Pedigree Analysis 1: How to solve a genetic pedigree No. 1

[pur33z]

I've used this for the past 2 years.. thanks bro helped a lot.

[Heychick13]

THANK YOU!! that helped me understand pedigree charts. i searched for videos cause i'm scared of my science teacher.

[Soccercardman7]

so if dad has XAY and the mom is XaXa then how would this work?

[andrewdouch]

@Soccercardman7 Then all their daughters would be XAXa and all their sons would be XaY

[baidooish]

u are awesome i was studying for my MCAT and seeing ur video made my day

[Gerbilinator]

YouTube-My biology class

[TheBabgi]

you made my life a hell of a lot easier now, greatly appreciate it!

[simin19100]

Thanks so much.

[MFG762]

He gets tickled at 1:10 lol

[TheFilren]

thanks!

[lalalamonique]

Awesome video!

[cwolfff100]

Hey, great job with this video. I understood your explanation a lot better than my Biology Professors.

[EmperorFaris]

Thanks for the help

[thinkgreenlovepurple]

I watched this a year ago before my exams. And here I am again. Thanks so much!

[isa220590]

ur the best !!

[ComicBookGeek421]

I have a biology test tomorrow and I've been having a lot of trouble with pedigree's this video helped a lot though. Thanks! :)

[BlueLuvsGreen27]

I haven't even gotten this far in my class, and I got it SO QUICKLY! thanks xD

[305tzar]

I love science so much. I understood this so quickly. Thank you. But people dont panic, just ram it and keep on trying til you get it! It doesn't matter when you get it, all that really matters is for you to get it

[Alydeexo]

This helped me so much! thankyou

[ethi17]

This is one of the best explanations of pedigree analysis that I have ever seen. Thank you so much!

[ASSHOLELA]

because John fathered 2 children with the w/W genotype, Mary suspects that he is the one who gave the w gene to their child.

How do you calculate the probability than John, as opposed to Mary, gave the child the w gene?

The tricky part is all their genotypes John, Susan and Mary are unknown,can be W/ W or w/W , definately not w/w because they are not white haired! but it is supposed that genetic counsellors can work out the probability empiracally. How do you do this?

[andrewdouch]

@ASSHOLELA - I'm not sure ... It's tricky, because it's possible that John is Ww and both women are WW, but it's also possible that both women are Ww and John is WW. It's even possible that all three are Ww! Each of them (before having kids) had the same chance of being Ww. So all we can deduce now (I think) is that the chance of Mary being a carrier, is equal to the chance that Susan is a carrier, and John's chance of being a carrier is double (since he has had two babies with a w allele).

[ASSHOLELA]

hey andrew,

I had a problem in homework:

Out of every 10 people in country X, 1 people has the white hair gene w (W= normal hair) . white hair is a homozygous recessive, people will only get white hair if their genotype is w/w.

John and Mary had a child which was found to be a carrier of white hair gene, w/W. It was also known that John had a child with another partner Susan,  the child also with the w/W genotype.

[MrSushil4060]

Very well explained

[ladietay1]

Thanks for this my teacher cannot teach this worth of shit .

[cutiepwincessangel]

Thank you soo much..this was helpful

[andrewdouch]

you are welcome :)

[lamichhanesuyog]

thank you very much.

[alienshinubie]

Very well done

[girlclasse]

I appreciate your work here, but I have to admit that I'm quite confused with pedigrees after watching this.

[andrewdouch]

@girlclasse - Pedigree analysis is complex - there's no doubt about that... and I think most people find it challenging. So don't feel too bad about that. There are a few more examples on here, you may find that if you watch each several times, it will start to seem less confusing.

[theoldrevolution]

@girlclasse I'm taking my exam today for introductory genetics and this has helped far more than the class notes

[andrewdouch]

@SuicideWaffle New episodes will be coming your way very soon :D 

[LoLInstinct]

It would be unthinkable for most diseases that two people from the same family could randomly meet two other people with the same recessive mutation. It's simple statistics.

[andrewdouch]

@LoLInstinct Once again - thank you for your comments. But it's important not to make unfounded assumptions. There is nothing given in this example to suggest that the "trait" being discussed is a "disease". For all we know it could be a common recessive phenotypic trait such as 'attached earlobes' or Rh- blood. It's not "unthinkable" in the least that two people from the same family with Rh- blood could randomly meet two other people who are carriers of that same allele!

[LoLInstinct]

This man clearly doesn't know What hr is tælling about. This pedegree is almost certainly autosomal dominant inheritance with reduced penetrance. He could easily have pulled out x linked patterns just by seeing the father to son transmission in the first generation.

[andrewdouch]

@LoLInstinct Thanks for your input (although I am fairly confident that I do know what I'm talking about lol). It is much more likely to be autosomal recessive than 'autosomal dominant with reduced penetrance' lol. And regarding your second comment (also wrong), you cannot "pull out X-linked patterns" based on the relationship of I-2 and II-5 as you suggest. If it was X-linked, I-1 could have been a carrier which would have made it mother-to-son transmission.

