead of clear). Anyone who sees any racism in this needs to go take microbiology and get some sense into their heads.

[dabigjokeoftheday]

if its eating bacteria...does it poop it back out? where does that go?

[KinStrategy]

@dabigjokeoftheday It can either be released as a digested substance, to be excreted by the body later. Or, it can be left in the cell as a residual body.

[delta024]

That video made my day.. I kinda expected the neutrophil to be faster but I guess cytoplasmic streaming of a giant cell that can phagotize anything, might cause it to be slightly slower.. Maybe if we genetically reengineer this thing with a couple flagella's we can get a unstoppable machine.

[EliteDoomer]

@delta024 a couple flagella would just indent it's side slightly, too massive :)

[CHEVYedsf]

@delta024 The neutrophils are actually only for small particle phagocytosis. The monocytes are for large cell phagocytosis. Neutrophils are medium sized cells.

[delta024]

That video made my day.. LoL Those Neutrophil is like a tank...

[Annie1962]

@lostdreamz901 repeat that with a mouthful of crackers.. I dare ya.

[hivecluster5]

Immune System WIN!

[ale9z]

sex and violence

[ScramUK]

Is this in real time? Looks like he missed one.

[RRoo13]

That is SO cool!

[aklsjfawfiow]

Notice, how even at the microscopic level, the black ones always are the infection and get chased down by the whites. :D

[Shikamaru1212]

Why didn't it death

[Elite244]

It smells a trail, like a dog. Arf.

[tabletopphoto]

For something that doesn't have a nervous system, how does it identify, stalk, and hunt down its prey?

[adasdadinator]

it just has really nice stimulis-ressponse

[tabletopphoto]

response? It was stalking and chasing down it's prey like a predatory animal. I don't know any better, but I would say it holds some level of intelligence.

[Rnexen]

@tabletopphoto

lrn2 chemotaxis

[JohnRiemannSoong]

it's called a cytoskeleton

you should study biochem =)

[JohnRiemannSoong]

don't forget bacteria have capsules that extend beyond the cell membrane; it's conceivable that it works by touch

[tabletopphoto]

You could say the same for us. We are just robots that work on chemical impulses and programmed responses........ I personally think it is more than just that.

[JohnRiemannSoong]

very dynamic systems can arise from very simple sets of rules. have you tried Conway's Game of Life?

[tabletopphoto]

and?

[Razersun]

seems gay

[FaMyLi]

Oh yea? ;) Be happy that you have those little guys or else you wouldn't live for long.

[Razersun]

Wow.  Gay comment.

[DAJ01]

People are commenting about racism, but all I see is a white blood cell suppressing a blackteria...

...er, wait, let me try that again.

[alihaq92]

@DAJ01

Bacteria was stained thats why appearing black :)

when neutrophil goes mad it even attack red blood cells :)

[Honeytrip420]

@DAJ01 HAHAHAHHAHAHAHAHAHAHA I like your comment

[go2ec4]

@DAJ01 white blood cells aren't really white they are called white because they aren't red !,

[vk45de]

@go2ec4 Just thumbs him down. Don't feed the trolls.

[PresidentLucario]

lol the bacteria look like they are having a nervous breakdown even though they don't even have nerves

[Plopkap]

Can someone add the Benny Hill theme to this?

Pwetty pwease.

[GunterYang]

watch?v=SlSUVqvrtxo

You'll have to manually combine that with the youtube part. Brilliant suggestion btw.

[Whitesoxcesarmexico]

Damn, that bacteria got OWNED!

[jattboypunjabi]

Damn nature you scary.

[nlty2000]

marvellous vid. i wonder how those bacteria move.

[AvatarofMasks]

Bacteria can move with flagella (a few long whip-like protein structures), by flexing/spinning (not the case here, I don't think), or by constantly extending and withdrawing fimbriae (long, stiffer protein structures), so that they bounce off of fluid like a pogo stick. There may be more methods, but these are more common.

[p0o7]

I think they use cilia.. if I remember my grade 11 biology well enough. A whole bunch of tiny little hair-like things that they whip to move.

[AnubisMxD]

i think cilia are used for a different purppouse... they are used for "sweepping" and cleaning for example... the respiratory tract and flagella are used for making the cell to move (like in this case)... im sorry if my english isn't good enouht...

[Shenten]

Either through ciliary or flagellar movement, I'd say. The microscopy doesn't really show any formations, only the black body... You can usually see something as fine as cilia or flagella through special staining...

[iCookie1]

How does the white blood cell sense where the bacteria is??

The whole chase seems quite intelligent, both on the bacterias part and on the white blood cells part...

[AvatarofMasks]

Macrophages have proteins on their surface, called Pattern Recognition Receptors, that sense the presence of certain things that are not a part of the human body (e.g. double-stranded RNA, Mannose sugars on cell coats, Non-methylated DNA, or lipopolysaccharides). Once the initial "feel" occurs, the Macrophage will keep heading towards the bacteria, sensing it from momentary contact and disturbances in the fluid, neither of which are visible at this magnification.

[paolo27th]

Interesting stuff.

[Meatfortoeat]

@iCookie1 What I'd imagine is that they detect the elecrtical field, realize that it is a bacterium, and then follow the field.

[Grysham]

@Meatfortoeat

Close. They detect a chemical emmited by the bacteria

[trini0015]

yooooooooooo!!!! o  ---

[TheCityDreamer]

HOLYFUCKINGSHIT.

