0:47 - "Thus, the action potential passes to the new cell" - makes it sound as though a single EPSP automatically results in an action potential in the postsynaptic cell, which is not true. PSP's are graded, they don't follow the all-or-nothing law like action potentials. Action potentials do not "pass" to the postsynaptic cell. Postsynaptic neurons do their own calculations aggregating info from the MANY neurons which synapse on them, and then decide whether to fire their OWN action potential.
This is depicted as a synapse in the central nervous system and thus acetylcholine is actually not a good example as there presumably is no true synapse for this transmitter in the CNS, GABA or glutamate would fit the movie better
The action potential does NOT simply pass to the next cell as the video suggests. Instead, the action potential in the presynaptic terminal causes the neurotransmitter to be released (as shown), which may cause an EPSP in the postsynaptic dendrite. The EPSP passively moves through the dendrites and soma to the axon hillock and, if it is strong enough to bring the membrane potential there to threshold.
If im not mistaken dosen't an action potential cause voltage gated Ca2+ channels to open allowing Ca2+ into the cell which in turn causes the neurotransmitters to exocytose into the synaptic cleft.
Yeah, your right id say, because dosn't calcium come into the cell and join other calcium particles in the cell and then out of the other channels will come potasium?
Hypothesis: the state of human sentience and cognition, ie. that "thing" in the back of your eyes that wakes up and realizes a yawn after slumber, is a bio-electrical phenomena. Your state of consciousness is a bio-electrical phenomena.
What system has been built from all the activities inside the collection of neurons to bring the state of cognition to be?
Whoever writes the paper of Papers detailing the mechanisms and systems of cognition are in the history books, forever. Go for it, fella's
Inhibitory neurotransmitters don't close a post synaptic channel. They actually just increase the membrane's permeability to Cl- ions which serve as a voltage clamp preventing any further action potentials from being generated. So to say they close is incorrect. They open channels, just those specific to ions besides Na+ or Ca2+.
@TiborZutron There is one thing I don't get. Shouldn't it be the other way around?? Na+ that enters the post-synaptic cell depolarizes the K+ ions, HOW? they are both positively charged, and hence, by chemical terms, should repel each-other... So shouldn't Na+ be the hyperpolarizer that causes the K+ ions to leave the axon? and since Cl- is negatively charged, shouldn't it attract the K+ ions into the cell? How do they do the opposite?? I swear taking Chem and Bio together confuses me more :S
@Xshado2 Think more about diffusion and less about the charges. The charges are certainly important but so are the concentrations of ions and the permeability of the channels to each of the ions. Google the Goldman-Hodgkin-Katz equation. A good explanation of this equation may help.
Think more about diffusion and less about the charges. The charges are certainly important but so are the concentrations of ions and the permeability of the channels to each of the ions. Google the Goldman-Hodgkin-Katz equation. A good explanation of this equation may help.
be aware this video does not mention the step where the Ca+ glates open, and sodium rushes in, which is what causes the neurotransmitters vessels to dock.
Ok. This video fails to show the role of Calcium voltage-gated channels.
The action potential does not trigger the opening of vesicles; it opens the Ca voltage-gated channels, allowing Ca to enter the presynaptic cell. From the Ca, a protein on the Ca tells the vesicles w/ the neurotransmitters to exocytose!
HELL YEAH CLATHRIN COATED PITS! What a crude description this video includes. The sponatneous assembly and disassembly of clathrin coated vesicles in cells deserves a more detailed representation.
love the work here
clairebehun 1 month ago
0:47 - "Thus, the action potential passes to the new cell" - makes it sound as though a single EPSP automatically results in an action potential in the postsynaptic cell, which is not true. PSP's are graded, they don't follow the all-or-nothing law like action potentials. Action potentials do not "pass" to the postsynaptic cell. Postsynaptic neurons do their own calculations aggregating info from the MANY neurons which synapse on them, and then decide whether to fire their OWN action potential.
therebelwaltz 5 months ago
Comment removed
therebelwaltz 5 months ago
awsome
kinkymango1 7 months ago
Have you go a copy of the script text?