[ugasziz]

helpful

[princejackie]

he explains it better than my teacher!

[SkinnyWhiteLoser]

i want to make sweet love to him

[thecore1331]

thanks, really helped

[kerry1450]

brilliantly explained thankyou.

[sumanasathar]

really gud...well xplained...thanks a lotttt



[brennajess]

can i have yo numba?

[Truth987Seeker]

0:01

[Vincenthusky]

yo I got 3 x chromosomes

[tonychet2s]

@Vincenthusky trisomic down syndrome noob!

[Vincenthusky]

this is really confusing

[elf3l1f]

Thank you so much for saving me on pedigree question for the exam. My professor failed at explaining this. You excelled!

[dielliboy]

so simply explained thank you so much



[dexxunknownsoldier]

Dudem this helped me soooooooooo much. Thank you, for real.

[ruewashe]

you are amazing! thanks

[jcguerrero1985]

very good....congratulations...



[shakiwhat16]

Thanks for working this with detail. I have an exam tomorrow in Human Genetics, this helped me out a bunch. Thanks again!

[aprilgita89]

thank you for so thoroughly explaining something many of my, ahem, UC professors are negligent to do.  Rock on, post more! (Genetics-ish, I mean)

[alhammadi767]

thank you ,,

[dannyreijo]

1:14 BIOLOGY IS SO EXCITING!!

[cceessaarr234]

Haha, I knew the answer @ 6:30. Ha, Im smarter than you all!!! XD XDDD

[mansanpreet]

very helpful....



[AllDayRippa]

cool :)

[tonyizhurr]

You sound like that one guy from funny people. the guy with the accent.

[HDRCX550VE]

HSC Biology trial tomorrow, I might just be saved! :D

[thephaze3]

@HDRCX550VE Haha me too. =)

[skf303]

genius. I feel stupid because in my class we're supposed to just see it but if you just do each then you can't lose.

[hankwasher123]

glad to see that someone has such a passion for teaching and enjoys it as much as you do. thank you for posting this on youtube.

[kb8277]

Amazing! Thank you so much!

[geneticthrower]

Thank you!

[jamilbigj]

Not only do you explain it clearly but also you show the enthusiasm on teaching it. If only every teacher was like you.

[OurAlienFriends]

thanks bro

[thinkgreenlovepurple]

thank you so much! my biology exam is tomorrow!

[LindseyLeeAnn]

Such an awesome explanation - didn't go too fast, and you kept it simple without making it to general or juvenile. Thanks so much! You're awesome!

[LindseyLeeAnn]

Such an awesome explanation - didn't go too fast, and you kept it simple without making it to general or juvenile. Thanks so much! You're awesome!

[reeness09]

Thank you, good sir!

[KitSanderson]

This Douch knows what he talking about!

[blablanoob11]

Thank you very much this helped me with my science exam

[riteshlogin]

turn on the subtitles it's hilarious LOL

[SweetlyEmily]

thanks so much for making it easier to understand!!!!

[meltingskin]

Gracias!

[serine456]

Same here. I understood this better in this short video than I did reading the same two pages over and over again

[du4316]

i learned more in this 9 minutes and 13 seconds then i did in my 1.5 hour lecture today

[EmmaRoseM33]

I have a genetics exam in the morning. . . thanks for that! Big help.

[skunk1112003]

OMG THAT WAS AWESOME ! THANKS SO MUCH!

[gooel]

That was very helpful! Thank you very much for your time C:

[pur33z]

Very well explained, you are a great teacher, amazing accent! :P

[ngarcia610]

Awesome!

[funkymonkeybabywoot]

is the Y on the man (XY) an a or A?

[arsenal1416]

I seriously love this Australian person

[redangel88]

this is awesome!

[mccarror]

thank you! you explained that so well!

[1223Melo]

You are awesome dude.

[anthony9809]

impresive

[gwjib04]

you explain this so well. u always clear up places that cause hangups

[sinndylovex]

this save smy life ike fo reallll

[thisislifein00]

You are a god, thank you

[ADLSTODEO]

@thisislifein00 Shutup, His human Not god u wuss.

[birdman1265]

Thank you so much!

[langleybro]

thanx so much i wish you were my teacher this helped a lot

[kieranhan1]

Wow! I am a primary school teacher with no Biology experience whatsoever... and I followed (and even understood!) your explanation

[happy321hh]

i hate this shit lesson

[900bigd]

Great help thanks! But wow u must get ripped on by ur students lmao

[blindwillow3]

its really really helpful!!! u r a awesome teacher!! thanx!

[zainiali89]

This was very helpful. I have exams on this and I was really stuck. Thanks ever soo much for explaining it all.

