The Sodium Potassium Pump is an active transport mechanism. 3 Na+ ions bind to the protein channel and ATP provides the energy to change the shape of the channel that in turn drives the ions through the channel. One phosphate group from the ATP (now ADP) remains bound to the channel. The Sodium ions are released on the other side of the membrane (the OCF) and the new shape has high affinity for K+ ions and 2 of these ions now bind to the channel.
This binding again causes change in the shape of the protein channel and this conformational change releases the phosphate group on the cytoplasmic (ICF) side. In its original shape the channel has a high affinity for sodium ions and when these ions bind again they initiate another cycle!
@jenny07la The Important characteristic about this pump is that both sodium and potassium ions are moving from areas of low concentration to areas of high concentration. They are moving away from their concentration gradient. This type of movement can only be achieved by the expenditure of ATP energy.
@jenny07la The Important characteristic about this pump is that both sodium and potassium ions are moving from areas of low concentration to areas of high concentration. They are moving away from their concentration gradient. This type of movement can only be achieved by the expenditure of ATP energy.
@AndrewIrizarry Nope, its the Na ions first then ATP triggers a conformational change to send it to the extracellular side. If ATP bound first the pump would go straight to the E2 conformation
I am very happy to see the vidoe after you give this Sodium Potassium Pump
Mjhond 1 month ago
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Ondelendo 1 month ago
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anakmudajaman 1 month ago
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bebeheuy 1 month ago
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willamricard 1 month ago
Your Video Is Very Useful Sharing I did not make this video. I found it online on a website called McGraw Hill
bundawartini 1 month ago
Man...this is some serious engineering bullshit.
Draxis32 3 months ago
que¿
sasfa124 4 months ago
its wrong!
x3BlackKeys 4 months ago
Binding of cytoplasmic Na+ to the pump protein stimulates phosphorylation by ATP
Phosphorylation causes the shape of the protein to change
The change in the shape realeases the Na+ and extracellular K+ binds
The Bondage of K+ releases the Phosphate group
the realease of the phosphate group changes the shape of the protein back to its original form
K+ is released and the Na+ sites are ready to bind Na+. The cycle continues^^
I have a quiz on this today :)) wish me luck!!
TheTiggy26 4 months ago
thankyou! this really helped me with my project!:)
mollyLynn9715 5 months ago
The Sodium Potassium Pump is an active transport mechanism. 3 Na+ ions bind to the protein channel and ATP provides the energy to change the shape of the channel that in turn drives the ions through the channel. One phosphate group from the ATP (now ADP) remains bound to the channel. The Sodium ions are released on the other side of the membrane (the OCF) and the new shape has high affinity for K+ ions and 2 of these ions now bind to the channel.
jenny07la 6 months ago 5
This binding again causes change in the shape of the protein channel and this conformational change releases the phosphate group on the cytoplasmic (ICF) side. In its original shape the channel has a high affinity for sodium ions and when these ions bind again they initiate another cycle!
jenny07la 6 months ago
@jenny07la The Important characteristic about this pump is that both sodium and potassium ions are moving from areas of low concentration to areas of high concentration. They are moving away from their concentration gradient. This type of movement can only be achieved by the expenditure of ATP energy.
jenny07la 6 months ago 8
This has been flagged as spam show
@jenny07la The Important characteristic about this pump is that both sodium and potassium ions are moving from areas of low concentration to areas of high concentration. They are moving away from their concentration gradient. This type of movement can only be achieved by the expenditure of ATP energy.
jenny07la 6 months ago
@jenny07la I can't thank you enough! My notes were incredibly vague in regards to this section.
OoUNL3ASHEDoO 2 months ago
ok
MegaFearGod 6 months ago
What phase is represented by the large scale movement of sodium ions during the change in membrane potential
westsidemuderfukerr 6 months ago
nice
KatiushaVN4 9 months ago
no sound :(
stealingdistances 10 months ago
I thought ATP binded first then 3 Na+?
AndrewIrizarry 10 months ago
@AndrewIrizarry Nope, its the Na ions first then ATP triggers a conformational change to send it to the extracellular side. If ATP bound first the pump would go straight to the E2 conformation
SuperDuperSentinel 4 months ago
NICE
dabigplaya2389 1 year ago