QueenBee3xxx 8 months ago
@QueenBee3xxx
thetreeceman 7 months ago
gonna need this for tomorrow!
torosyan 8 months ago
@Priprislow Moi aussi! C'est genial
TheCultureCombo 9 months ago
This has been flagged as spam show
Hi, could someone tell me why you should take a Dopamine reup inhibitor rather than an SSRI or vise versa?
What difference will you find if you take one rather than the other?
Thanks!
BIGPIMPINUPDANYC 11 months ago
Where is the Ca+
dimitrigunit 11 months ago
He dumps he smiles..........
anandanaga999 1 year ago 2
@anandanaga999 roflmao!!
iwork4them 9 months ago
This is very helpful, but I think the Ca IOns are missing
Monaistmeinliebling 1 year ago
Thank u!
A short, but yet a clear video.Much better than many other videos about this topic.
Bayar2008 1 year ago
thanks
NeverDependOnMe 1 year ago
Thanks for this great video;getting a visual is really helpful in understanding.
antinkansas012 1 year ago
yeah i finally got it..
mjhtisdbst 1 year ago
This is depicted as a synapse in the central nervous system and thus acetylcholine is actually not a good example as there presumably is no true synapse for this transmitter in the CNS, GABA or glutamate would fit the movie better
Nilbys1 1 year ago
realy i like it
manar50001847 1 year ago
you didnt mention about the ca comeing in
MrCatalano14 1 year ago 2
damn..the way our brains work is far beyond merely complex.
JuiceofVM 1 year ago
what does thus mean??? lol
EyeWearMySunglasses 2 years ago
love the vids keep them coming
me28andholding 2 years ago
i love youtube. and i hate ap biology =D
MicFrosty88 2 years ago
haha
hinterher 2 years ago
Thanks! this really helped me on my biologytest!
ThunderPhil95 2 years ago 28
The action potential does NOT simply pass to the next cell as the video suggests. Instead, the action potential in the presynaptic terminal causes the neurotransmitter to be released (as shown), which may cause an EPSP in the postsynaptic dendrite. The EPSP passively moves through the dendrites and soma to the axon hillock and, if it is strong enough to bring the membrane potential there to threshold.
mschmolesky 2 years ago 2
whats an EPSP?
indywordfx 2 years ago
If im not mistaken dosen't an action potential cause voltage gated Ca2+ channels to open allowing Ca2+ into the cell which in turn causes the neurotransmitters to exocytose into the synaptic cleft.
LeeDiddy990 2 years ago 2
Yeah, your right id say, because dosn't calcium come into the cell and join other calcium particles in the cell and then out of the other channels will come potasium?
indywordfx 2 years ago
lauren = neural.. jsut swap the letters around!
TheVesterLauren 2 years ago
oh sure, makes perfect sense to me -- i just need to watch this about 68 more times.
iViewYouTube 2 years ago
hehe, he said vesicles
ratzskinakie 2 years ago
Thta's all? F*ck! Now I can understand all this crazy things xDD! That waas so easy to understaand thanks ;O;!
steffany578 2 years ago
i keep saying " holy synapse!" but i dont know why...
olive0drab0fad 2 years ago
ahhhhh! i get it now!! thanks!
bassbiatch9 2 years ago
Comment removed
LEYTONLOVER333 2 years ago
why cant americains pronounce synapse properly, its SYNAPSE not SINAPSE
ReaperStrainPrds 2 years ago
they pronounced it right, english or american. it is pronounced 'sin' - 'apse'
it comes from the latin word for meeting or coming together, think 'synthesis, synonym, symmetry, syntax, syllable.
i thoguht it was sy napse too, i disputed it with my biology teacher but he convinced me its sin-apse. (and he is english)
mduckworth 2 years ago
Then why would my university lecturer say synapse, im sorry but im gonna trust a university lecturer over a biology teacher
ReaperStrainPrds 2 years ago
apology accepted
mduckworth 2 years ago
potaeto potahto... lol
lyzahluvzsisko 2 years ago
Man.....neurons are cool!
