Digoxin: What Should You Know About It?

[dellinspiron17200]

Thanks a lot . It was really helpful.

[stevalianarbone]

Mum had heart failure she was suffering from a murmur. She had irregular heart beat. She was given a dose digoxin in morning (Staff Nurse asked me to give it to her in hospital) and another does (maximum 2) two hours later (Staff Nurse again asked me to give it to her in hospital, doctor ordered it, she said, they had just come on their rounds) and about two hours later she was dead. Yet in the morning she was bright and cheerful. She died of congestion leading to cardiac arrest, 4 month ago.

[jinwig]

I think he made a slight mistake here, Dig toxicity is seen in hypokalemia, i always remember they are opposite. subtherapeutic in hyperkalemia and supratherapeutic in hyopkalemia. It make sense since if you think of the mechainism, if Dig is competing with K then with less K, you will have more Dig.

[jinwig]

Other than that slight correction, very thorough and helpful video. you did a great job! Keep em coming!

[mattiyeh]

@jinwig i think he meant that if digoxin is given to a normokalemic patient, then they run the risk of developing HYPERkalemia as a result of the K+ buildup extracellularly.

However, you are also correct in saying that hypokalemia is a contraindication to digoxin because of the risk of supratherapeutic levels but I don't think he commented on that.

[aelorde]

oh haha intravascular vs.intracellular...gosh I hope I catch it on my test.

[aelorde]

I think he was saying that it would cause hyperkalemia, idk.

i was surprised too, because i know that low potassium causes dig toxicity (i guess Digoxin competes with potassium for the Na/K pump)???

[darwinoo71]

Parasympathetic effect not Parasympatomymetic. . .

[darwinoo71]

Parasympathetic effect not Parasympatomymetic. . .

[darwinoo71]

are u saying Parasympathetic or Parasympatomymetic? i guess u have to clear this words for layperson . Its Parasympathetic effect .

[darwinoo71]

are u saying Parasympathetic or Parasympatomymetic? i guess u have to clear this words for layperson . Its Parasympathetic effect .

[darwinoo71]

are u saying Parasympathetic or Parasympatomymetic? i guess u have to clear this words for layperson . Its Parasympathetic effect .

[u4015003]

Thank you so much.

[madellago]

hi i've got an exam tomorrow.. I'm confused how Digoxin can cause heart block?? Could anyone explain in a simpler way? - Thanks!

[Allibaby78]

Digoxin is contraindicated in hypertrophic cardiomyopathy (HCM) and Wolf-Parkinson-White Syndrome

[ms300sd]

Thank you for your lectures, sir. I wish that we had you lecturing us in nursing school, our instructors are unable to explain things as well as you.

[yiyihappy]

ONLY IF nclex and our school's pharm exam questions are that easy!

[gotfreckles]

Wish you could finish what you were saying at the end. Thats the question, I keep asking....Why not start off with Digi?

[bigstusoccer]

Got a presentation on Digoxin tomorrow! Thanks for providing me with a better understanding! Loved the lecture! :)

[yonigga223]

I got it right!

[ScolarshipBoy1984]

i like ur lectures i found u !!!!!

[AbuHammam2010]

Other indications apart from recurrent bradycardia, for administration of Digoxin specific Fab Fragment are:

• haemodynamic instability

• life-threatening arrhythmias

• serum potassium >5 mmol/l in acute toxicity

• plasma digoxin level >13nmol/l

• ingestion of more than 10 mg digoxin in adults and 4 mg in children

[humanfool123456]

thanku so much , so it causes hyperkaelemia thanks

[humanfool123456]

thanku so much Sir ..... God bless U

[Nkurt]

thanks bro this is imp for every student not only for usmle student ...i am mbbs stu studing in china n we get very few lectures from our teachers because of their poor engish language ...so ur video is very usefu for stu like me

[agungeddy2008]

thks 4 a ur info sir

[ykumait]

sorry , i have a correction here , digoxin toxicity patients have HYPOcalemia ,thank u

[shanmugaprasanna]

@ykumait t causes intracellular potassium level to decrease and hence blood level rises. so hyperkalemia is correct.

[kingCRAM11]

thank u very much sir

[elijahdomingo]

Godbless you. thanks for sharing

[Islamian007]

you said hyper i dont think so please make it clear for me ?

[Islamian007]

how digoxin toxicity cause hypokalemia? i dont know where i m hanging hehe

[o2demand]

helpful clinical videos for USMLE prep

website: o2demand

[sonofagun07]

thank u :)

[phildas]

excellent vid! Many thanks. God Bless for sharing your knowledge.!