Animal Testing - Good Science? Or Pointless Cruelty? Part 2

[Frostylete]

Use it on prisoners who are on death row!!!

[anni97rocks]

this is a very old video. it is history. ther has been HUGE developments THANK GOD. i dont know where they find people to do those jobs

[Jesiibabii1]

I AM TOTALLY AGAINST IT, I DONT THINK ANY LIVING THING IN THIS WORLD DESERVES THIS! AND WHO EVER SUPPORTS ANIMAL TESTING NEEDS TO GET THERE HEAD DRILLED AND TREATED LIKE SHYT!

[xxEmoGirl11xx]

so when a person is getting beaten up or bullied or some shit like that, theres gotta be a lot police and courts involved, but when an animal is being used this way, then everyone turns their f***ing head and pretend like nothing is going on ?!?!?!?!?!? WTF IS WRONG WITH HUMANITY !!! we are suppose to be smart !!!! not be dumbshits !!!

[naureensd]

piece of crap below me

[craftbrosify]

I support animal testing

[Treefrogcalidryas]

@craftbrosify Then you are a dickhead

[craftbrosify]

@Treefrogcalidryas well enjoy having no vaccines, shampoo, many medicines, or have of the other stuff you use to keep you healthy. Frankly everyone here supports animal testing considering you have EATEN animals and you have also used products that were all tested on animals.

[littlestoked]

@craftbrosify Did you watch the video? There are so many other alternatives to testing products inhumanely on them. I agree that everyone has used products tested on animals, but that doesn't mean they support it. I can honestly say I try to buy everything free-range, grass fed, and my products not tested on animals. But guess what? It's not that easy seeing that nearly everything sold in your local market is tested on animals

[alexsanimalland]

stop animal testing its cruel and evil what if someone put u in a cage gave u shoots and poisen made u sick or driled a hole in your head what is wrong with these stupid scientists they seriously dont know what pain they are causing these animals

[worldwildwest]

Just watched a video Titled: "Wasted Lives: How are animals used? " at 2:51 you'll see a demented British Prick Hitting a Frightened Dog, i guarantee You won't forget this Shit faced Doctor after you See him hitting a poor Animal.

[laichi16]

Paxil, the antidepressant drug, was given to pregnant women because they did not cause birth defects in animals, but guess what happened to the human babies born. That's right; they were born with birth defects.

[laichi16]

7 people don't like the ugly truth.

[HelmGarrot]

0:20, did that "man" just suggest human testing. What a prick.

[Asianspice0]

@HelmGarrot Agreed what a prick, human testing to cure human diseases, absolutely ridiculous.

[xXFlockofGriffinsXx]

Ommigosh! It was narrated by Alan Davies! I knew that voice sounded familiar! :D

[keruixin]

I'm not sure what to believe...I feel like this video is presenting an argument that clearly has more than one side but is overlooking the others completely in order to make its argument seem stronger. I think the people at PETA WOULD do testing on people if they could even if they say they disagree; I really do. All I know is i would kill every rat in the world to save a child terminally ill with some illness. At some point, a line must be drawn.

[ThePigThatGoesBree]

@keruixin Good argument. But as shown in this mini-documentary video, it shows it's quite pointless to test on animals. Because of the obvious facts their genes and DNA and biological setup is quite different from us and nothing good comes from the animal research.

[keruixin]

@ThePigThatGoesBree I did more research, and I think you're ignoring the fact that pretty much every successful drug on the market was tested on animals as well--not just those failed ones. Also, whenever people get valve replacements, the most common donor is a pig. The only other solution is to use human valves. How is that useless? In addition, pig skin is almost identical to human skin, which makes it ideal for the testing of sunscreens and lotions.

[ThePigThatGoesBree]

@keruixin Name 5 extremely successful drugs that were tested on animals and have had an impact on human life for the positive because it was necessary? I said necessary, because lotions and sunscreens aren't really important. They're just good things to have.

[keruixin]

@ThePigThatGoesBree Heart valves-pigs; insulin-many animals with similar insulin to humans; vaccine for leprosy-armadillos; polio-non-human primates; cloning-sheep-definitely necessary for future research; HIV medication that keeps the virus in the lysogenic cycle; sunscreen-pigs, which is necessary because it prevents skin cancer; and many more. I agree that animals must be treated more humanely, and killing them should be a last resort. The treatment of the dog, in particular, sickens me.

[eburshtan0720]

A scientist studies the planets or ecosystems among other fields. To drip pestiside into a rabbits eye is not science. Watching this is extremely disturbing.

[xxiRapeZombiezxx]

5 people dont have souls whatsoever.....thoes heartless bastards!!!!!!!

[sixpounder6169]

i would muder a bastard commiting these atrocities!

[noratmedicine]

2005

Given that many of these investigational anticancer drugs eventually fail, the animal models on which clinical trials are predicated must at best be limited in power, and at worst wildly inaccurate. Dr Alexander Kamb, Global Head of the Oncology Disease Area at the Novartis Institutes for Biomedical Research, Nature Reviews Drug Discovery, 4, 161 - 165.