400th 2 years ago
oh dear god
ladyzee91 2 years ago
Hypothesis: the state of human sentience and cognition, ie. that "thing" in the back of your eyes that wakes up and realizes a yawn after slumber, is a bio-electrical phenomena. Your state of consciousness is a bio-electrical phenomena.
What system has been built from all the activities inside the collection of neurons to bring the state of cognition to be?
Whoever writes the paper of Papers detailing the mechanisms and systems of cognition are in the history books, forever. Go for it, fella's
mergatroidal 2 years ago
Inhibitory neurotransmitters don't close a post synaptic channel. They actually just increase the membrane's permeability to Cl- ions which serve as a voltage clamp preventing any further action potentials from being generated. So to say they close is incorrect. They open channels, just those specific to ions besides Na+ or Ca2+.
TiborZutron 3 years ago 9
@TiborZutron There is one thing I don't get. Shouldn't it be the other way around?? Na+ that enters the post-synaptic cell depolarizes the K+ ions, HOW? they are both positively charged, and hence, by chemical terms, should repel each-other... So shouldn't Na+ be the hyperpolarizer that causes the K+ ions to leave the axon? and since Cl- is negatively charged, shouldn't it attract the K+ ions into the cell? How do they do the opposite?? I swear taking Chem and Bio together confuses me more :S
Xshado2 9 months ago
@Xshado2 lol ur right!
iwork4them 9 months ago
@Xshado2 Think more about diffusion and less about the charges. The charges are certainly important but so are the concentrations of ions and the permeability of the channels to each of the ions. Google the Goldman-Hodgkin-Katz equation. A good explanation of this equation may help.
quickblondfox 4 months ago
This has been flagged as spam show
@Xshado2
Think more about diffusion and less about the charges. The charges are certainly important but so are the concentrations of ions and the permeability of the channels to each of the ions. Google the Goldman-Hodgkin-Katz equation. A good explanation of this equation may help.
quickblondfox 4 months ago
be aware this video does not mention the step where the Ca+ glates open, and sodium rushes in, which is what causes the neurotransmitters vessels to dock.
b20hatch 3 years ago 3
What about the Voltage-gated calcium channels?!
JackieGeeNinja 3 years ago
Ok. This video fails to show the role of Calcium voltage-gated channels.
The action potential does not trigger the opening of vesicles; it opens the Ca voltage-gated channels, allowing Ca to enter the presynaptic cell. From the Ca, a protein on the Ca tells the vesicles w/ the neurotransmitters to exocytose!
It's not the impulse! It's the calcium!
JackieGeeNinja 3 years ago 3
Your sure about this right, because its going on my bio final?
thanks
LEYTONLOVER333 2 years ago
HELL YEAH CLATHRIN COATED PITS! What a crude description this video includes. The sponatneous assembly and disassembly of clathrin coated vesicles in cells deserves a more detailed representation.
loneyrw 3 years ago
oh man, im hatin this topic :D
neonschwarz 3 years ago
Oh man, that thought was invoked, by a neuronal synapsis. :D and was typed by your motor cortex where more synapsis exists.
Hate more this topic :D
sirfreakman 3 years ago
tomorrow i will be writing my 3h exam on this shit... -.-
mickfragger 3 years ago
thanks for this! i learned more in one minute than i did in two days of textbook explanation.
eugdog106 3 years ago 3
haha they tried to teach this to us in five minutes , needless to say i didn't get it at all
LEYTONLOVER333 2 years ago
I GOT THE MCAT BLUES :(
littledotte 3 years ago 3