Added: 1 year ago
From: DoctorNajeeb
Views: 21,586
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  • Wish this dude would teach me...

  • " Oh, someone found a mistake in my spelling, I'm always weak in spelling so i prefer to write it like this (writes a smudges C3 convertase)"......... Ahhh a True Doctor XD!!!!!!!!!!!

  • " Oh, someone found a mistake in my spelling, I'm always weak in spelling so i prefer to write it like this (writes a smudges C3 convertase)"......... Ahhh a True Doctor XD!!!!!!!!!!!

  • C3 convertase is C4bC2b in Europe, C4bC2a in North America.

    He is just using European nomenclature

  • U HELP ME SOOOO MUCH

    THNXXXXXXXXXXXXXXXXXXX

    

  • so watz correct about c3 convertase

    

  • haha i remember learning this at medical school. the doc used C4b2b but our texts listed C4b2a. or the other way around. 

  • C3 convertase is C4bC2b in Europe, C4bC2a in North America.

    He is just using European nomenclature

  • C4bC2b in Europe, C4bC2a in North America

  • This is what wikipedia has to say about C3 convertase,

    " C3 convertase was, in classical terms, C4b2a; however, in keeping with the number and letter scheme, it was changed to C4b2b in the 1990s to reflect the enzymatic activity of the C2b fragment" I don't think articles in wikipedia are validated by peers ? dr4humanity can you critic my comment ?

  • I have never seen anyone explain the complement system as Dr Najeeb, hes amazing.

    c4b2a is c3 convertase is used in the new books and c4b2b convertase which is used in the old books. I have asked my lectures , she said they both right to use but its better to use c4b2a. so even if u right it in the exam u shouldnt loose any mark :p

  • According to Cellular and Molecular Immunology 6th edition by Abul K. Abbas, Dr. Najeeb is correct by terming C4b2b as C3 convertase.

  • @pikpikpikkemand but my book also says c4b2a is c3 convertase. I'm sorry but when was this book published?

  • @RumanaT i ve got "veterinary immunology" 8th edition and it says C4bC2b is C3 convertase. it is published at 2009. its weird though because it should say C4bC2a..... i guess is one of the few details that scientists argue about.

    But im sure that the correct one is C4bC2a.

    My opinion, we better ask the teacher and write what they prefer. much safer

  • @dr4humanity C4b2a is C3 convertase

  • Hairy Mother :) Excellent basic way of explaining that will stick in my brain.... You should teach at my medical school.

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