[Casshyr]

The usefulness of animal models have been increasing, as we increase our understanding of how genes work and how they are regulated. Back in 1960s, people don't really understand genetics, and hence many animal models fail to be useful when applying to human medicine. Now that is beginning to change: for example, see paper "Transgenic Animal Models of Huntington's Disease." PMID: 21225414

[cathavenfostermom1]

@Casshyr, so your saying that even though bioengineering is based on a fourty your old model,

which suggests that genes work completely independantly, and that you can safely transfer them

from one species to another without them interacting, which has been proven false on many occasions,

that engineering test animals is perfectly safe and affective, and there is no chance that you might be doing

something wrong. I've worked in a lab, so I know what I am talking about.

[Casshyr]

@cathavenfostermom1 No, that's not what i'm saying. i'm merely pointing out the fact that yes it's true in the olden times animal models are not that meaningful, but this has been changing with better technology + better understanding. Obviously, we still have a long way to go, but this highlights all the more crucial for more basic research. And yes, I also have worked in a lab, in fact, I am still right now (i'm a grad student studying bioinformatics)

[cathavenfostermom1]

@Casshyr, they say that knockout mice are a great advance animal science.They shut off one gene in the mice to see what it does, saying that since mice are so close genetically to humans, it can show us something about human genetics.

The problem with that is simply that the genes we share with mice act differently in us than in mice.

A gene that produces a particular protein in the knockout mouse,

might make a completely different protein in humans.

You can't study human genetics that way.

[Casshyr]

@cathavenfostermom1 You are quoting the minority. In 2002, the mouse consortium deduced that up to 80% of the genes share orthologs in humans, suggesting the 80% of the genes share similar functions. Even if the ultimate phenotype is not the same, we can at least learn a lot about biological pathways that take place. A few well known examples are: Hox genes in setting up anterior-posterior development, Notch gene in angiogenesis pathway, and PcG in epigenetics.

[cathavenfostermom1]

@Casshyr, thanks to research done on dogs, heart by pass surgery was put off for years.

It was shown to not work in dogs.

[Casshyr]

@cathavenfostermom1 research in pigs lead to the idea that we can replace defective heart valves with pig valves, now a practice commonly practiced in clinics

[cathavenfostermom1]

@Casshyr, the idea that you can replace a part of an organism's body with the equivelant body part from another organism's body is as old as the kidney transplant.Its the same basic concept. Since transplants had been in use for years, and we have cadavers and we also have computer models, it could have been studied without the use of animals.

[Casshyr]

@cathavenfostermom1 Even common procedures like kidney or liver transplant still have quite a big mortality rate in them, that's why there are still a lot of basic research studying biological processes like liver regeneration to further improve the therapeutic techniques, and such studies is impossible to test in humans without further stressing the patients. And computer models cannot replace animal models, I know that cuz that's my specialization! Other bioinformaticians will agree

[cathavenfostermom1]

@Casshyr, sorry it took me so long to get back to you, I had to right a paper on bioengineering.

Want to continue this discussion? There are now more ways of studying liver regeneration, in vitro studies which use tissue taken from human liver, computer modelling is now very sophisticated, with virtual human organs and virtual metabolism programmes.

[Casshyr]

@cathavenfostermom1 The ways you mention cannot replace animal model because they have their own caveats. Namely:

1) computational model is not sophisticated enough to model real biology (again, I know this cuz I specialize in it). Yes, the math all look very sophisticated, but trust me, the prediction is not good enough to replace animal model. Maybe in like 100 years, this will change, but for now, no.

2) using human tissue => can't, see my next post for more...

[Casshyr]

@cathavenfostermom1 Problems with tissue culture: it's just doesn't represent the whole organ. Organ is made up of multiple tissue types, in a certain spatial organization. You just can't represent an organ on a layer of tissue. Also, if you want to link organ development to another organ, like say coordination between the brain and liver, there's no way you can capture that on tissue culture.

[Casshyr]

@cathavenfostermom1 Sorry about the spam, but i'm not saying animal model is perfect. This is why we need all the tools we can get: i.e. computer modeling, tissue culture, animal modeling... all these don't replace each other, they COMPLEMENT each other. Also, lets not forget that even in computer modeling, a lot of programs depend on animal models to infer to humans, for example, comparative programs that use evolutionary probabilistic model for gene function prediction is such.

[cathavenfostermom1]

@Casshyr,When a foreign gene makes it into the DNA, there is no telling where along the strand it will end up.

The inserted gene could disrupt any number of naturally expressed traits depending on where it lands.

One common position effect is tha teither the foreign gene or the native genes in their vicinity get shut off;

they are no longer able tp produce their protein.

These variable and others, make using genetically engineered animals even more inaccurate than using

natural ones.

