Rosetta@home

[kyheadup]

I'm very proud of donating my free CPU time to help this project.

[wellwellwellall]

oh intuition and the rosetta. Sacred geometry......:) good luck

[CreatormasterF1]

Why only 240p?

[mclaren777]

Great video and a great piece of software. I graduated from UW with a degree in biochemistry and I wanted to thank your team for doing such excellent research.

[IloveYOUviruses]

at least this isn't as stupid as SETI

[rm3cpp]

I loved the mention of the educational possibilities of the project towards the end of the video. Although it's certainly an even more blurry goal than that of accurately predicting protein structures, it is an equally beautiful one. It is wonderful to see researchers thinking about things like that - because that is what we ultimately need, a world of creative people striving to understand the universe.

[bestSVMS]

why are they trying to compute the shape of its already known?

and how is this different from f@h?

[CarlKenner]

@bestSVMS, it's to test whether they are computing it correctly. It's quite hard to compute, and they keep improving their algorithm. Not all of the tasks it computes are tests against known shapes, some are actually predicting completely unknown shapes.

[christinio]

this still doesn't explain how it helps that you know the lowest energy levels. somehow from the prediction of how molecules can connect you'll be able to cure cancer? HOW?! this video sucks as it tells absolutely nothing to the user. after watching my guess is that even seti has better chances of success than this. sorry, you need a PR manager

[MiniZiper]

It doesn't help you being a dumbass either.

Rosetta's goal isn't to know the lowest energy levels, it's to accurately PREDICT the molecular shape of a protein w/o the laboratory hassle.

And if you passed High School biology, you would know that much of the protein's function depends solely on it's structure.

[BigBananaMan]

Well how does understanding quantum mechanics solve our energy problems?

[crowhawk]

Nice idea but how much of this research actually benefits ordinary people? As opposed to the pharmaceutical multinationals who manufacture expensive medicines beyond the price of most people?

[MiniZiper]

Well, you could use R@H knowledge and invent your OWN medicine, and give it away for free. But that would not work for you, now would it?

Whether laboratories around the world charge too much or not, well we could ask the same whether the car industry charges too much or not for their cars.

R@H cares about the KNOWLEDGE. And as far as I know, the knowledge is free to use.

[BigBananaMan]

How on earth do you get it to display as they showed at 4:35? It's not a function of the boinc manager.

[MiniZiper]

That's the screen saver. If you go to boinc manager, then to tasks, and select the running tasks, and option to the left will appear that says: "show graphics". Voila.

[kpstx]

I like this. It is a nicely done promo. I got directed here from Autoimmunity. I actually work in Transplant Immunology at UT Southwestern.

[Ujikaweapon1]

Amazing! I love this technology. Exceptional video.

[RationalEmotive]

In the near future where computing power will even be more important than today, the competition for users' unused cycles will become more intense. It is thinkable that marketing will become essential to secure users willingness to contribute cycles. Attractive spokespersons will be hired to promote the projects and so on.

[Vambreaker23]

Why does its been called Rosetta@home?

[Heghogies]

Because you can use Rosetta @ home. (at home)

[rabarbatif]

What's music?

[54spiritedwill54]

Good work. Made it all clear for me.

[blobrana]

Cool - i used to run seti stuff

[plusmavideo]

lol i started with seti too some ages ago

and now run 6 projects on 5 pcs lol

[ciucinciu]

did you find anything?

[plusmavideo]

yeah, my virginity which was accidentaly lost when i felt from a tree

lool

[polkapete]

awesome concept. i hope it works :)

[buddahmastahz]

I understand the function of Rosetta and using remote computers for computing, however protein folding is beyond me. I'm a Psych major, and even I'm lost! LOL

[DavidODuvall]

Excellent video! For those of us who have to turn on our furnace/heaters to stay warm, we should leave our computer(s) running 24-7. The computer(s) can help warm your house while contributing to this important research. The result is a no cost contribution to humanity.

[suurishoujo]

If only I could say the same. I'm stuck in Texas where it's only cold for about one week in January. Last February I even made a habit of sunning myself outside the dorms in 80 degree weather...

[fledermaus81]

If anyone has doubts about whether crunching for Rosetta is meaningful, they should look no further than David Baker's Rosetta@home journal (at the Rosetta@home website) - it has some pretty amazing stuff about what the crunched results have meant for their research thus far. Go check it out.

[kronos301]

So WHAT so "amazing" there???????

Protein Data Bank is full of structures

of proteins with unknown function.

WHO needs his "PREDICTED" structures???

About his "enzymes" I am very skeptical.

Nature and SCience are not relible journals

nowdays.

[Lahmy88]

i run Folding@Home on my computer, the most powerful distributed-computing project operating today, partly because of the recent inclusion of Playstation 3s. I'd like to see if its possible for many of these Protein-researching projects to maybe join together or share research? I know its probably a matter of each University wants to keep funding to itself, but if its in the interest of solving many awful Human diseases.. why not?

[AJenbo]

They do not use the same metode and dosn't look for excatly the same thing, look it up on wiki for more details.

[EvaSDK]

As far as I know, folding@home doesn't provide a BOINC client, I have no interest in contributing to this project if it doesn't make it easy for me to add it to the tasks my computer does while I'm away (and last time I tried, the client didn't really behaved well with other jobs on my boxes).

[HazeyLazy]

my name is rosetta....

[Aqua1986]

Excellent video! I'm a rosetta@home user already!

[fledermaus81]

I agree with the scope of importance of this project with the two previous writers. We need more crunchers for Rosetta!

[fibertech9]

Tell others about this video and that way we can all donate more time to finding cures to diseases!

[drVitall]

Rosetta@Home is a best and most worthwhile distributed project out there.

If we (as humankind) will develop a fast way that let us reliably predict shape of protein from sequence, it will let us design medicines/cures in a new more powerful way. Almost every peace of our body or blood or immune system - is a pure mix of proteins. Being able to design billions of artificial one we make sky is our limit. Real cures that have no side effects. Ability to grow arm instead of lost one. Cure for aging.

[xenoalien]

watch this related video: youtube "DOT" com/watch?v=gE3N8v1RzJo

[iddqd123]

thats so a great idea :)

[Golem386]

Great video!

[Baini1]

yeah rosetta 4tw

its great that maby your PC is able to heal you in reallife ^^

[Kennyemo]

join Team "ESL" !!!

ESL 4tw :D

[Anchorage1988]

very nice project!

I've started with it now and i'll show it to all my class in biology lessons, because this is our actual theme

[zimxiii]

Outstanding promotion! I'm a long time supporter of Rosetta as well, cheers to everyone!

[LordMoku]

Very very interesting movie!

I am a proud supporter of Rosetta@home and I will continue to give my imput for years to come! Here's to a better future! =D

[juicysuit]

Really like the soundtrack. The acoustic parts are very pretty and the computery parts very wierd. Good stuff!

[xenoalien]

I am glad to see a video that goes in to detail about Rosetta@home. Distributive computing truly is a great way the public can help medical science.

[BlissfulKnowledge]

A very exciting project, and can't wait to see the results of this.

[usrhlp]

Well he is probably the worst speakr i have ever seen but i have to admit that made me want to sign up!! Here goes! :D

[ALHZWOLLYWOOD]

Nice! Good work. Made it all clear for me.

[ilovesatan666]

Keep it up! More publicity! More users! More results!

[bobbir866]

Awesome! nice work. I've been running Rosetta@home since it started.

[spotlf87]

Very good video