I'm going to have trouble sleeping... Dx

[Reichu]

I need moar liek this.

[CaCuS7]

me too

[spamdude060]

0:20 bacteria own3d

[interwoven222]

holy shat, that is awesome, did ya see how the netrophil went 2 diff ways when it was near 2 diff bacterium, I wonder how it sensed the other, and differentiated from the other micro-organisms, also what decided it to run after one and not the other?

[exracon]

the sensing involves exogenous chemoattractants such as FMLP binding to receptors of the neutrophil/leukocyte

[maxim3L]

keyboard cat viewer: did the bacteria died?

[Kill3rTcell]

@maxim3L - Oh yeah. Om nom nom.

[cyfer911]

NOOOOOOOOOOOOOOOOOO!

[MrsSabrinaCullen57]

is that real rite enough?

[Catchetat]

so cute =x

[NoJake]

Damn, look at that thing run! And all in vain...

[nicocapote]

i think that need some benny hill music LOL.

[shantibloo]

tada dadda!

[SomeThingGoneWrong1]

bacteria:run run run

other thing:YOU ARE NOT WELCOME HERE!

[Taojac]

yaaay go fagocites

[SerenaiXdemon]

GET IT, GET IT, GET IT.

[CUCbK0]

Будет знать тварь, как в организм попадать

[oscarstuard]

haha muere diplococo jojo

[AlmostImportant13]

Run Bacteria You Can Still Make It!!!

[Lizaboricua21]

your comment made my day!!!! JAJAJAJJA

[tobathome]

you can run but you cant hide. actually how is the bacterium moveing?

[emceha]

bitch please

if you want answer, type "How Does Bacteria Move" in google not in youtube

[spamdude060]

w/ a flagella u dumbass, go back 2 junior high @tobathome!!!!

[NekoTonegawa]

Queee boniiiiiitooooooo!!!!

[piturrin0]

:o nunca habia visto un video de una fagocitosis :O me sorprendio excelente video

[masterjoe42]

our histo prof showed us this vid with the "jaws" theme in the background... awesome :D

[jenny98076]

I wish they did it longer. This really is interesting. Before, I never really cared much about what happened in our body but seeing this video amazed me. =]

[Shigren]

YES!!! Get that bacterium bitch! GET SOME!!! GET SOME!!! YEAAAAAAAAAAAAAAH!

[xxMrBaldyxx]

NEUTROPHIL 1 -- BACTERIA 0

[AurynThePaladin]

As a liberal I am offended by this video. The bacteria is obviously the minority and on top of that it's black. Then the big powerful WHITE blood cell comes along and strikes at the poor bacteria. Unable to defend itself the bacteria succumbs to whitey. We need to make a change. Wake up America! You say there is nothing 'you' can do, well that just isn't true. Simply stop washing your hands and taking showers regularly, then these poor bacteria may have a fighting chance.

[vajrayogi]

Pretty sure Auryn was speaking with tongue in cheek msgg49 :).

[FlashBangGrenades]

Umm i`m pretty sure that was a joke -.-

[NartSaga]

some people need to get a sense of humor :)

[Izrhyscboi]

@AurynThePaladin Yeah and let us all die...

[EviICookie]

@AurynThePaladin Wont not washing hands or showering will simply give our white blood cells more blackteria to terrorize? They'll simply become even better at their oppression.

[rmleider]

@AurynThePaladin

Good point, if only we could wash our hands of all the non-whites. You're a moron.

[predator810]

Is this a view from a microscope?

[ichbineintoober]

White cells are racist.

[shevegen]

But a bacterial cell does not belong to the race "white cell".

It is an alien. And can you be a racist against aliens?

[Hyshinara]

how about ILLEGAL aliens? :o

hahaha XD

[electronixtar]

amazing!

[boritchka]

I keep trying to turn the volume up on this to no avail

[Driven000009]

Yeah I noticed they forgot to add Yakety Sax to the video.

[moeistheirleader]

holy fuck. Is that happening inside me?

[Veteran4Peace]

Science is AWESOME.

[stfudonnie]

OM NOM NOM

hi reddit

[NukeMoose420]

First pacman game!

[ravenrriddle]

you mean I have a permanent pac man game going on INSIDE ME?

OMG THANK YOU, SCIENCE!

[fr3d420]

I imagine there are over 9000 of these.

[Arctic122]

how this lil shit know where bacteria is

[yumsalad]

the ones that are not like the others i suppose

[psychologicalshock]

Chemical signaling I think.

[DiggingMyOwnGrave2]

It sure looks like that white blood cell is relentlessly

"taking out" the bacteria, & everybody else is just trying

to get out of the way...

but, I've never seen this and find it incredible, however

it operates.

[Avidity]

OM nom nom nom!

[Morrakiu]

that bacteria got pwned

[vpxg0tryc]

bacteria fail

[ch33s3m0ng3r]

Basically, the white blood cell is chasing the bacteria. It uses an "INTEGRAL CONTROLLER" to track the bacteria's path error-free.

[Scrummmy]

I'm actually surprised at how the bacteria can sense that the neutrophil is there.

[psychologicalshock]

It might not be that it senses it but that other cells are alerting it. That is to say it's like a hive mind.

[mikkitiny]

in fact, amazing vid. it's called hemotaxis, precise mechanisms are unknown but the illusion is the macrophage behaves as an intelligent entity! lol.!

[vegetish]

What are all those round balls?