[Nightshadeco]

Thank you Thank you Thank you for this video, I have been searching for people who have the right point of view about animals, especially testing.

I am SO happy to know there are people in the world who care enough to do something about it!

[noratmedicine]

“Animal studies are done for legal reasons and not for scientific reasons. The predictive value of such studies for man is meaningless.”; - Dr James D. Gallagher; Director of Medical Research; Lederle Laboratories; Journal of the American Medical Association; March 14 1964.;

curedisease. net

[theshadowmannikolaus]

i pay me life to stop animal cruelty and pointles experiments

[imarobotnow]

i always though animal testing was okay for finding cures in disses. How wrong was I !!!!!!!!! Thank you for showing me this

[brandonent50]

before posting an opinion you should always look at the other side of a topic you might get different results

[Dumpweed131]

@brandonent50 ooh really.. I had no idea cruelty had two sides? Maybe the other one, that u would present to us is reasonable and justified? To me.. humans are the most disgusting and revolting beings on the Earth!

[Americano951]

@brandonent50 true but there really is no good side to this. its cruel. no matter how you look at it

[SHAWNGALEADROCK]

@brandonent50 yes and you know what test on animals aren't accurate as much as testing on a human being lets try it you shall we? :) and bdw don't worry you will not show any pain during these test we'll take of your voice.. in the end of the end you will be the saviour of humane kind.... there are alternative that are cheaper and quicker there is need of such a thing to be performed on animals or a humane being. one of them it's called "3T3 Neutral Red Uptake Phototoxicity Test"

[MsDementedArts]

I am so glad to see that the man Geroff Thomas with RP, the same disease I have, is against animal testing. I thought I was the only one. I wish that people would just think about what they are doing before they do it. Especially when it means the life or death of another creature.

[MsDementedArts]

"They've built fortunes on animal experiments. . .Why would they want to change" The saddest truth I've ever heard. . .

[noratmedicine]

The provision of legal protection to drug co's is the main reason for animal exp. Their products simply would not pass a valid test. It has no scientific value, just the opposite. “Animal studies are done for legal reasons and not for scientific reasons. The predictive value of such studies for man is meaningless.”; - Dr James D. Gallagher; Director of Medical Research; Lederle Laboratories; Journal of the American Medical Association; March 14 1964.; curedisease. net mrmcmed. org navs. org

[Nightcrawlerinsweden]

instead of using animals in vain we should do experimenting on murdered and extreme criminals instead of killing a person in the electric chair why not do experiments to him untill he dies? he probably deserves it anyway. this is so bloody wrong, i was to a demonstration against experiments on monkeys in stockholm just a few weeks ago

[Kristin3030]

Animals are equal to humans in science as lifeforms on Earth!

[REMMO11]

Gill you mother is ready to start fucking agin. Crazyy Fucking

[peinsama666]

Humans deserve to rot in hell forever.

[SERiFExo]

@peinsama666 agreed.

[Chikaze01]

Gawd I see photos of animal experimentation and som of them I have no freakin idea what they are tested on. I hate ppl who do things like that to animals. It's not right in this world.

[redryan67]

testing on animals should stop it will never work we have difforent genes they will have a differnt affect to us so why do we still do it? maby they are just ass holes!

[noratmedicine]

@redryan67 Yes. they do it because it does not work, the objective is to hide the fact that a substance is harmful to humans and the environment, that provides legal protection which is very valuable to drug/chem/tobacco etc industries. they have gone to great lengths to dupe the public and have done so very well, even paying peter singer, google 'ajudem nos singer rockefeller ruesch vivisection' curedisease. net is a good site also mrmcmed. org drugtestingconference. com

[mrfolopi]

sigh..... completely useless on animals is what i say...... There were some scientists who were brave enough to inject themselves with the disease and create a cure out of that. That is what i call a hero. And guess what? no animals were hurt in the making of that medicine and the doctor survived

[6maca6]

this vid helped alot on my essay, thanks

[clubamerica16]

me too i also i have to do a an essay on this

[puppyshade]

@6maca6 same XD i'm doing it for HE

[PROFLOP1]

Animal testing is a unfortunate necessity of life. ALL of our modern drugs have needed to be tested FIRST on animals. This is called stage 1 of testing any drug. This is mandatory by FDA.

[1221solstice2012]

To understate the point extremely, people don't deserve to live among animals.

The only problem I have with this video is the word "alternative," as if animal research is beneficial and can't be ended without "alternatives," like saying we need an alternative for wife beating before it can be stopped. Otherwise, 5/5 stars. Thank you.

[PROFLOP1]

This is an open forum

[CrystalleLaker]

absolute pointless cruelty - anyone who can say this is not cruel deserves to be shot - hand me the bloody gun now...

[pashqual]

@CrystalleLaker You are one ignorant person. It hurts my head seeing stupidity like this. My god.

[HOLYSHYTWTFOMGLULZ]

@CrystalleLaker ignorance and irony at its best. read & look at what you're saying, and tell me that's not cruel.