[katiejimenez7792]

This was so helpful ! I totally get it now ! Thank you so much!

[crabypaty4]

thank you!!!!!!! thanks so much!i passed my exams cause of this vid!ty for this informative video:)

[mb0185646]

This was 5 kinds of amazing. I have a genetics final tomorrow and now I'm going to dominate.

[Jackfromcs]

I was pulling my hair out trying to figure this out on my own - thanks for the great video

[Musicalmelody7]

THANK YOU!! Yes. Amen! Thank God for teachers on Youtube!

[alqamar2009]

thans!!



[nakiki235]

Thank you so much.

[valsera246]

God Bless you! You just saved me! Thank you very much for this informative video:)

[TMillenia]

ohh so basically you can assume anything for the people not related to the family in order to make it work for their offsprings?

[alqamar2009]

@TMillenia yes, but only if it explains what you see in the pedigree

[kevinsmb]

With my Biology exam coming in 2 hours, you saved me for my genetics section!

[jessjea89]

Thank youuu for making this video! I thought I was never going to understand this, and now I do... You saved my GPA! =p

[bronproctor]

i think you just saved me from failing my exam tomorrow. thanks!

[MEDddie]

AWESOME! GRACIAS Hermano!

[commonagrotiate]

Thank you!

[solakaboy]

thanks bro, cleared things up for me.

[kerker90]

This helped so much! Thank you :)

[pusho12]

How many marks would a question like this generally be? Seems like a long time to take if it's only a 2 mark question or something similar

[pl4gues]

what's the difference between Autosomal and X-linked

[MrRheem]

@pl4gues X-linked is carried on the sex chromosome X, so XX for female, XY for male. Autosomal is any characteristic NOT carried on the sex chromosomes.

[andersonangels4]

Thanks for the simple, easy-to-understand-and-follow explanation! Greatly appreciate it!!!!

[WhaddupKaysar]

Thanks douche.  You're the best!

[nathou8]

WOOOOW thank you, i will now pass my exam tom. morning!

[ronjonsilver]

HERO

[nakkedpyro]

wow thank you so much. That was an easily understandable well explained video thanks so much.

[cokepep2003]

taking the Mcat tomorrow, thank a lot for the information!!!

[bkath3]

mate you are a life saver! :D

[joser590]

Thank you so much!!! My prof explained it the same way but this video really refreshed the knowledge over the weekend.

[Bloodhawk191]

Thank you so much! I have been enlightend.

[volvagia333]

That was AWESOME!!! TY

[ZIrani1]

thanks a lot... my teacher in the US can't teach this well... Aussie all the way.. g'day mate

[angrycartman]

Thank you Mr.Douche xD

[cmidlo23]

i love you

[mukkubhatia]

too good sir.but i want the pedigree analysis of myotonic dystrophy

[333irani333]

tought it better than my professor. thank you

[sherlockholmes88]

A Masterclass thank you!

[foxman1234]

Thank you!!

[kguknow]

wow thanks a lott now i understand pedigree's soo much more ;)

[didaktus90]

you rock!

[ifrit1780]

wow! This is great! Thanks!

[booboox32]

omg THANK YOU!! that helped alot!

[noobling]

GREAT teaching! keep up the good work man!

[Tholius]

Thanks

[Pearlsethi]

realllllllllllllllly helped....accent is quite nice too lol

[snorcutter]

Man this video is great, really helped me.

[Lovepeace25]

Thanks for this. A clear, friendly and patient explanation. :)

[anushakher]

i've got a test on this tomorow thanx a lot!!

[captainmorgan6666]

this video just saved my ass. i love newzelandfolk

[callanzz]

@captainmorgan6666 I think he's an Aussie but yes great vid, thanks.

[A619A]

i love your accent :)

[Jtran84]

Quick tip: it's recessive if skip generations

[lifeamania]

what do u mean by skip generations?

[lifeamania]

thank yu so much sir for your wonderous guidance . but i have doubt sir. when we start analysing the options to workout ,then why do we assume that the other one will be completely recessive?like if the abnormal one is AA then why the mother should be aa ? i hope you understood my question ......... kindly answer. and iam preparing for my competition exams so is their a short trick to solve such questions quickly? can y post some videos to solve them with short tricks? thank you sir once again

[sasalurve]

Omg, thanks for your tutorial. i have a genetics test later in the afternoon, and you've helped me so much! thanks a lot!

[keishoos]

I wish I found this three hours ago when I started studying for my bio test. Many thanks!!

[evilbutterfly91]

I have my biol exam on Monday and your videos are fantastic! kudos to you! :)

[godzac]

The best podcasts I've ever listened to. I have been listening to all of them over the past few days.

[HolyIndignation]

Good sir, you are wonderful.

[bakwasbankaro]

ah, Douch you have done it again.

made is so easy, Everyone should really watch dis video

[pisshorse69]

helloo pikel

[pikpikel]

hi bio class ^.^